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Annual Conference 2016

21 - 24 March 2016
#Microbio16

The Microbiology Society Annual Conference 2016 will be held from 21–24 March at the Arena and Convention Centre (ACC), Liverpool, UK.

The Society's Annual Conference attracts over 1,200 UK and international delegates, and is one of Europe’s largest annual gatherings of microbiologists. Whether you are a veteran microbiologist or just starting out in your career, attending the Microbiology Society’s Annual Conference is a must for all of those with an interest in microbiology.

If you have any questions please email conferences@microbiologysociety.org

Follow us on Twitter @MicrobioSoc

Updates on the Annual Conference 2016 can be found using the hashtag: #Microbio16

Highlights

Microbiology Society Prize Medal Lecture: Decrypting microbe–host signals in the intestinal crypt: from homeostasis to pathology

Microbiology Society Prize Medal Lecture: Decrypting microbe–host signals in the intestinal crypt: from homeostasis to pathology

Fleming Prize Lecture: The unexpected complexity of bacterial genomes

Fleming Prize Lecture: The unexpected complexity of bacterial genomes

Marjory Stephenson Prize Lecture: Petri plates to Petri nets: the path to systems microbiology

Marjory Stephenson Prize Lecture: Petri plates to Petri nets: the path to systems microbiology

Colworth Prize Lecture: Exploiting new biological targets from a whole-cell phenotypic screening campaign for TB drug discovery

Colworth Prize Lecture: Exploiting new biological targets from a whole-cell phenotypic screening campaign for TB drug discovery

Peter Wildy Prize Lecture: Influenza – a world of discoveries, outbreaks and controversy

Peter Wildy Prize Lecture: Influenza – a world of discoveries, outbreaks and controversy

Live at Lunch: International Committee on Taxonomy of Viruses

Live at Lunch: International Committee on Taxonomy of Viruses

Live at Lunch: Big Data or Bust

Live at Lunch: Big Data or Bust

Live at Lunch: An Audience with... Professor Philippe Sansonetti

Live at Lunch: An Audience with... Professor Philippe Sansonetti
Programme

Type

Session

Sunday 20 March, Afternoon

Pre-Conference networking workshop

18:00 - 20:00

Pre-Conference networking workshop

Monday 21 March, Morning

Open address & Hot Topic Lecture: Zika virus, from obscurity to threat

09:15 - 09:50

Open address & Hot Topic Lecture: Zika virus, from obscurity to threat

Crowdsourcing new antibiotics: Novel approaches

Crowdsourcing new antibiotics: the Microbiology Society has been running a project involving students looking for new antibiotics in the soil in seven schools and six undergraduate courses throughout the UK and Ireland. Students from each institution will present their findings, having won a place at the session through a competitive process. Alongside the students, staff will also be presenting posters looking at the pedagogy of the project, and looking at the implementation and educational benefits of self-guided research.

ORGANISERS

Dariel Burdass, Isabel Spence and Theresa Hudson

Chair : Adam Roberts

The Society and society: citizen science and antimicrobial resistance

10:00 - 10:30

The Society and society: citizen science and antimicrobial resistance

UK public investments addressing the AMR challenge

10:30 - 11:00

UK public investments addressing the AMR challenge

The economics causes of and solutions to AMR

11:00 - 11:30

The economics causes of and solutions to AMR

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

The Small World Initiative: current and future vision

12:00 - 12:30

The Small World Initiative: current and future vision

International perspective on the Small World Initiative

12:30 - 13:00

International perspective on the Small World Initiative

Membrane transporters

The movement of small molecules across biological membranes is fundamental to all life. The recent acceleration of knowledge of the structure and function of these proteins has given us unprecedented insight into their mechanism. In parallel, increased understanding of their function and diversity have led to many transporters being added or manipulated in biotechnological processes where uptake or efflux of small molecules from cells is important. This session will offer participants a grand vision of the range of transporters present in microbial systems and their current exploitation in industrial biotechnology and bioenergy (IBBE). The session includes presentations on basic and translational science on a wide range of important uptake systems in bacterial and eukaryotic microbial systems. Topics have been selected based on transport families including members that are already being manipulated in IBBE and others where there is clear untapped potential. The final session will be led by industry to promote knowledge transfer and mix problems and solutions to drive new interactions between scientists at all career stages and industrial stakeholders.

ORGANISERS

Gavin Thomas, Mark Webber, Jeffrey Green and Peter Henderson

Chair : Gavin Thomas

An evolutionary overview of transporters

10:00 - 10:30

An evolutionary overview of transporters

Primary active transporters

10:30 - 11:00

Primary active transporters

Secondary active transporters

11:00 - 11:30

Secondary active transporters

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Chair : Peter Henderson

Structure and mechanism of bacterial ABC transporters

12:00 - 12:30

Structure and mechanism of bacterial ABC transporters

Bacterial ECF transporters

12:30 - 13:00

Bacterial ECF transporters

Nutrition immunity: Metals at the host-pathogen interface

The ability of pathogenic micro-organisms to assimilate sufficient nutrients from their host is fundamental to pathogenicity. Certain inorganic trace elements, including iron, zinc and copper, are essential for life but can also be toxic. The mammalian immune system has harnessed both the essentiality and toxicity of these micronutrients to combat microbial infections: processes collectively known as “nutritional immunity”.

Microbial pathogens require micronutrients not only for cellular development and proliferation, but for counteracting the oxidative killing machinery of the innate immune system: both catalases and superoxide dismutases require metal cofactors for function. In contrast, certain immune phagocytes flood their phagosomes with potentially lethal levels of copper. Therefore, in order to survive and proliferate within a mammalian host, microbial pathogens must deploy highly effective micronutrient sensing, uptake, homeostatic and detoxification systems.

Recently, we have gained a much deeper understanding of the host mechanisms governing nutritional immunity and the sophisticated countermeasures employed by pathogens to circumvent nutritional restriction. Centering on the elemental struggle for nutrients between pathogens and their hosts, this session will cover molecular aspects of nutritional immunity, and will explore the micronutrient uptake strategies of bacterial, fungal, and parasitic human pathogens.

ORGANISERS

Donna MacCallum and Duncan Wilson

Chair : Donna MacCallum

Zinc acquisition by human fungal pathogens

10:00 - 10:30

Zinc acquisition by human fungal pathogens

Cambialistic superoxide dismutases allow S. aureus to circumvent nutritional immunity

10:30 - 11:00

Cambialistic superoxide dismutases allow S. aureus to circumvent nutritional immunity

Offered paper - Human pathogenic fungi: adaptation to zinc nutritional immunity

11:00 - 11:15

Offered paper - Human pathogenic fungi: adaptation to zinc nutritional immunity

Offered paper - Exploiting nutritional immunity for antimicrobial drug discovery

11:15 - 11:30

Offered paper - Exploiting nutritional immunity for antimicrobial drug discovery

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Chair : Duncan Wilson

Nutritional immunity: Metals at the host–pathogen interface

12:00 - 12:30

Nutritional immunity: Metals at the host–pathogen interface

Guts, germs and steel: Microbes and metal in the inflamed gut

12:30 - 13:00

Guts, germs and steel: Microbes and metal in the inflamed gut

Post-translational modifications of proteins

Post-translational modifications used to be the preserve of ‘higher organisms’. However, a plethora of post-translational modifications (PTMs) – both reversible and irreversible – have now been identified in microbes. In particular, recent advances in proteomic technologies have accelerated the rate at which new PTMs are being discovered and characterised. These efforts have revealed a number of important ‘new kids on the block’ that are revolutionising the way we think about microbial physiology. At the same time, we continue to unearth hitherto unexpected insights into the role(s) played by ‘well-established’ PTMs such as glycosylation. In this two-day symposium, the world’s most influential researchers in microbial PTMs will review their fields and provide us with an update about recent advances in chemical modifications as diverse as phosphorylation, fatty acylation and acetylation, PUP/SUMOylation, ubiquitinylation and glycosylation (to name just a few), as well as more unusual modifications that have only recently been discovered. This will be followed by a focused half-day session dedicated exclusively to the technologies that can be used to identify, quantify and investigate PTMs in microbial systems.

ORGANISERS

Martin Welch, Steve Michell, Janet Quinn and Mick Tuite

Chair : Martin Welch

Acetyl phosphate-mediated protein acetylation

10:00 - 10:30

Acetyl phosphate-mediated protein acetylation

Acetylation-dependent signalling in bacterial chemotaxis

10:30 - 11:00

Acetylation-dependent signalling in bacterial chemotaxis

The role of post-translational modification in the PII signal transduction proteins

11:00 - 11:30

The role of post-translational modification in the PII signal transduction proteins

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Chair : Alan Wolfe

Interplay between proteolysis and phosphorylation

12:00 - 12:30

Interplay between proteolysis and phosphorylation

Activation of pore-forming toxins

12:30 - 13:00

Activation of pore-forming toxins

Viral haemorrhagic fevers

Chair : Stephen Griffin

Welcome (SG, MIG) and dedication of the symposium to the memory of Richard Elliott

10:00 - 10:15

Welcome (SG, MIG) and dedication of the symposium to the memory of Richard Elliott

Ebola: response, sequencing, vaccines and survivors

10:15 - 10:45

Ebola: response, sequencing, vaccines and survivors

Loud and quiet – how human macrophages respond to Ebolavirus infection

10:45 - 11:15

Loud and quiet – how human macrophages respond to Ebolavirus infection

Refreshments and exhibition

11:15 - 11:45

Refreshments and exhibition

Hantaviruses and their targets, and their targets' targets, and their targets' targets' targets

11:45 - 12:15

Hantaviruses and their targets, and their targets' targets, and their targets' targets' targets

Offered paper - Modelling the evolutionary trajectories of an expanding Morbillivirus genus

12:15 - 12:30

Offered paper - Modelling the evolutionary trajectories of an expanding Morbillivirus genus

Offered paper - Intra-patient Ebola virus genome variation correlates with outcome of infection

12:30 - 12:45

Offered paper - Intra-patient Ebola virus genome variation correlates with outcome of infection

Offered paper - Mutational analysis of conserved motifs of the Rift Valley fever virus nucleoprotein indicates novel functional residues

12:45 - 13:00

Offered paper - Mutational analysis of conserved motifs of the Rift Valley fever virus nucleoprotein indicates novel functional residues

Monday 21 March, Afternoon

Crowdsourcing new antibiotics: Novel Approaches Poster Exhibition

13:00 - 14:30

Crowdsourcing new antibiotics: Novel Approaches Poster Exhibition

Lunch, exhibition & poster viewing

13:00 - 14:30

Lunch, exhibition & poster viewing

Nutrition immunity: Metals at the host-pathogen interface

The ability of pathogenic micro-organisms to assimilate sufficient nutrients from their host is fundamental to pathogenicity. Certain inorganic trace elements, including iron, zinc and copper, are essential for life but can also be toxic. The mammalian immune system has harnessed both the essentiality and toxicity of these micronutrients to combat microbial infections: processes collectively known as “nutritional immunity”.

Microbial pathogens require micronutrients not only for cellular development and proliferation, but for counteracting the oxidative killing machinery of the innate immune system: both catalases and superoxide dismutases require metal cofactors for function. In contrast, certain immune phagocytes flood their phagosomes with potentially lethal levels of copper. Therefore, in order to survive and proliferate within a mammalian host, microbial pathogens must deploy highly effective micronutrient sensing, uptake, homeostatic and detoxification systems.

Recently, we have gained a much deeper understanding of the host mechanisms governing nutritional immunity and the sophisticated countermeasures employed by pathogens to circumvent nutritional restriction. Centering on the elemental struggle for nutrients between pathogens and their hosts, this session will cover molecular aspects of nutritional immunity, and will explore the micronutrient uptake strategies of bacterial, fungal, and parasitic human pathogens.

ORGANISERS

Donna MacCallum and Duncan Wilson

Battling against nutritional immunity: Bacterial systems for avoiding zinc and copper stress

13:00 - 13:30

Battling against nutritional immunity: Bacterial systems for avoiding zinc and copper stress

Live at Lunch: Early Career Microbiologists' Forum launch event

13:30 - 14:15

Live at Lunch: Early Career Microbiologists' Forum launch event

Crowdsourcing new antibiotics: Novel approaches

Crowdsourcing new antibiotics: the Microbiology Society has been running a project involving students looking for new antibiotics in the soil in seven schools and six undergraduate courses throughout the UK and Ireland. Students from each institution will present their findings, having won a place at the session through a competitive process. Alongside the students, staff will also be presenting posters looking at the pedagogy of the project, and looking at the implementation and educational benefits of self-guided research.

ORGANISERS

Dariel Burdass, Isabel Spence and Theresa Hudson

Why is soil such a good hunting ground for antibiotics?

14:30 - 15:00

Why is soil such a good hunting ground for antibiotics?

Isolation and growth of uncultured microbes using iChips

15:00 - 15:30

Isolation and growth of uncultured microbes using iChips

Refreshments and exhibition

15:30 - 16:00

Refreshments and exhibition

Experiences implementing the Small World Initiative: an undergraduate perspective

16:00 - 16:30

Experiences implementing the Small World Initiative: an undergraduate perspective

Experiences of implementing the Small World Initiative: A school partnership perspective

16:30 - 17:00

Experiences of implementing the Small World Initiative: A school partnership perspective

Using Citizen Science in the search for new antibiotics

17:00 - 17:30

Using Citizen Science in the search for new antibiotics

Networking

17:30 - 18:00

Networking

Membrane transporters

The movement of small molecules across biological membranes is fundamental to all life. The recent acceleration of knowledge of the structure and function of these proteins has given us unprecedented insight into their mechanism. In parallel, increased understanding of their function and diversity have led to many transporters being added or manipulated in biotechnological processes where uptake or efflux of small molecules from cells is important. This session will offer participants a grand vision of the range of transporters present in microbial systems and their current exploitation in industrial biotechnology and bioenergy (IBBE). The session includes presentations on basic and translational science on a wide range of important uptake systems in bacterial and eukaryotic microbial systems. Topics have been selected based on transport families including members that are already being manipulated in IBBE and others where there is clear untapped potential. The final session will be led by industry to promote knowledge transfer and mix problems and solutions to drive new interactions between scientists at all career stages and industrial stakeholders.

ORGANISERS

Gavin Thomas, Mark Webber, Jeffrey Green and Peter Henderson

Chair : Roslyn Bill

Bacterial TRAP transporters

14:30 - 15:00

Bacterial TRAP transporters

Function and diversity in bacterial sugar transporters

15:00 - 15:30

Function and diversity in bacterial sugar transporters

Refreshments and exhibition

15:30 - 16:15

Refreshments and exhibition

Chair : Roslyn Bill

Offered paper - Structural and functional analyses of the outer membrane transport of aromatic hydrocarbons by the biodegrader Pseudomonas putida F1

16:15 - 16:30

Offered paper - Structural and functional analyses of the outer membrane transport of aromatic hydrocarbons by the biodegrader Pseudomonas putida F1

Offered paper - ABC-transporters and histidine kinases communicate to regulate antimicrobial peptide resistance in Gram-positive bacteria

16:30 - 16:45

Offered paper - ABC-transporters and histidine kinases communicate to regulate antimicrobial peptide resistance in Gram-positive bacteria

Offered paper - Structural basis for nutrient acquisition by dominant members of the human gut microbiota

16:45 - 17:00

Offered paper - Structural basis for nutrient acquisition by dominant members of the human gut microbiota

Structural basis of proton coupled transport in the PTR/POT family of membrane proteins

17:00 - 17:30

Structural basis of proton coupled transport in the PTR/POT family of membrane proteins

Efflux of metabolites in bacteria and its exploitation in biotechnology

17:30 - 18:00

Efflux of metabolites in bacteria and its exploitation in biotechnology

Microbial evasion of host defences

Many pathogens owe their success to elaborate virulence strategies that enable them to evade host immune defences. Taking the military analogy, they take approaches such as (i) ‘Don’t be seen’ by escaping into cells and initiating autophagy, (ii) ‘Don’t be targeted’ by coating their surface to generate a camouflage that cannot be detected and inactivating complement, (iii) ‘Don’t be killed’ by varying surface activators, and (iv) ‘Fight when necessary’ by deploying weapons such as toxins. This symposium will cover all these aspects with specific examples highlighting recent advances and describing the multifactoral evasion of the immune system elicited by certain pathogens.

ORGANISERS

Mark Stevens, Kim Hardie, Petra Oyston, Sabine Totemeyer and Ross Fitzgerald

Chair : Jo Stevens

Non-proteinaceous virulence factors of Francisella tularensis

14:30 - 15:00

Non-proteinaceous virulence factors of Francisella tularensis

Peptidoglycan synthesis in Chlamydia: Balancing immune evasion with requirements for cell division

15:00 - 15:30

Peptidoglycan synthesis in Chlamydia: Balancing immune evasion with requirements for cell division

Autophagy and intracellular bacteria

15:30 - 16:00

Autophagy and intracellular bacteria

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Using genome-wide studies to understand susceptibility to tuberculosis

16:30 - 17:00

Using genome-wide studies to understand susceptibility to tuberculosis

Molecular mechanisms of immune evasion: From complement to toxins

17:00 - 17:30

Molecular mechanisms of immune evasion: From complement to toxins

Host–parasite interactions under systemic conditions

17:30 - 18:00

Host–parasite interactions under systemic conditions

Post-translational modifications of proteins

Post-translational modifications used to be the preserve of ‘higher organisms’. However, a plethora of post-translational modifications (PTMs) – both reversible and irreversible – have now been identified in microbes. In particular, recent advances in proteomic technologies have accelerated the rate at which new PTMs are being discovered and characterised. These efforts have revealed a number of important ‘new kids on the block’ that are revolutionising the way we think about microbial physiology. At the same time, we continue to unearth hitherto unexpected insights into the role(s) played by ‘well-established’ PTMs such as glycosylation. In this two-day symposium, the world’s most influential researchers in microbial PTMs will review their fields and provide us with an update about recent advances in chemical modifications as diverse as phosphorylation, fatty acylation and acetylation, PUP/SUMOylation, ubiquitinylation and glycosylation (to name just a few), as well as more unusual modifications that have only recently been discovered. This will be followed by a focused half-day session dedicated exclusively to the technologies that can be used to identify, quantify and investigate PTMs in microbial systems.

ORGANISERS

Martin Welch, Steve Michell, Janet Quinn and Mick Tuite

Chair : Steve Michell

Phosphorylation networks: Extensive communication between the sensor kinases controlling virulence in Pseudomonas aeruginosa

14:30 - 15:00

Phosphorylation networks: Extensive communication between the sensor kinases controlling virulence in Pseudomonas aeruginosa

Offered paper - ADP-ribosylating sirtuins in the microbial redox defence

15:00 - 15:15

Offered paper - ADP-ribosylating sirtuins in the microbial redox defence

Post-translational regulation of Type VI secretion in Serratia marcescens

15:15 - 15:45

Post-translational regulation of Type VI secretion in Serratia marcescens

Offered paper - Functional analysis of the Legionella pneumophila effector LtpM reveals a novel cytotoxic glycosyltransferase domain

15:45 - 16:00

Offered paper - Functional analysis of the Legionella pneumophila effector LtpM reveals a novel cytotoxic glycosyltransferase domain

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Chair : Stephen Porter

Pupylation-dependent and -independent proteasomal degradation in mycobacteria

16:30 - 17:00

Pupylation-dependent and -independent proteasomal degradation in mycobacteria

Offered paper - Biochemical characterisation of the Aedes aegypti SUMOylation pathway

17:00 - 17:15

Offered paper - Biochemical characterisation of the Aedes aegypti SUMOylation pathway

Functions of polyubiquitin chains in DNA damage bypass in budding yeast

17:15 - 17:45

Functions of polyubiquitin chains in DNA damage bypass in budding yeast

The impact of climate change on disease transmission

Climate change has the potential to influence animal and human disease in several different ways. An increase in extreme weather events will likely disrupt existing food and water supplies, with risk of direct contamination of food supplies, increased susceptibility of crops to disease, overloading of water purification plants / disruption of water supplies leading to increased water spoilage, and risk of transmission of water borne diseases such as Cryptospordium, cholera, Giardia, as well as disruption of healthcare facilities and societal organisation resulting in epidemics. Vector-borne diseases of animals, plants and humans will likely result in changes in global distribution. Examples include: Phythophthora infestans (potato and tomato blight); vector-borne protozoal diseases such as malaria (Anopheles spp. mosquito), and vector-borne viral diseases such as Lyme’s disease (Ixodes spp. tick) and dengue (Aedes spp. esp. aegyptia). This session will focus on the effect of climate change on the epidemiology of infectious of diseases of animals and humans and highlight how new strategies will need to be developed to tackle the spread of condition such as malaria, into previously non-affected areas.

ORGANISERS

Kevin Kavanagh and Justin Pachebat

Chair : Kevin Kavanagh

Evolution in action: Climate change, biodiversity dynamics and emerging infectious disease

14:30 - 15:00

Evolution in action: Climate change, biodiversity dynamics and emerging infectious disease

Impact of environmental changes on ticks and tick-borne diseases

15:00 - 15:30

Impact of environmental changes on ticks and tick-borne diseases

Offered paper - Host inflammatory response to mosquito bites defined severity of mosquito-transmitted virus infection

15:30 - 15:45

Offered paper - Host inflammatory response to mosquito bites defined severity of mosquito-transmitted virus infection

Offered paper - Development of a rapid neutralisation assay for Bluetongue virus

15:45 - 16:00

Offered paper - Development of a rapid neutralisation assay for Bluetongue virus

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Chair : Justin Pachebat

Binomics of temperate and tropical culicoides: Knowledge gaps and consequences for transmission of culicoides-borne viruses

16:30 - 17:00

Binomics of temperate and tropical culicoides: Knowledge gaps and consequences for transmission of culicoides-borne viruses

Future impact of climate change on infectious diseases of animals

17:00 - 17:30

Future impact of climate change on infectious diseases of animals

Viral haemorrhagic fevers

Chair : Mirren Iturriza-Gomara

Ebola virus innate immune evasion functions as antiviral targets

14:30 - 15:00

Ebola virus innate immune evasion functions as antiviral targets

Ebola virus entry and release: role of the viral glycoprotein

15:00 - 15:30

Ebola virus entry and release: role of the viral glycoprotein

Broadly-neutralising antibodies to dengue virus

15:30 - 16:00

Broadly-neutralising antibodies to dengue virus

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Chair : Mirren Iturriza-Gomara

Host responses to Lassa fever

16:30 - 17:00

Host responses to Lassa fever

Flavivirus drug discovery

17:00 - 17:30

Flavivirus drug discovery

Viral haemorrhagic fevers other than Ebola virus

17:30 - 18:00

Viral haemorrhagic fevers other than Ebola virus

Peter Wildy Prize Lecture: Influenza – a world of discoveries, outbreaks and controversy

18:10 - 19:00

Peter Wildy Prize Lecture: Influenza – a world of discoveries, outbreaks and controversy

Crowdsourcing new antibiotics: Novel Approaches Poster Exhibition

19:00 - 21:00

Crowdsourcing new antibiotics: Novel Approaches Poster Exhibition

Poster viewing, drinks & exhibition

19:00 - 21:00

Poster viewing, drinks & exhibition

Meet the Speakers

19:30 - 20:30

Meet the Speakers

Society Band Night: The Radicles

20:15 - 22:00

Society Band Night: The Radicles

Tuesday 22 March, Morning

Microbiology Society Prize Medal Lecture: Decrypting microbe–host signals in the intestinal crypt: from homeostasis to pathology

09:00 - 09:50

Microbiology Society Prize Medal Lecture: Decrypting microbe–host signals in the intestinal crypt: from homeostasis to pathology

Membrane transporters

The movement of small molecules across biological membranes is fundamental to all life. The recent acceleration of knowledge of the structure and function of these proteins has given us unprecedented insight into their mechanism. In parallel, increased understanding of their function and diversity have led to many transporters being added or manipulated in biotechnological processes where uptake or efflux of small molecules from cells is important. This session will offer participants a grand vision of the range of transporters present in microbial systems and their current exploitation in industrial biotechnology and bioenergy (IBBE). The session includes presentations on basic and translational science on a wide range of important uptake systems in bacterial and eukaryotic microbial systems. Topics have been selected based on transport families including members that are already being manipulated in IBBE and others where there is clear untapped potential. The final session will be led by industry to promote knowledge transfer and mix problems and solutions to drive new interactions between scientists at all career stages and industrial stakeholders.

ORGANISERS

Gavin Thomas, Mark Webber, Jeffrey Green and Peter Henderson

Chair : Jeffrey Green

Identifying sugar transporters in filamentous fungi for engineering biofuel-producing yeast

10:00 - 10:30

Identifying sugar transporters in filamentous fungi for engineering biofuel-producing yeast

Hijacked then lost in translation: The plight of the recombinant host cell in membrane protein structural biology projects

10:30 - 11:00

Hijacked then lost in translation: The plight of the recombinant host cell in membrane protein structural biology projects

Offered paper - Engineering the bacterial flagellum: conversion into a high efficiency protein secretion machine

11:00 - 11:15

Offered paper - Engineering the bacterial flagellum: conversion into a high efficiency protein secretion machine

Offered paper - Exploring the potential TRAP and ABC solute uptake transporters from the phototroph Rhodopseudomonas palustris for use in biotechnology

11:15 - 11:30

Offered paper - Exploring the potential TRAP and ABC solute uptake transporters from the phototroph Rhodopseudomonas palustris for use in biotechnology

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

An example from industry

12:00 - 13:00

An example from industry

Microbial evasion of host defences

Many pathogens owe their success to elaborate virulence strategies that enable them to evade host immune defences. Taking the military analogy, they take approaches such as (i) ‘Don’t be seen’ by escaping into cells and initiating autophagy, (ii) ‘Don’t be targeted’ by coating their surface to generate a camouflage that cannot be detected and inactivating complement, (iii) ‘Don’t be killed’ by varying surface activators, and (iv) ‘Fight when necessary’ by deploying weapons such as toxins. This symposium will cover all these aspects with specific examples highlighting recent advances and describing the multifactoral evasion of the immune system elicited by certain pathogens.

ORGANISERS

Mark Stevens, Kim Hardie, Petra Oyston, Sabine Totemeyer and Ross Fitzgerald

Now you see me, now you don't: Innate immune recognition of endoplasmic reticulum stress during infection with Brucella abortus

10:00 - 10:30

Now you see me, now you don't: Innate immune recognition of endoplasmic reticulum stress during infection with Brucella abortus

Manipulation of the immune system through engagement of lectin receptors by bacterial pathogens

10:30 - 11:00

Manipulation of the immune system through engagement of lectin receptors by bacterial pathogens

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

"Class"-ified information: Type four pili and meningoccocal immune evasion

11:30 - 12:00

"Class"-ified information: Type four pili and meningoccocal immune evasion

Microbial evasion or immune tolerance? Pneumococcal interactions with host immunity during carriage and disease

12:00 - 12:30

Microbial evasion or immune tolerance? Pneumococcal interactions with host immunity during carriage and disease

Legionella modulators of membrane dynamics and cell migration

12:30 - 13:00

Legionella modulators of membrane dynamics and cell migration

Mining microbial diversity for pleasure and profit

Microbes are wonderful chemists and their ability to produce pleasurable flavours and fragrances in foods and drinks has been exploited for thousands of years. Technological progress is now allowing us to extend the uses of yeasts and bacteria from things like brewing and cheese-making all the way to making renewable chemicals to reduce the rate of climate change. This session will bring together university and industry scientists to showcase the extraordinary variety of Nature’s microbial treasure trove and demonstrate how advances in genome mining and synthetic biology are unlocking this natural diversity to an ever-increasing extent. The benefits to society of re-discovering traditional foods and flavours as well as building new businesses harnessing the power of microbiology are many and an exciting ‘taste’ of future possibilities will permeate the meeting.

ORGANISERS

Ian Roberts, Ed Louis, John Morrissey and Elinor Thompson

Chair : Ian Roberts

Exploiting yeast intra-species diversity to unravel complex phenotypes

10:00 - 10:30

Exploiting yeast intra-species diversity to unravel complex phenotypes

Kluyveromyces marxianus – an emerging yeast for cell factory applications

10:30 - 11:00

Kluyveromyces marxianus – an emerging yeast for cell factory applications

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

Chair : John Morrissey

Offered paper - Mining marine cellular communication networks for translational societal benefit

11:30 - 11:45

Offered paper - Mining marine cellular communication networks for translational societal benefit

Offered paper - The bacteriocin arsenal of Pseudomonas

11:45 - 12:00

Offered paper - The bacteriocin arsenal of Pseudomonas

Zygosaccharomyces bailii: Reorientating a spoilage yeast for biotechnology

12:00 - 12:30

Zygosaccharomyces bailii: Reorientating a spoilage yeast for biotechnology

Production of recombinant proteins and high-value chemicals in Chlamydomonas reinhardtii

12:30 - 13:00

Production of recombinant proteins and high-value chemicals in Chlamydomonas reinhardtii

Mycobacteria

The One Health paradigm posits that human, animal and environmental health are intimately linked. The Mycobacterium tuberculosis complex (MTBC), the assembly of pathogens that cause tuberculosis (TB) in man and a range of wild and domesticated mammals, and the environmentally prevalent non-tuberculous mycobacteria (NTM) represent an ideal group of bacteria in which to explore One Health concepts in infectious disease. We bring together key researchers in the mycobacterial field that encompass the diversity and complexity of infections caused by these bacteria.

ORGANISERS

Steve Michell, Steven Gordon and Sabine Totemeyer

Chair : Stephen Michell and Sabine Totemeyer

Tuberculosis and One Health: comparative analysis of human and bovine tubercle bacilli

10:00 - 10:30

Tuberculosis and One Health: comparative analysis of human and bovine tubercle bacilli

Leprosy – zoonosis and anthroponosis

10:30 - 11:00

Leprosy – zoonosis and anthroponosis

Mycobacterium avium, subspecies paratuberculosis and Johne’s disease

11:00 - 11:30

Mycobacterium avium, subspecies paratuberculosis and Johne’s disease

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Chair : Stephen Michell and Stephen Gordon

Daring to be different – heterogeneity among identical twins

12:00 - 12:30

Daring to be different – heterogeneity among identical twins

Offered paper - The Buruli ulcer exotoxin, mycolactone, inhibits Sec61-dependent translocation of secreted proteins

12:30 - 12:45

Offered paper - The Buruli ulcer exotoxin, mycolactone, inhibits Sec61-dependent translocation of secreted proteins

Offered paper - Interactions between M. avium with avian and human macrophage

12:45 - 13:00

Offered paper - Interactions between M. avium with avian and human macrophage

Post-translational modifications of proteins

Post-translational modifications used to be the preserve of ‘higher organisms’. However, a plethora of post-translational modifications (PTMs) – both reversible and irreversible – have now been identified in microbes. In particular, recent advances in proteomic technologies have accelerated the rate at which new PTMs are being discovered and characterised. These efforts have revealed a number of important ‘new kids on the block’ that are revolutionising the way we think about microbial physiology. At the same time, we continue to unearth hitherto unexpected insights into the role(s) played by ‘well-established’ PTMs such as glycosylation. In this two-day symposium, the world’s most influential researchers in microbial PTMs will review their fields and provide us with an update about recent advances in chemical modifications as diverse as phosphorylation, fatty acylation and acetylation, PUP/SUMOylation, ubiquitinylation and glycosylation (to name just a few), as well as more unusual modifications that have only recently been discovered. This will be followed by a focused half-day session dedicated exclusively to the technologies that can be used to identify, quantify and investigate PTMs in microbial systems.

ORGANISERS

Martin Welch, Steve Michell, Janet Quinn and Mick Tuite

Chair : Sarah Coulthurst

Protein O-glycosylation in Actinobacteria: What's it for?

10:00 - 10:30

Protein O-glycosylation in Actinobacteria: What's it for?

Characterising protein glycosylation in microbial pathogens

10:30 - 11:00

Characterising protein glycosylation in microbial pathogens

Know your enemy: Fungal cell wall glycans that drive immune recognition mechanisms

11:00 - 11:30

Know your enemy: Fungal cell wall glycans that drive immune recognition mechanisms

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Chair : Karin Sauer

Phosphoarginine serves as a degradation tag of the ClpC:ClpP protease

12:00 - 12:30

Phosphoarginine serves as a degradation tag of the ClpC:ClpP protease

A second line of defence: Exploring the functionality and hidden roles of gliotoxin bisthiomethylation in Aspergillus fumigateus

12:30 - 13:00

A second line of defence: Exploring the functionality and hidden roles of gliotoxin bisthiomethylation in Aspergillus fumigateus

The "Red Queen" and the genome: Conflict in shaping microbial evolution

The evolution of life is affected profoundly by interactions between organisms changing over time. Conflict plays a large part in this: from competition for food and mates between members of the same species, to predator versus prey and host versus parasite relationships. These "Red Queen" effects, whereby organisms evolve quickly and competitively in order to remain in the same niche, have been used to explain species' constant extinction rates, and the prevalence of sex. Recent advances in genomics have provided evidence for 'molecular arms races' between species, and a variety of experimental approaches have shed further light on the genetics of conflict in viruses, bacteria, and microbial eukaryotes. This session aims to host a discussion of recent developments relevant to evolutionary microbiology and parasitology.

ORGANISERS

Gareth Bloomfield

Chair : Gareth Bloomfield

Protection from the "Red Queen": Co-evolution and conflict among hosts, parasites, and defensive microbes

10:00 - 10:30

Protection from the "Red Queen": Co-evolution and conflict among hosts, parasites, and defensive microbes

Co-evolution of mycobacteria with their hosts

10:30 - 11:00

Co-evolution of mycobacteria with their hosts

Offered paper - Genotypic and phenotypic diversity arising during the clonal expansion of the current MDR monophasic Salmonella typhimurium epidemic in the UK

11:00 - 11:15

Offered paper - Genotypic and phenotypic diversity arising during the clonal expansion of the current MDR monophasic Salmonella typhimurium epidemic in the UK

Offered paper - Public goods cooperation in P. aeruginosa

11:15 - 11:30

Offered paper - Public goods cooperation in P. aeruginosa

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Chair : Catarina Gadelha

Polychromatic 'greenbeard' genes protect against defection strategies in a social amoeba

12:00 - 12:30

Polychromatic 'greenbeard' genes protect against defection strategies in a social amoeba

Genome evolution in the Chlamydiae – ubiquitous intracellular symbionts and pathogens

12:30 - 13:00

Genome evolution in the Chlamydiae – ubiquitous intracellular symbionts and pathogens

The hostile cell: Intrinsic antiviral immunity – part 1

The innate immune system represents the first line of defence against infection. It consists of a number of constitutively expressed and inducible factors that suppress or prevent virus infection. Some of these are well-characterised, others are still poorly understood. This symposium will highlight the roles of these anti-viral factors in the immune responses of both vertebrate and non-vertebrate species, and discuss the mechanisms by which they create an environment hostile to virus replication. Virus countermeasures to these processes will also be described. The symposium will take place concurrently with the restriction factor workshop, allowing a forum for the exchange of ideas between disparate groups of virologists.

ORGANISERS

Andrew MacDonald, James Stewart

Chair : James Stewart and David Evans

The role of PYHIN proteins in innate immunity

10:00 - 10:30

The role of PYHIN proteins in innate immunity

Using genetic approaches to identify factors involved in cell-intrinsic immunity

10:30 - 11:00

Using genetic approaches to identify factors involved in cell-intrinsic immunity

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

Antiviral function of Mx proteins

11:30 - 12:00

Antiviral function of Mx proteins

Offered paper - Bacterial flagellin opens the door for virus entry

12:00 - 12:15

Offered paper - Bacterial flagellin opens the door for virus entry

Offered paper - Species difference in ANP32A underlies influenza A virus polymerase host restriction

12:15 - 12:30

Offered paper - Species difference in ANP32A underlies influenza A virus polymerase host restriction

Induction and suppression of the interferon response by RNA viruses

12:30 - 13:00

Induction and suppression of the interferon response by RNA viruses

Tuesday 22 March, Afternoon

Lunch, exhibition & poster viewing

13:00 - 14:30

Lunch, exhibition & poster viewing

The "Red Queen" and the genome: Conflict in shaping microbial evolution

The evolution of life is affected profoundly by interactions between organisms changing over time. Conflict plays a large part in this: from competition for food and mates between members of the same species, to predator versus prey and host versus parasite relationships. These "Red Queen" effects, whereby organisms evolve quickly and competitively in order to remain in the same niche, have been used to explain species' constant extinction rates, and the prevalence of sex. Recent advances in genomics have provided evidence for 'molecular arms races' between species, and a variety of experimental approaches have shed further light on the genetics of conflict in viruses, bacteria, and microbial eukaryotes. This session aims to host a discussion of recent developments relevant to evolutionary microbiology and parasitology.

ORGANISERS

Gareth Bloomfield

Cyanobacterial resistance to phage infection: Implications for genome evolution and host–phage coexistence

13:00 - 13:30

Cyanobacterial resistance to phage infection: Implications for genome evolution and host–phage coexistence

Chair : Kayla King

Carefree Coccidia? Evolution of a hit and run parasite…

14:30 - 15:00

Carefree Coccidia? Evolution of a hit and run parasite…

The molecular architecture of a parasite cell surface

15:00 - 15:30

The molecular architecture of a parasite cell surface

AID and gene conversions on both sides of the host–parasite arms race

15:30 - 16:00

AID and gene conversions on both sides of the host–parasite arms race

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Malaria genomics: a constantly evolving population of parasites

16:30 - 17:00

Malaria genomics: a constantly evolving population of parasites

Discovery of novel CRISPR-Cas systems by mining genomic and metagenomic databases

17:00 - 17:30

Discovery of novel CRISPR-Cas systems by mining genomic and metagenomic databases

Offered paper - The structure of phage–bacteria networks from a long-term co-evolution study of arms race and fluctuating selection dynamics

17:30 - 17:45

Offered paper - The structure of phage–bacteria networks from a long-term co-evolution study of arms race and fluctuating selection dynamics

Live at Lunch: Big Data or Bust

13:15 - 14:15

Live at Lunch: Big Data or Bust

Live at Lunch: An Audience with... Professor Philippe Sansonetti

13:30 - 14:15

Live at Lunch: An Audience with... Professor Philippe Sansonetti

Clinical Virology Network

This workshop will involve a range of clinical virology cases or short papers which relate to studies relevant to clinical virology network. Different aspects of clinical virology that will be covered include: differential diagnosis of encephalitis, management of hepatitis, diversity of rotavirus sequences, and diagnosis of respiratory infections.

ORGANISERS

Miren Iturriza-Gomara and Matthew Donati

Chair : William Irving

Update on avian influenza and MERS-CoV

14:00 - 14:30

Update on avian influenza and MERS-CoV

The application of rapid molecular respiratory point of care tests in relation to clinical and infection control paediatric practice

14:30 - 15:00

The application of rapid molecular respiratory point of care tests in relation to clinical and infection control paediatric practice

Commercial company presentations

15:00 - 15:30

Commercial company presentations

Refreshments and exhibition

15:30 - 15:45

Refreshments and exhibition

Chair : Mark Zuckerman

Monitoring and treating hepatitis B carriers now and in the future

15:45 - 16:15

Monitoring and treating hepatitis B carriers now and in the future

Chair's report, Treasurer's report, research report, training and website update

16:15 - 17:00

Chair's report, Treasurer's report, research report, training and website update

Microbial evasion of host defences

Many pathogens owe their success to elaborate virulence strategies that enable them to evade host immune defences. Taking the military analogy, they take approaches such as (i) ‘Don’t be seen’ by escaping into cells and initiating autophagy, (ii) ‘Don’t be targeted’ by coating their surface to generate a camouflage that cannot be detected and inactivating complement, (iii) ‘Don’t be killed’ by varying surface activators, and (iv) ‘Fight when necessary’ by deploying weapons such as toxins. This symposium will cover all these aspects with specific examples highlighting recent advances and describing the multifactoral evasion of the immune system elicited by certain pathogens.

ORGANISERS

Mark Stevens, Kim Hardie, Petra Oyston, Sabine Totemeyer and Ross Fitzgerald

Understanding Campylobacter jejuni-mediated diseases pathogenesis: an update and future challenges

14:30 - 15:00

Understanding Campylobacter jejuni-mediated diseases pathogenesis: an update and future challenges

Role of cell death signalling pathways in antibacterial immune defense

15:00 - 15:30

Role of cell death signalling pathways in antibacterial immune defense

Using Citrobacter rodentium to model enteric bacterial infections and host responses

15:30 - 16:00

Using Citrobacter rodentium to model enteric bacterial infections and host responses

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Intracellular survival strategy of Burkholderia cepacia complex isolates

16:30 - 17:00

Intracellular survival strategy of Burkholderia cepacia complex isolates

Offered paper - Targeting of the host sphingosine-1-phosphate (S1P) axis by intracellular bacterial pathogens: Characterization of bacterial-encoded S1P lyases required for virulence and intracellular survival

17:00 - 17:15

Offered paper - Targeting of the host sphingosine-1-phosphate (S1P) axis by intracellular bacterial pathogens: Characterization of bacterial-encoded S1P lyases required for virulence and intracellular survival

Offered paper - Staphylococcal enterotoxin-like toxin X (SEIX) binds to neutrophils in a sialic acid dependent manner and inhibits neutrophil function

17:15 - 17:30

Offered paper - Staphylococcal enterotoxin-like toxin X (SEIX) binds to neutrophils in a sialic acid dependent manner and inhibits neutrophil function

Yersinia toxin injection

17:30 - 18:00

Yersinia toxin injection

Mining microbial diversity for pleasure and profit

Microbes are wonderful chemists and their ability to produce pleasurable flavours and fragrances in foods and drinks has been exploited for thousands of years. Technological progress is now allowing us to extend the uses of yeasts and bacteria from things like brewing and cheese-making all the way to making renewable chemicals to reduce the rate of climate change. This session will bring together university and industry scientists to showcase the extraordinary variety of Nature’s microbial treasure trove and demonstrate how advances in genome mining and synthetic biology are unlocking this natural diversity to an ever-increasing extent. The benefits to society of re-discovering traditional foods and flavours as well as building new businesses harnessing the power of microbiology are many and an exciting ‘taste’ of future possibilities will permeate the meeting.

ORGANISERS

Ian Roberts, Ed Louis, John Morrissey and Elinor Thompson

Chair : Elinor Thompson

Brewing up biodiversity for biotechnology – flavour variation in British ale yeasts

14:30 - 15:00

Brewing up biodiversity for biotechnology – flavour variation in British ale yeasts

Ecological role of yeast flavours

15:00 - 15:30

Ecological role of yeast flavours

Offered paper - Genetic dissection of lactose assimilation in Kluyveromyces marxianus

15:30 - 15:45

Offered paper - Genetic dissection of lactose assimilation in Kluyveromyces marxianus

Offered paper - New yeast hybrids: Generation and analysis

15:45 - 16:00

Offered paper - New yeast hybrids: Generation and analysis

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Beneficial aspects of S. uvarum, S. kudriavzevii and Saccharomyces hybrids in the aroma synthesis during alcoholic fermentation

16:30 - 17:00

Beneficial aspects of S. uvarum, S. kudriavzevii and Saccharomyces hybrids in the aroma synthesis during alcoholic fermentation

Lactic acid bacteria in cheese for heart health

17:00 - 17:30

Lactic acid bacteria in cheese for heart health

Harnessing raw milk microbes to make cheeses of place: A new frontier for farmhouse cheese

17:30 - 18:00

Harnessing raw milk microbes to make cheeses of place: A new frontier for farmhouse cheese

Mycobacteria

The One Health paradigm posits that human, animal and environmental health are intimately linked. The Mycobacterium tuberculosis complex (MTBC), the assembly of pathogens that cause tuberculosis (TB) in man and a range of wild and domesticated mammals, and the environmentally prevalent non-tuberculous mycobacteria (NTM) represent an ideal group of bacteria in which to explore One Health concepts in infectious disease. We bring together key researchers in the mycobacterial field that encompass the diversity and complexity of infections caused by these bacteria.

ORGANISERS

Steve Michell, Steven Gordon and Sabine Totemeyer

Chair : Stephen Michell and Sabine Totemeyer

Challenges and progress in human TB vaccine development

14:30 - 15:00

Challenges and progress in human TB vaccine development

Offered paper - Hypoxic signalling modulates neutrophil nitric oxide in a zebrafish–Mycobacteria model

15:00 - 15:15

Offered paper - Hypoxic signalling modulates neutrophil nitric oxide in a zebrafish–Mycobacteria model

Offered paper - Peptidoglycan recycling in Mycobacteria

15:15 - 15:30

Offered paper - Peptidoglycan recycling in Mycobacteria

Lysosomal storage disorders cause susceptibility to tuberculosis by compromising macrophage migration

15:30 - 16:00

Lysosomal storage disorders cause susceptibility to tuberculosis by compromising macrophage migration

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Chair : Stephen Michell and Stephen Gordon

The evolution of MTBC and the novel STB

16:30 - 17:00

The evolution of MTBC and the novel STB

Using whole genome sequencing to uncover the biology of NTM infection

17:00 - 17:30

Using whole genome sequencing to uncover the biology of NTM infection

Pain control by Mycobacterium ulcerans secreted mycolactone

17:30 - 18:00

Pain control by Mycobacterium ulcerans secreted mycolactone

Post-translational modifications of proteins

Post-translational modifications used to be the preserve of ‘higher organisms’. However, a plethora of post-translational modifications (PTMs) – both reversible and irreversible – have now been identified in microbes. In particular, recent advances in proteomic technologies have accelerated the rate at which new PTMs are being discovered and characterised. These efforts have revealed a number of important ‘new kids on the block’ that are revolutionising the way we think about microbial physiology. At the same time, we continue to unearth hitherto unexpected insights into the role(s) played by ‘well-established’ PTMs such as glycosylation. In this two-day symposium, the world’s most influential researchers in microbial PTMs will review their fields and provide us with an update about recent advances in chemical modifications as diverse as phosphorylation, fatty acylation and acetylation, PUP/SUMOylation, ubiquitinylation and glycosylation (to name just a few), as well as more unusual modifications that have only recently been discovered. This will be followed by a focused half-day session dedicated exclusively to the technologies that can be used to identify, quantify and investigate PTMs in microbial systems.

ORGANISERS

Martin Welch, Steve Michell, Janet Quinn and Mick Tuite

Chair : Jan Quinn

Proteostasis – balancing the protein economy in Saccharomyces

14:30 - 15:00

Proteostasis – balancing the protein economy in Saccharomyces

Offered paper - Understanding the role of acetyl-lysine post-translational modifications in Campylobacter jejuni

15:00 - 15:15

Offered paper - Understanding the role of acetyl-lysine post-translational modifications in Campylobacter jejuni

The redoxome: from oxidative thiol modification to N-chlorination

15:15 - 15:45

The redoxome: from oxidative thiol modification to N-chlorination

Refreshments and exhibition

15:45 - 16:30

Refreshments and exhibition

Chair : Mick Tuite

Glyco- and quantitative-proteomics in Trypanosoma brucei

16:30 - 17:00

Glyco- and quantitative-proteomics in Trypanosoma brucei

Offered paper - The Streptomyces coelicolor glycoproteome includes enzymes involved in cell wall biogenesis

17:00 - 17:15

Offered paper - The Streptomyces coelicolor glycoproteome includes enzymes involved in cell wall biogenesis

Quantitative proteomics at a global scale – methods and applications in bacteria

17:15 - 17:45

Quantitative proteomics at a global scale – methods and applications in bacteria

The hostile cell: Intrinsic antiviral immunity – part 1

The innate immune system represents the first line of defence against infection. It consists of a number of constitutively expressed and inducible factors that suppress or prevent virus infection. Some of these are well-characterised, others are still poorly understood. This symposium will highlight the roles of these anti-viral factors in the immune responses of both vertebrate and non-vertebrate species, and discuss the mechanisms by which they create an environment hostile to virus replication. Virus countermeasures to these processes will also be described. The symposium will take place concurrently with the restriction factor workshop, allowing a forum for the exchange of ideas between disparate groups of virologists.

ORGANISERS

Andrew MacDonald, James Stewart

Chair : Gill Elliott and James Stewart

Virology meets proteomics: Understanding cellular defense mechanisms against herpesvirus infections

14:30 - 15:00

Virology meets proteomics: Understanding cellular defense mechanisms against herpesvirus infections

Offered paper - Regulation of HSV-1 infection by the non-homologous end joining machinery

15:00 - 15:15

Offered paper - Regulation of HSV-1 infection by the non-homologous end joining machinery

Offered paper - Atypical macropinocytosis of Measles virus particles in lymphocytes

15:15 - 15:30

Offered paper - Atypical macropinocytosis of Measles virus particles in lymphocytes

Tethering virions – an ancient strategy to prevent viral spread

15:30 - 16:00

Tethering virions – an ancient strategy to prevent viral spread

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Offered paper - Direct cell-to-cell spread favoured by wild-type HCMV confers resistance to intrinsic, innate and adaptive immune defences

16:30 - 16:45

Offered paper - Direct cell-to-cell spread favoured by wild-type HCMV confers resistance to intrinsic, innate and adaptive immune defences

Offered paper - Applying advances in light microscopy to the high-resolution tracking of chikungunya virus (CHIKV) non-structural protein 3 (nsP3) in human cells

16:45 - 17:00

Offered paper - Applying advances in light microscopy to the high-resolution tracking of chikungunya virus (CHIKV) non-structural protein 3 (nsP3) in human cells

Defense and counter-defense in antiviral RNA silencing pathways of insects

17:00 - 17:30

Defense and counter-defense in antiviral RNA silencing pathways of insects

Offered paper - MxA-transgenic mice cannot efficiently control influenza A viruses carrying nucleoproteins with human signature

17:30 - 17:45

Offered paper - MxA-transgenic mice cannot efficiently control influenza A viruses carrying nucleoproteins with human signature

Fleming Prize Lecture: The unexpected complexity of bacterial genomes

18:10 - 19:00

Fleming Prize Lecture: The unexpected complexity of bacterial genomes

Poster viewing, drinks & exhibition

19:00 - 21:00

Poster viewing, drinks & exhibition

Live Debate: Human Face of Ebola and Ebola Trials

19:15 - 20:15

Live Debate: Human Face of Ebola and Ebola Trials

Wednesday 23 March, Morning

Marjory Stephenson Prize Lecture: Petri plates to Petri nets: the path to systems microbiology

09:00 - 09:50

Marjory Stephenson Prize Lecture: Petri plates to Petri nets: the path to systems microbiology

Prokaryotic infection forum

Offered papers will be presented in areas related to infections caused by prokaryotes of human, veterinary or botanical significance including epidemiology, diagnosis, identification, typing, pathogenesis, treatment, antimicrobial agents and resistance, prevention, virulence factors, host responses and immunity, transmission, and models of infection at the cell, tissue or whole organism level.

ORGANISERS

Sheila Patrick and Sabine Totemeyer

Chair : Sheila Patrick and Sabine Totemeyer

Listeria monocytogenes: a unique model in infection biology

10:00 - 10:30

Listeria monocytogenes: a unique model in infection biology

Offered paper - Differential expression of a phase variable type I restriction modification system impacts the virulence of Streptococcus pneumoniae

10:30 - 10:45

Offered paper - Differential expression of a phase variable type I restriction modification system impacts the virulence of Streptococcus pneumoniae

Offered paper - Polymeric artificial cellular environments interfere with the expression of virulence factors in Vibrio chloerae compromising its pathogenesis

10:45 - 11:00

Offered paper - Polymeric artificial cellular environments interfere with the expression of virulence factors in Vibrio chloerae compromising its pathogenesis

Offered paper - Periodontal pathogen sialidases at the oral host–pathogen interface

11:00 - 11:15

Offered paper - Periodontal pathogen sialidases at the oral host–pathogen interface

Offered paper - LPS accelerates uptake of bacterial outer membrane vesicles into host cells

11:15 - 11:30

Offered paper - LPS accelerates uptake of bacterial outer membrane vesicles into host cells

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Chair : Sheila Patrick and Sabine Totemeyer

Offered paper - Use of genomics to analyse the geographical and historical diversity of a Pseudomonas aeruginosa transmissible strain

12:00 - 12:15

Offered paper - Use of genomics to analyse the geographical and historical diversity of a Pseudomonas aeruginosa transmissible strain

Offered paper - A microbiota approach to an interdigital skin infection

12:15 - 12:30

Offered paper - A microbiota approach to an interdigital skin infection

Offered paper - Inhibition of Helicobacter pylori by sulfonamides

12:30 - 12:45

Offered paper - Inhibition of Helicobacter pylori by sulfonamides

Offered paper - The impact of the microbiota on Clostridium difficile colonisation and disease severity

12:45 - 13:00

Offered paper - The impact of the microbiota on Clostridium difficile colonisation and disease severity

The model microbe – how far can it go?

For many years, researchers have turned to simple and experimentally amenable microbial organisms to understand the basic workings of the cell. In recent years the range of organisms used in research has expanded in parallel with the huge developments in genome sequencing and molecular biology. As the genetic basis of many human diseases is becoming clear, molecular studies in simplified model systems can be used to determine gene function and give insights into disease pathology. This timely and widely relevant session will highlight and promote the systems and experimental approaches being used today.

ORGANISERS

Jason King, Elinor Thompson and Gareth Bloomfield

Chair : Gareth Bloomfield

Surviving protein quality control failures: From yeast to mammals

10:00 - 10:30

Surviving protein quality control failures: From yeast to mammals

Deciphering the roles regulatory RNAs play in the lifestyles of Bacillus subtilis

10:30 - 11:00

Deciphering the roles regulatory RNAs play in the lifestyles of Bacillus subtilis

Genome regulation and cellular ageing in fission yeast

11:00 - 11:30

Genome regulation and cellular ageing in fission yeast

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Chair : Ellen Nisbet

Insights into the origin of virulence from model organisms

12:00 - 12:30

Insights into the origin of virulence from model organisms

Infecting amoebae with mycobacteria to study conserved mechanisms of innate immunity

12:30 - 13:00

Infecting amoebae with mycobacteria to study conserved mechanisms of innate immunity

Clinical Virology Network

This workshop will involve a range of clinical virology cases or short papers which relate to studies relevant to clinical virology network. Different aspects of clinical virology that will be covered include: differential diagnosis of encephalitis, management of hepatitis, diversity of rotavirus sequences, and diagnosis of respiratory infections.

ORGANISERS

Miren Iturriza-Gomara and Matthew Donati

Chair : Miren Iturriza-Gomara

Offered paper - The role of pseudotypes in influenza pandemic preparedness: an undergraduate-led serology and social media exercise

10:00 - 10:12

Offered paper - The role of pseudotypes in influenza pandemic preparedness: an undergraduate-led serology and social media exercise

Offered paper - Generation of a genetically stable and antigenically matched H3N2 3C.2a live-attenuated influenza virus vaccine candidate

10:12 - 10:24

Offered paper - Generation of a genetically stable and antigenically matched H3N2 3C.2a live-attenuated influenza virus vaccine candidate

Offered paper - The role of protease in studies making use of viral pseudotype particles

10:24 - 10:36

Offered paper - The role of protease in studies making use of viral pseudotype particles

Offered paper - Parainfluenza virus: Genetic diversity, virulence and antiviral susceptibility

10:36 - 10:48

Offered paper - Parainfluenza virus: Genetic diversity, virulence and antiviral susceptibility

Offered paper - Increased detection of Seoul hantavirus in the United Kingdom

10:48 - 11:00

Offered paper - Increased detection of Seoul hantavirus in the United Kingdom

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

Chair : Matthew Donati

Offered paper - Isolation of patients with influenza: experience of Newcastle upon Tyne Hospitals NHS Foundation Trust 2014/2015

11:30 - 11:42

Offered paper - Isolation of patients with influenza: experience of Newcastle upon Tyne Hospitals NHS Foundation Trust 2014/2015

Offered paper - Genotypic and phenotypic determination of drug resistance in herpes simplex virus type 1 and 2 infections in the UK

11:42 - 11:54

Offered paper - Genotypic and phenotypic determination of drug resistance in herpes simplex virus type 1 and 2 infections in the UK

Offered paper - A prospective study of Epstein-Barr virus and host immune response gene expression in sequential blood samples collected from bone marrow transplant recipients

11:54 - 12:06

Offered paper - A prospective study of Epstein-Barr virus and host immune response gene expression in sequential blood samples collected from bone marrow transplant recipients

Offered paper - Neonatal HSV disease in the UK and RoI: burden of disease and role of risk factors

12:06 - 12:18

Offered paper - Neonatal HSV disease in the UK and RoI: burden of disease and role of risk factors

Offered paper - Establishing a framework for pre-emptive drug resistance genotyping: next generation sequencing following primary HCMV infection after high-risk, seromismatched transplantation

12:18 - 12:30

Offered paper - Establishing a framework for pre-emptive drug resistance genotyping: next generation sequencing following primary HCMV infection after high-risk, seromismatched transplantation

Offered paper - Whole genome sequencing of HIV-1 – a multifunctional tool

12:30 - 12:42

Offered paper - Whole genome sequencing of HIV-1 – a multifunctional tool

Offered paper - Norovirus evolution: understanding and characterising the emergence of novel strains in the population

12:42 - 12:54

Offered paper - Norovirus evolution: understanding and characterising the emergence of novel strains in the population

Environmental and applied microbiology forum

Offered papers focusing on any area in microbial ecology, including (non-human) host–microbe communities and interactions, marine and freshwater microbiology, soil and geomicrobiology, and air-, cryo- and extremophile microbiology will be presented.

ORGANISERS

Geertje Van Keulen, Ryan Seipke and Sarah Kuehne

Chair : Ryan Seipke

Finding a new niche: mining for antibiotics in the nest of leafcutter ants

10:00 - 10:30

Finding a new niche: mining for antibiotics in the nest of leafcutter ants

Chair : Geertje Van Keulen

Offered paper - Microbial life and the death of glaciers: How does microbial ecosystem engineering accelerate glacier melting?

10:30 - 10:45

Offered paper - Microbial life and the death of glaciers: How does microbial ecosystem engineering accelerate glacier melting?

Offered paper - Multiple drug resistance identified from a soil microbiome using functional metagenomics

10:45 - 11:00

Offered paper - Multiple drug resistance identified from a soil microbiome using functional metagenomics

Offered paper - Adaptation to environmental change comes with a cost of reduced bacterial community ecosystem functioning

11:00 - 11:15

Offered paper - Adaptation to environmental change comes with a cost of reduced bacterial community ecosystem functioning

Offered paper - Benthic nitrate reduction is mediated by NAP nitrate reductase along the salinity gradient of an estuarine and coastal bay ecosystem

11:15 - 11:30

Offered paper - Benthic nitrate reduction is mediated by NAP nitrate reductase along the salinity gradient of an estuarine and coastal bay ecosystem

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Chair : Sarah Kuehne

Offered paper - Factors governing in planta growth of Escherichia coli O157:H7

12:00 - 12:15

Offered paper - Factors governing in planta growth of Escherichia coli O157:H7

Offered paper - Isosaccharininc acids from anaerobic, alkaline cellulose degradation products as an organic carbon source within the disposal concept for intermediate level radioactive wastes

12:15 - 12:30

Offered paper - Isosaccharininc acids from anaerobic, alkaline cellulose degradation products as an organic carbon source within the disposal concept for intermediate level radioactive wastes

Offered paper - Syntrophic paraffin biodegradation under methanogenic conditions

12:30 - 12:45

Offered paper - Syntrophic paraffin biodegradation under methanogenic conditions

Offered paper - IMNGS: A comprehensive open resource of processed 16S rRNA microbial profiles for ecology and diversity studies

12:45 - 13:00

Offered paper - IMNGS: A comprehensive open resource of processed 16S rRNA microbial profiles for ecology and diversity studies

Mining microbial diversity for pleasure and profit

Microbes are wonderful chemists and their ability to produce pleasurable flavours and fragrances in foods and drinks has been exploited for thousands of years. Technological progress is now allowing us to extend the uses of yeasts and bacteria from things like brewing and cheese-making all the way to making renewable chemicals to reduce the rate of climate change. This session will bring together university and industry scientists to showcase the extraordinary variety of Nature’s microbial treasure trove and demonstrate how advances in genome mining and synthetic biology are unlocking this natural diversity to an ever-increasing extent. The benefits to society of re-discovering traditional foods and flavours as well as building new businesses harnessing the power of microbiology are many and an exciting ‘taste’ of future possibilities will permeate the meeting.

ORGANISERS

Ian Roberts, Ed Louis, John Morrissey and Elinor Thompson

Chair : Ed Louis

From gene to pathway to genome engineering

10:00 - 10:30

From gene to pathway to genome engineering

Innovative routes to monoterpene hydrocarbons and their derivatives

10:30 - 11:00

Innovative routes to monoterpene hydrocarbons and their derivatives

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

Offered paper - Florine and norine: powerful tools for in silico genome mining leading to discovery of novel nonribosomal peptides

11:30 - 11:45

Offered paper - Florine and norine: powerful tools for in silico genome mining leading to discovery of novel nonribosomal peptides

Offered paper - Discovering novel lantibiotics through bacterial genome mining and proteomics

11:45 - 12:00

Offered paper - Discovering novel lantibiotics through bacterial genome mining and proteomics

Engineering yeast: Synthetic modularity at the gene, circuit, pathway and genome level

12:00 - 12:30

Engineering yeast: Synthetic modularity at the gene, circuit, pathway and genome level

Diversification of natural and non-natural products using engineered biosynthetic pathways and enzymes

12:30 - 13:00

Diversification of natural and non-natural products using engineered biosynthetic pathways and enzymes

Virus workshop: DNA viruses

This workshop will include abstracts on aspects of DNA virology. The workshop will be structured around a typical life-cycle of these viruses, starting with pathogenesis to focus the audience on the diversity of diseases they cause. The session will then move on to cover virus entry and uncoating, genome replication, particle structure, assembly and egress. Both human and animal pathogens will be covered, including the opportunity for clinicians to present studies on ongoing outbreaks or epidemiological studies. The host response to infection will be covered, for example the acquired immune responses, together with vaccine or antiviral-based treatments or therapies that can be used to combat infection.

ORGANISERS

Gill Elliott, Jo Parish, James Stewart and Colin Crump

Chair : James Stewart

Offered paper - A systematic screen of the entire human cytomegalovirus genome for novel NK cell immunomodulators

10:00 - 10:12

Offered paper - A systematic screen of the entire human cytomegalovirus genome for novel NK cell immunomodulators

Offered paper - Mechanisms of immune modulation by vaccinia virus protein C16

10:12 - 10:24

Offered paper - Mechanisms of immune modulation by vaccinia virus protein C16

Offered paper - Characterisation of epitope-specific humoral responses to human cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in solid organ transplant recipient candidates

10:24 - 10:36

Offered paper - Characterisation of epitope-specific humoral responses to human cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in solid organ transplant recipient candidates

Offered paper - Identification of five NK cell evasion funcations in a single HCMV gene family

10:36 - 10:48

Offered paper - Identification of five NK cell evasion funcations in a single HCMV gene family

Offered paper - Characterisation of a non-lytic release mechanism of BK polyomavirus from infected cells

10:48 - 11:00

Offered paper - Characterisation of a non-lytic release mechanism of BK polyomavirus from infected cells

Offered paper - Sequencing human cytomegalovirus genomes directly from clinical material

11:00 - 11:12

Offered paper - Sequencing human cytomegalovirus genomes directly from clinical material

Offered paper

11:12 - 11:24

Offered paper

Offered paper - Hepatitis B: a DNA virus that assembles using a mechanism from an RNA virus

11:24 - 11:36

Offered paper - Hepatitis B: a DNA virus that assembles using a mechanism from an RNA virus

Refreshments and exhibition

11:36 - 12:06

Refreshments and exhibition

Chair : Gill Elliott

Offered paper - Herpes simplex virus-1 proteins UL7 and UL51: cellular localisation and role during virion assembly

12:06 - 12:18

Offered paper - Herpes simplex virus-1 proteins UL7 and UL51: cellular localisation and role during virion assembly

Offered paper - Systematic mapping of poxvirus subviral structure using quantitative proteomics and super-resolution microscopy

12:18 - 12:30

Offered paper - Systematic mapping of poxvirus subviral structure using quantitative proteomics and super-resolution microscopy

Offered paper - The role of retrograde transport in vaccinia virus replication

12:30 - 12:42

Offered paper - The role of retrograde transport in vaccinia virus replication

Offered paper - Understanding the mechanisms of HSV-1 egress and release from cells

12:42 - 12:54

Offered paper - Understanding the mechanisms of HSV-1 egress and release from cells

Offered paper - HSV1 lacking VP22 replicates and spreads in primary human fibroblasts without producing cytopathic effect

12:54 - 13:00

Offered paper - HSV1 lacking VP22 replicates and spreads in primary human fibroblasts without producing cytopathic effect

Virus workshop: Positive strand RNA viruses

This workshop will include abstracts on aspects of positive strand RNA virology. The workshop will be structured around a typical life-cycle of these viruses, starting with pathogenesis to focus the audience on the diversity of diseases they cause. The session will then move on to cover virus entry and uncoating, genome replication, particle structure, assembly and egress. Both human and animal pathogens will be covered, including the opportunity for clinicians to present studies on ongoing outbreaks or epidemiological studies. The host response to infection will be covered, for example the acquired immune responses, together with vaccine or antiviral-based treatments or therapies that can be used to combat infection.

ORGANISERS

David Evans, Adrian Fox and Erica Bickerton

Chair : David Evans and Erica Bickerton

Offered paper - Identification of novel cis- and trans-activities of FMDV 3Dpol necessary for the formation of viral RNA replication complexes

10:00 - 10:12

Offered paper - Identification of novel cis- and trans-activities of FMDV 3Dpol necessary for the formation of viral RNA replication complexes

Offered paper - IBV accessory protein 3a, dsRNA and innate immune evasion

10:12 - 10:24

Offered paper - IBV accessory protein 3a, dsRNA and innate immune evasion

Offered paper - HCV genotype 3 modulation of host cell metabolism pathways and implication in disease progression

10:24 - 10:36

Offered paper - HCV genotype 3 modulation of host cell metabolism pathways and implication in disease progression

Offered paper - The influence of sequence and RNA structure on recombination in Enteroviruses

10:36 - 10:48

Offered paper - The influence of sequence and RNA structure on recombination in Enteroviruses

Offered paper - Infectious bronchitis virus and the AKT signalling pathway

10:48 - 11:00

Offered paper - Infectious bronchitis virus and the AKT signalling pathway

Offered paper - Phylogenetic analysis and evolutionary history of louping ill virus, a neglected pathogen of sheep & grouse in Britain

11:00 - 11:12

Offered paper - Phylogenetic analysis and evolutionary history of louping ill virus, a neglected pathogen of sheep & grouse in Britain

Offered paper - Mutational analysis and evolutionary history of louping ill virus, a neglected pathogen of sheep and grouse in Britain

11:12 - 11:24

Offered paper - Mutational analysis and evolutionary history of louping ill virus, a neglected pathogen of sheep and grouse in Britain

Refreshments and exhibition

11:24 - 11:54

Refreshments and exhibition

Chair : Erica Bickerton and David Evans

Offered paper - Next generation sequencing reveals new Southern African Territories genotypes bringing us closer to understanding the history of foot-and-mouth disease virus in Africa

11:54 - 12:06

Offered paper - Next generation sequencing reveals new Southern African Territories genotypes bringing us closer to understanding the history of foot-and-mouth disease virus in Africa

Offered paper - Stabilising attenuating mutations in poliovaccines against loss through recombination

12:06 - 12:18

Offered paper - Stabilising attenuating mutations in poliovaccines against loss through recombination

Offered paper - Is that a sphingosine in your pocket or are you just happy to see me? The role of the pocket factor in Enterovirus uncoating and capsid stability

12:18 - 12:30

Offered paper - Is that a sphingosine in your pocket or are you just happy to see me? The role of the pocket factor in Enterovirus uncoating and capsid stability

Offered paper - Follicular dendritic cell: a key player in the pathogenesis of foot-and-mouth disease virus

12:30 - 12:42

Offered paper - Follicular dendritic cell: a key player in the pathogenesis of foot-and-mouth disease virus

Offered paper - Investigating the hepatitis C virus replication complex using super-resolution microscopy

12:42 - 12:54

Offered paper - Investigating the hepatitis C virus replication complex using super-resolution microscopy

Virus workshop: Restriction factors

This workshop will include abstracts on aspects of restriction factor biology including constitutively expressed and interferon-induced host factors. We wish to fully explore the complexities of restriction factor function and the countermeasures employed by viruses. Depending upon submissions we will cover host restriction to virus entry and uncoating followed by genome replication and, where relevant, integration. The session will then move on to cover virus genome editing and host strategies to prevent virion packaging and release. Evasion strategies of human and animal pathogens will be covered. 

ORGANISERS

Alain Kohl and Andrew MacDonald

Chair : Alain Kohl

Offered paper - Examining the interplay between the human innate immune system and the non-structural protein (NSs) of emerging tick-borne phleboviruses

10:00 - 10:12

Offered paper - Examining the interplay between the human innate immune system and the non-structural protein (NSs) of emerging tick-borne phleboviruses

Offered paper - TRIM22 restricts influenza A virus as part of an intrinsic antiviral defence

10:12 - 10:24

Offered paper - TRIM22 restricts influenza A virus as part of an intrinsic antiviral defence

Offered paper - The interferon-stimulated gene Ly6E restricts influenza A replication

10:24 - 10:36

Offered paper - The interferon-stimulated gene Ly6E restricts influenza A replication

Offered paper - IFITM3 restricts virus-induced pathogenesis by regulating myeloid cell production of interleukin-6

10:36 - 10:48

Offered paper - IFITM3 restricts virus-induced pathogenesis by regulating myeloid cell production of interleukin-6

Offered paper - Avian IFITMs: restricting avian viral infection

10:48 - 11:00

Offered paper - Avian IFITMs: restricting avian viral infection

Offered paper - Neutralising potency of the innate pattern recognition receptors L-ficolin and H-ficolin against hepatitis C virus and Ebola virus infection

11:00 - 11:12

Offered paper - Neutralising potency of the innate pattern recognition receptors L-ficolin and H-ficolin against hepatitis C virus and Ebola virus infection

Offered paper - Characterising retroviral restriction by TRIM proteins

11:12 - 11:24

Offered paper - Characterising retroviral restriction by TRIM proteins

Refreshments and exhibition

11:24 - 11:54

Refreshments and exhibition

Chair : Andrew MacDonald

Offered paper - Functional characterisation of TMEM156; one of the most highly induced interferon stimulated genes in primary porcine cells

11:54 - 12:06

Offered paper - Functional characterisation of TMEM156; one of the most highly induced interferon stimulated genes in primary porcine cells

Offered paper - Interplay between hepatitis C virus and the circadian clock

12:06 - 12:18

Offered paper - Interplay between hepatitis C virus and the circadian clock

Offered paper - Viral targeting reveals the positive role of ubiquitin specific peptidase 7 (USP7) in the interferon response

12:18 - 12:30

Offered paper - Viral targeting reveals the positive role of ubiquitin specific peptidase 7 (USP7) in the interferon response

Offered paper - Inhibition of retroviral infection by SAMHD1 through dNTP degradation requires stable tetramer formation

12:30 - 12:42

Offered paper - Inhibition of retroviral infection by SAMHD1 through dNTP degradation requires stable tetramer formation

Offered paper - Innate immunity to arboviruses at cutaneous inoculation sites

12:42 - 12:54

Offered paper - Innate immunity to arboviruses at cutaneous inoculation sites

Virus workshop: Viral haemorrhagic fevers

This workshop will include abstracts on aspect of viral haemorrhagic fevers and the workshop will be structured around a typical life-cycle of the viruses that cause these diseases, covering their pathogenesis, virus entry and uncoating, genome replication, particle structure, assembly and egress. There will be an opportunity for clinicians to present studies on ongoing outbreaks, epidemiological studies and diagnostics. The host response to infection will be covered, for example the acquired immune responses, together with vaccine or antiviral-based treatments or therapies being developed to combat infection.

ORGANISERS

Stephen Griffin, Alain Kohl and David Evans

Chair : Stephen Griffin

Offered paper - Use of an Ebola transcription- and replication-competent virus-like particle (trVLP) system to screen for antiviral interferon-stimulated genes

10:00 - 10:12

Offered paper - Use of an Ebola transcription- and replication-competent virus-like particle (trVLP) system to screen for antiviral interferon-stimulated genes

Offered paper - Production of lentiviral particles containing Ebola virus RNA as reference materials for nucleic acid technology-based assays

10:12 - 10:24

Offered paper - Production of lentiviral particles containing Ebola virus RNA as reference materials for nucleic acid technology-based assays

Offered paper - Reference materials for Ebolavirus diagnosis and immune respone analysis

10:24 - 10:36

Offered paper - Reference materials for Ebolavirus diagnosis and immune respone analysis

Offered paper - The nucleoprotein of Ebola-Makona interacts with HSP70 to promote protein stability

10:36 - 10:48

Offered paper - The nucleoprotein of Ebola-Makona interacts with HSP70 to promote protein stability

Refreshments and exhibition

10:48 - 11:18

Refreshments and exhibition

Chair : Stephen Griffin

Offered paper - Elucidating cellular expression changes induced by infection with the Ebola virus Makona strain

11:18 - 11:30

Offered paper - Elucidating cellular expression changes induced by infection with the Ebola virus Makona strain

Offered paper - Tracking naturally acquired immunity to Ebola virus Ziare (EBOV) infection in survivors of the 2014–15 West Africa outbreak

11:30 - 11:42

Offered paper - Tracking naturally acquired immunity to Ebola virus Ziare (EBOV) infection in survivors of the 2014–15 West Africa outbreak

Offered paper - Lujo virus and LCMV nucleoproteins enhance translation of viral-like mRNA through translation factor recruitment suggesting a novel method for mRNA circularisation

11:42 - 11:54

Offered paper - Lujo virus and LCMV nucleoproteins enhance translation of viral-like mRNA through translation factor recruitment suggesting a novel method for mRNA circularisation

Offered paper - Stalling to a halt – transcriptome analysis of Puumala virus infected cells

11:54 - 12:06

Offered paper - Stalling to a halt – transcriptome analysis of Puumala virus infected cells

Offered paper - Exploiting the reverse genetics system for severe fever with thrombocytopenia syndrome virus to study Phlebovirus tropism

12:06 - 12:18

Offered paper - Exploiting the reverse genetics system for severe fever with thrombocytopenia syndrome virus to study Phlebovirus tropism

Offered paper - Use of Ebola pseudoparticles to interrogate the impact of Ebola virus glycoprotein evolution during the West African outbreak

12:18 - 12:30

Offered paper - Use of Ebola pseudoparticles to interrogate the impact of Ebola virus glycoprotein evolution during the West African outbreak

Offered paper - Differential gene expression analysis of acute Ebola virus patients with fatal or non-fatal infections

12:30 - 12:42

Offered paper - Differential gene expression analysis of acute Ebola virus patients with fatal or non-fatal infections

Offered paper - Production of an antigen reference material for Ebola virus diagnostics

12:42 - 12:54

Offered paper - Production of an antigen reference material for Ebola virus diagnostics

Wednesday 23 March, Afternoon

iGEM poster exhibition

13:00 - 14:30

iGEM poster exhibition

Live at Lunch: International Committee on Taxonomy of Viruses

13:00 - 14:30

Live at Lunch: International Committee on Taxonomy of Viruses

Lunch, exhibition & poster viewing

13:00 - 14:30

Lunch, exhibition & poster viewing

The model microbe – how far can it go?

For many years, researchers have turned to simple and experimentally amenable microbial organisms to understand the basic workings of the cell. In recent years the range of organisms used in research has expanded in parallel with the huge developments in genome sequencing and molecular biology. As the genetic basis of many human diseases is becoming clear, molecular studies in simplified model systems can be used to determine gene function and give insights into disease pathology. This timely and widely relevant session will highlight and promote the systems and experimental approaches being used today.

ORGANISERS

Jason King, Elinor Thompson and Gareth Bloomfield

Offered paper - Modelling of iron metabolism within the metabolic network of yeast

13:00 - 13:15

Offered paper - Modelling of iron metabolism within the metabolic network of yeast

Offered paper - Regulation of macropinocytosis in Dictyostelium

13:15 - 13:30

Offered paper - Regulation of macropinocytosis in Dictyostelium

Chair : Elinor Thompson

From amoeba to bedside: Epilepsy research in the social amoeba Dictyostelium

14:30 - 15:00

From amoeba to bedside: Epilepsy research in the social amoeba Dictyostelium

Gene expression in a remnant chloroplast: The plasmodium apicoplast

15:00 - 15:30

Gene expression in a remnant chloroplast: The plasmodium apicoplast

Circadian clock research in the pico-eukaryote Ostreococcus tauri: A bacterial-sized cell with a yeast-sized genome

15:30 - 16:00

Circadian clock research in the pico-eukaryote Ostreococcus tauri: A bacterial-sized cell with a yeast-sized genome

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Chair : Jason King

Divergence, adaptation and loss of genome maintenance pathways in trypanosomatids

16:30 - 17:00

Divergence, adaptation and loss of genome maintenance pathways in trypanosomatids

Genome surveillance in neurospora

17:00 - 17:30

Genome surveillance in neurospora

Clinical Virology Network

This workshop will involve a range of clinical virology cases or short papers which relate to studies relevant to clinical virology network. Different aspects of clinical virology that will be covered include: differential diagnosis of encephalitis, management of hepatitis, diversity of rotavirus sequences, and diagnosis of respiratory infections.

ORGANISERS

Miren Iturriza-Gomara and Matthew Donati

Chair : Stephen Winchester

Human animal infections and risk surveillance (HAIRS) and emerging infection risks to human health

14:30 - 15:00

Human animal infections and risk surveillance (HAIRS) and emerging infection risks to human health

The management of patients with herpes simplex encephalitis – is there a case for steroids?

15:00 - 15:30

The management of patients with herpes simplex encephalitis – is there a case for steroids?

Refreshments and exhibition

15:30 - 16:00

Refreshments and exhibition

Cats, rats and bats: Rabies clinical service case histories and management issues

16:00 - 16:30

Cats, rats and bats: Rabies clinical service case histories and management issues

Insights from within: Current understanding of microbial interactions with insects

Understanding of critical interactions of insects with microbes has made great progress in recent years, fuelled by methodological advances in (ecological) genomics and analytical techniques. This symposium highlights current advances in insect microbiology at different scales, from molecular insights into insect-microbe dependencies to recognition and application of microbial intervention mechanisms that affect insect behaviour and transmission of pathogens and the dynamics of insect microbiome assembly.

ORGANISERS

Geertje van Keulen, Ryan Seipke, Thorsten Allers and Miranda Whitten

Chair : Ryan Seipke

Genomics of the distinctive gut community of honey bees

14:30 - 15:00

Genomics of the distinctive gut community of honey bees

The DrosophilaSpiroplasma interaction as a model to dissect the molecular mechanisms underlying insect endosymbiosis

15:00 - 15:30

The DrosophilaSpiroplasma interaction as a model to dissect the molecular mechanisms underlying insect endosymbiosis

Development of RNAi delivery tools using gut symbionts of blood-and sap-feeding insects

15:30 - 16:00

Development of RNAi delivery tools using gut symbionts of blood-and sap-feeding insects

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Chair : Thorsten Allers

Molecular dissection of phytoplasma modulation of plant hosts and insect vectors

16:30 - 17:00

Molecular dissection of phytoplasma modulation of plant hosts and insect vectors

Regulation and biosynthesis of natural products produced by insect-associated Actinomycetes

17:00 - 17:30

Regulation and biosynthesis of natural products produced by insect-associated Actinomycetes

Offered paper - Genomic analyses of bee-associated Wolbachia reveal a recent biotin operon transfer and enable the timing of Wolbachia diversification

17:30 - 17:45

Offered paper - Genomic analyses of bee-associated Wolbachia reveal a recent biotin operon transfer and enable the timing of Wolbachia diversification

Offered paper - New insights into interactions between entomopathogenic fungi and insect hosts

17:45 - 18:00

Offered paper - New insights into interactions between entomopathogenic fungi and insect hosts

Mining microbial diversity for pleasure and profit

Microbes are wonderful chemists and their ability to produce pleasurable flavours and fragrances in foods and drinks has been exploited for thousands of years. Technological progress is now allowing us to extend the uses of yeasts and bacteria from things like brewing and cheese-making all the way to making renewable chemicals to reduce the rate of climate change. This session will bring together university and industry scientists to showcase the extraordinary variety of Nature’s microbial treasure trove and demonstrate how advances in genome mining and synthetic biology are unlocking this natural diversity to an ever-increasing extent. The benefits to society of re-discovering traditional foods and flavours as well as building new businesses harnessing the power of microbiology are many and an exciting ‘taste’ of future possibilities will permeate the meeting.

ORGANISERS

Ian Roberts, Ed Louis, John Morrissey and Elinor Thompson

Chair : John Morrissey

Using baker's yeast for production of sustainable ingredients in health, wellness and nutrition

14:30 - 15:00

Using baker's yeast for production of sustainable ingredients in health, wellness and nutrition

Exploiting microbial diversity for the redesign of bacterial organelles

15:00 - 15:30

Exploiting microbial diversity for the redesign of bacterial organelles

Refreshments and exhibition

15:30 - 16:00

Refreshments and exhibition

Chair : Ian Roberts

Offered paper - Promoting microbiology education through the iGEM synthetic biology competition

16:00 - 16:15

Offered paper - Promoting microbiology education through the iGEM synthetic biology competition

Offered paper - GlasGlow: Engineering glow in the dark biology

16:15 - 16:30

Offered paper - GlasGlow: Engineering glow in the dark biology

Offered paper - AlcoPatch: Synthetic biology tools as lifestyle accessories

16:30 - 16:45

Offered paper - AlcoPatch: Synthetic biology tools as lifestyle accessories

Engineering yeast to produce plant flavours

16:45 - 17:15

Engineering yeast to produce plant flavours

Microbial metabolic engineering to deliver better products for a better planet

17:15 - 17:45

Microbial metabolic engineering to deliver better products for a better planet

Prokaryotic cell biology forum

This forum will consider work on all fundamental aspects of the physiology, biochemistry and structure of prokaryotic cells. This includes metabolism, synthesis and transport of macromolecules, membrane transport of ions and small molecules, the cell cycle, cell architecture, differentiation, sensing and cellular responses, signalling and communication, bioenergetics and the structure, and function and mode of action of microbial factors. Papers on the engineering and applications of microbes will also be welcome.

ORGANISERS

Steve Michell and Mark Webber

Chair : Stephen Michell

Protein transport by the bacterial Tat pathway

14:30 - 15:00

Protein transport by the bacterial Tat pathway

Offered paper - Metal storage in bacterial and archaeal iron megastores: half ferritin, half virus

15:00 - 15:15

Offered paper - Metal storage in bacterial and archaeal iron megastores: half ferritin, half virus

Offered paper - Starvation survival of Bacillus subtilis without sporulation

15:15 - 15:30

Offered paper - Starvation survival of Bacillus subtilis without sporulation

Offered paper - Structure of the crystalline native Clostridium difficile S-layer

15:30 - 15:45

Offered paper - Structure of the crystalline native Clostridium difficile S-layer

Offered paper - What are the benefits of aging for bacteria and what is the evidence?

15:45 - 16:00

Offered paper - What are the benefits of aging for bacteria and what is the evidence?

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Chair : Mark Webber

Offered paper - Plasmid-induced filamentation in Salmonella used in bacteria mediated cancer research

16:30 - 16:45

Offered paper - Plasmid-induced filamentation in Salmonella used in bacteria mediated cancer research

Offered paper - Functional analysis of an unusual type IV pilus in the Gram-positive Streptococcus sanguinis

16:45 - 17:00

Offered paper - Functional analysis of an unusual type IV pilus in the Gram-positive Streptococcus sanguinis

Offered paper - Promoting stable polyphosphate accumulation in E. coli using recombinant bacterial microcompartment-directed polyphosphate kinase

17:00 - 17:15

Offered paper - Promoting stable polyphosphate accumulation in E. coli using recombinant bacterial microcompartment-directed polyphosphate kinase

Offered paper - Investigating YecA, a potential component of the Sec machinery of Escherichia coli

17:15 - 17:30

Offered paper - Investigating YecA, a potential component of the Sec machinery of Escherichia coli

Offered paper - Localising autotransporter EspC during secretion to identify potential targets for novel antimicrobials

17:30 - 17:45

Offered paper - Localising autotransporter EspC during secretion to identify potential targets for novel antimicrobials

Prokaryotic genetics forum

Offered papers on all aspects of the genes and genomes of prokaryotes and their mobile elements will be considered, including their sequencing, transcription, translation, regulation, chromosome dynamics, gene transfer, population genetics and evolution, taxonomy and systematics, comparative genomics, metagenomics, bioinformatics, and synthetic biology.

ORGANISERS

Lori Snyder and Thorsten Allers

Chair : Thorsten Allers

Microbial genomics and beyond

14:30 - 15:00

Microbial genomics and beyond

Offered paper - Prevalence and molecular types of Clostridium difficile isolates from faecal specimens of patients in a tertiary care centre

15:00 - 15:15

Offered paper - Prevalence and molecular types of Clostridium difficile isolates from faecal specimens of patients in a tertiary care centre

Offered paper - Emergence of host-adapted Salmonella enteritidis through rapid evolution in an immunocompromised host

15:15 - 15:30

Offered paper - Emergence of host-adapted Salmonella enteritidis through rapid evolution in an immunocompromised host

Offered paper - Bacillus subtilis with a linear chromosome

15:30 - 15:45

Offered paper - Bacillus subtilis with a linear chromosome

Offered paper - How variable is variability: how different are the phase variable genes of Campylobacter strains?

15:45 - 16:00

Offered paper - How variable is variability: how different are the phase variable genes of Campylobacter strains?

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Chair : Lori Snyder

Offered paper - Gene mobility promotes the persistence of a bacterial social trait

16:30 - 16:45

Offered paper - Gene mobility promotes the persistence of a bacterial social trait

Offered paper - Source-sink plasmid transfer dynamics maintain gene mobility and facilitate interspecific gene transfer in soil bacterial communities

16:45 - 17:00

Offered paper - Source-sink plasmid transfer dynamics maintain gene mobility and facilitate interspecific gene transfer in soil bacterial communities

Offered paper - Enterococcus faecium genome dynamics during long-term patient gut colonisation

17:00 - 17:15

Offered paper - Enterococcus faecium genome dynamics during long-term patient gut colonisation

Offered paper - A longitudinal study of elderly patients identifies dynamic bacterial and host responses to long-term Escherichia coli colonisation of the bladder

17:15 - 17:30

Offered paper - A longitudinal study of elderly patients identifies dynamic bacterial and host responses to long-term Escherichia coli colonisation of the bladder

Offered paper - Sequencing a piece of history: Complete genome sequence of the first Escherichia coli isolate

17:30 - 17:45

Offered paper - Sequencing a piece of history: Complete genome sequence of the first Escherichia coli isolate

Virus workshop: DNA viruses

This workshop will include abstracts on aspects of DNA virology. The workshop will be structured around a typical life-cycle of these viruses, starting with pathogenesis to focus the audience on the diversity of diseases they cause. The session will then move on to cover virus entry and uncoating, genome replication, particle structure, assembly and egress. Both human and animal pathogens will be covered, including the opportunity for clinicians to present studies on ongoing outbreaks or epidemiological studies. The host response to infection will be covered, for example the acquired immune responses, together with vaccine or antiviral-based treatments or therapies that can be used to combat infection.

ORGANISERS

Gill Elliott, Jo Parish, James Stewart and Colin Crump

Chair : Colin Crump

Offered paper - The expression of the human cytomegalovirus US28 gene is necessary for the establishment of latency in early myeloid cells

14:30 - 14:42

Offered paper - The expression of the human cytomegalovirus US28 gene is necessary for the establishment of latency in early myeloid cells

Offered paper - In vivo association of HPV16 E2 with Rad50-interacting protein 1 (Rint1) and its role in viral genome replication

14:42 - 14:54

Offered paper - In vivo association of HPV16 E2 with Rad50-interacting protein 1 (Rint1) and its role in viral genome replication

Offered paper - The human cytomegalovirus IE1 protein rewires STAT3 to STAT1 signalling tempering viral replication

14:54 - 15:06

Offered paper - The human cytomegalovirus IE1 protein rewires STAT3 to STAT1 signalling tempering viral replication

Offered paper - Use of chemical biology to identify cellular protein kinases involved in histone phosphorylation during human cytomegalovirus replication

15:06 - 15:18

Offered paper - Use of chemical biology to identify cellular protein kinases involved in histone phosphorylation during human cytomegalovirus replication

Offered paper - Human cytomegalovirus latency-associated protein LUNA regulates latent viral gene expression by disrupting cellular PML bodies

15:18 - 15:30

Offered paper - Human cytomegalovirus latency-associated protein LUNA regulates latent viral gene expression by disrupting cellular PML bodies

Offered paper - Nuclear pore complex remodelling in Kaposi's sarcoma-associated herpesvirus lytic infection

15:30 - 15:42

Offered paper - Nuclear pore complex remodelling in Kaposi's sarcoma-associated herpesvirus lytic infection

Offered paper - CTCF regulates differentiation-dependent human papillomavirus (HPV) gene expression

15:42 - 15:54

Offered paper - CTCF regulates differentiation-dependent human papillomavirus (HPV) gene expression

Refreshments and exhibition

15:54 - 16:24

Refreshments and exhibition

Chair : Jo Parish

Offered paper - Spatial analysis of nascent protein synthesis and association with PML bodies during HSV infection revealed by click chemistry

16:24 - 16:36

Offered paper - Spatial analysis of nascent protein synthesis and association with PML bodies during HSV infection revealed by click chemistry

Offered paper - Low oxygen regulates hepatitis B virus transcription

16:36 - 16:48

Offered paper - Low oxygen regulates hepatitis B virus transcription

Offered paper - The relationship between Merkel cell polyomavirus small T (ST) antigen and cell adhesion molecules – implication for metastatis

16:48 - 17:00

Offered paper - The relationship between Merkel cell polyomavirus small T (ST) antigen and cell adhesion molecules – implication for metastatis

Offered paper - Next generation sequencing reveals novel cellular targets for Merkel cell polyomavirus miRNA

17:00 - 17:12

Offered paper - Next generation sequencing reveals novel cellular targets for Merkel cell polyomavirus miRNA

Offered paper - Cell cycle regulation through translational control of RGC-32 in EBV immortalised B cells

17:12 - 17:24

Offered paper - Cell cycle regulation through translational control of RGC-32 in EBV immortalised B cells

Offered paper - Characterisation of the antiviral activity of a chloride ion channel inhibitor on human cytomegalovirus

17:24 - 17:36

Offered paper - Characterisation of the antiviral activity of a chloride ion channel inhibitor on human cytomegalovirus

Offered paper - Novel non-immune suppresive analogues of cyclosporine A promote a post-DNA replication defect in human cytomegalovirus replication

17:36 - 17:48

Offered paper - Novel non-immune suppresive analogues of cyclosporine A promote a post-DNA replication defect in human cytomegalovirus replication

Offered paper - Dissection of the molecular determinants and pathways involved in Hepatitis B virus (HBV) entry into hepatocytes

17:48 - 18:00

Offered paper - Dissection of the molecular determinants and pathways involved in Hepatitis B virus (HBV) entry into hepatocytes

Virus workshop: Negative strand RNA viruses

This workshop will include abstracts on aspects of negative strand RNA virology. Depending upon submissions the workshop will be structured around a typical life-cycle of these viruses, starting with pathogenesis to focus the audience on the diversity of diseases they cause. The session will then move on to cover virus entry and uncoating, genome replication, particle structure, assembly and egress. Both human and animal pathogens will be covered, including the opportunity for clinicians to present studies on ongoing outbreaks or epidemiological studies. The host response to infection will be covered, for example the acquired immune responses, together with vaccine or antiviral-based treatments or therapies that can be used to combat infection.

ORGANISERS

Wendy Barclay and Silke Schepelmann

Chair : Wendy Barclay

Offered paper - Avian influenza: can antigenic drift lead to an augmented zoonotic potential?

14:30 - 14:42

Offered paper - Avian influenza: can antigenic drift lead to an augmented zoonotic potential?

Offered paper - Developing a PP7-based system to capture proteins involved in viral RNA recognition by RLRs

14:42 - 14:54

Offered paper - Developing a PP7-based system to capture proteins involved in viral RNA recognition by RLRs

Offered paper - The role of influenza A virus ribonucleoprotein structure in interferon induction

14:54 - 15:06

Offered paper - The role of influenza A virus ribonucleoprotein structure in interferon induction

Offered paper - Identification of sequence polymorphisms in segment 3 of H9N2 avian influenza viruses that affect PA-X activity

15:06 - 15:18

Offered paper - Identification of sequence polymorphisms in segment 3 of H9N2 avian influenza viruses that affect PA-X activity

Offered paper - The influenza A virus PB1-F2 protein enhances virus transmission in chickens

15:18 - 15:30

Offered paper - The influenza A virus PB1-F2 protein enhances virus transmission in chickens

Offered paper - Why are potassium channels required for the multiplication of bunyaviruses?

15:30 - 15:42

Offered paper - Why are potassium channels required for the multiplication of bunyaviruses?

Offered paper - The potential for novel combination therapies targeting the M2 ion channel of pandemic influenza viruses

15:42 - 15:54

Offered paper - The potential for novel combination therapies targeting the M2 ion channel of pandemic influenza viruses

Refreshments and exhibition

15:54 - 16:24

Refreshments and exhibition

Chair : Silke Schepelmann

Offered paper - In vitro and in vivo growth alter the population dynamic and properties of a Jeryl Lynn mumps vaccine

16:24 - 16:36

Offered paper - In vitro and in vivo growth alter the population dynamic and properties of a Jeryl Lynn mumps vaccine

Offered paper - Subversion of autophagy by influenza A virus M2 protein

16:36 - 16:48

Offered paper - Subversion of autophagy by influenza A virus M2 protein

Offered paper - Morphogenesis of respiratory syncytial virus in human primary nasal ciliated epithelial cells

16:48 - 17:00

Offered paper - Morphogenesis of respiratory syncytial virus in human primary nasal ciliated epithelial cells

Offered paper - A Staphylococcus aureus secreted protein enhances influenza A virus replication in vitro

17:00 - 17:12

Offered paper - A Staphylococcus aureus secreted protein enhances influenza A virus replication in vitro

Offered paper - BPIFA1/SPLUNC1 restricts influenza A virus infection in the host by influencing the adaptive immune response

17:12 - 17:24

Offered paper - BPIFA1/SPLUNC1 restricts influenza A virus infection in the host by influencing the adaptive immune response

Offered paper - Identification of the genetic signatures in the haemagglutinin (HA) protein that control the stability of live attenuated influenza vaccines

17:24 - 17:36

Offered paper - Identification of the genetic signatures in the haemagglutinin (HA) protein that control the stability of live attenuated influenza vaccines

Offered paper - The contribution of specific haemagglutinin mutations to equine influenza vaccine breakdown

17:36 - 17:48

Offered paper - The contribution of specific haemagglutinin mutations to equine influenza vaccine breakdown

Virus workshop: Positive strand viruses, double stranded RNA viruses and plant viruses

This workshop will include abstracts on aspects of the biology of positive strand RNA, double stranded RNA or plant viruses. Depending upon submissions the workshop will be structured around a typical life-cycle of these viruses, starting with pathogenesis to focus the audience on the diversity of diseases they cause. The session will then move on to cover virus entry and uncoating, genome replication, particle structure, assembly and egress. Both human, animal and plant pathogens will be covered as will the host responses to infection, for example the acquired immune or RNAi responses, together with vaccine or antiviral-based treatments or therapies that can be used to combat infection.

ORGANISERS

David Evans, Adrian Fox and Erica Bickerton

Chair : Adrian Fox and Alain Kohl

Offered paper - Bluetongue virus expresses a small protein from a second open reading frame in segment 10

14:30 - 14:42

Offered paper - Bluetongue virus expresses a small protein from a second open reading frame in segment 10

Offered paper - Analysis of mutations in domain I of the hepatitis C virus non-structural NS5A protein

14:42 - 14:54

Offered paper - Analysis of mutations in domain I of the hepatitis C virus non-structural NS5A protein

Offered paper - Bluetongue virus infection of bovine monocytes is altered in the presence of Culicoides sonorensis salivary proteins

14:54 - 15:06

Offered paper - Bluetongue virus infection of bovine monocytes is altered in the presence of Culicoides sonorensis salivary proteins

Offered paper - Characterisation of over 50 novel, infectious, chimeric hepatitis C virus clones incorporating genotype 1, 2 and 3 patient-derived glycoproteins

15:06 - 15:18

Offered paper - Characterisation of over 50 novel, infectious, chimeric hepatitis C virus clones incorporating genotype 1, 2 and 3 patient-derived glycoproteins

Offered paper - Development of rationally attenuated live vaccines for effective control of infectious bronchitis

15:18 - 15:30

Offered paper - Development of rationally attenuated live vaccines for effective control of infectious bronchitis

Offered paper - Detection of undefined RNA secondary structure within the non-structural region of the FMDV genome

15:30 - 15:42

Offered paper - Detection of undefined RNA secondary structure within the non-structural region of the FMDV genome

Offered paper - The fourth non-structural protein of African horse sickness virus

15:42 - 15:54

Offered paper - The fourth non-structural protein of African horse sickness virus

Refreshments and exhibition

15:54 - 16:24

Refreshments and exhibition

Chair : Adrian Fox and Alain Kohl

Offered paper - Isolation and analysis of recombinants from mixed virus infections using next generation sequencing (NGS) and bioinformatics

16:24 - 16:36

Offered paper - Isolation and analysis of recombinants from mixed virus infections using next generation sequencing (NGS) and bioinformatics

Offered paper - Characterisation of genes involved in the propagation failure of bluetongue virus serotype 26 (BTV-26) in Culicoides sonorensis cell line (KC) and adult Culicoides sonorensis midges

16:36 - 16:48

Offered paper - Characterisation of genes involved in the propagation failure of bluetongue virus serotype 26 (BTV-26) in Culicoides sonorensis cell line (KC) and adult Culicoides sonorensis midges

Offered paper - New insights into the honey bee pathogen, deformed wing virus

16:48 - 17:00

Offered paper - New insights into the honey bee pathogen, deformed wing virus

Offered paper - Defining the function of multiple copies of 3B in foot-and-mouth disease virus RNA replication

17:12 - 17:24

Offered paper - Defining the function of multiple copies of 3B in foot-and-mouth disease virus RNA replication

Offered paper - Serial infection of porcine rotavirus through cell lines deficient for innate antiviral mechanisms

17:24 - 17:36

Offered paper - Serial infection of porcine rotavirus through cell lines deficient for innate antiviral mechanisms

Offered paper - Translation of Tulane virus, a novel surrogate for human norovirus

17:36 - 17:48

Offered paper - Translation of Tulane virus, a novel surrogate for human norovirus

Offered paper - 'Trans'-lating the untranslated region: Complementation studies of the FMDV 5' UTR

17:48 - 18:00

Offered paper - 'Trans'-lating the untranslated region: Complementation studies of the FMDV 5' UTR

Virus workshop: Retroviruses

We invite abstracts on any aspect of retrovirus biology. Depending upon submissions the workshop will be structured around a typical life-cycle of these viruses, starting with pathogenesis to focus the audience on the diversity of diseases they cause. The session will then move on to cover virus entry and uncoating, genome replication, particle structure, assembly and egress. Both human and animal pathogens will be covered, including the opportunity for clinicians to present studies on ongoing outbreaks or epidemiological studies. The host response to infection will be covered, for example the acquired immune responses, together with vaccine or antiviral-based treatments or therapies that can be used to combat infection.

ORGANISERS

Cathy Adamson and Kate Bishop

Offered oral - Novel restriction factor RNA-associated early-stage anti-viral factor (REAF) inhibits human and simian immunodeficiency viruses

14:30 - 14:42

Offered oral - Novel restriction factor RNA-associated early-stage anti-viral factor (REAF) inhibits human and simian immunodeficiency viruses

Offered oral - Uncoating of HIV-1 capsid is triggered after the first stand transfer of reverse transcription

14:42 - 14:54

Offered oral - Uncoating of HIV-1 capsid is triggered after the first stand transfer of reverse transcription

Offered oral - A novel lentiviral vector model to investigate the mechanism of insertional mutagenesis by aberrant splicing

14:54 - 15:06

Offered oral - A novel lentiviral vector model to investigate the mechanism of insertional mutagenesis by aberrant splicing

Offered oral - A novel cis-acting element affecting HIV replication

15:06 - 15:18

Offered oral - A novel cis-acting element affecting HIV replication

Offered oral - A role for genomic RNA in regulating the maturation of the HIV-1 virion core

15:18 - 15:30

Offered oral - A role for genomic RNA in regulating the maturation of the HIV-1 virion core

Refreshments and exhibition

15:30 - 16:00

Refreshments and exhibition

Offered oral - Characterisation of the expression of novel endogenous retroviruses and immune interactions in a macaque model

16:00 - 16:12

Offered oral - Characterisation of the expression of novel endogenous retroviruses and immune interactions in a macaque model

Offered oral - Dendritic cell bio-marker of protection following vaccination with live attenuated SIV

16:12 - 16:24

Offered oral - Dendritic cell bio-marker of protection following vaccination with live attenuated SIV

Offered oral - European research infrastructures for poverty related diseases (EURIPRED)

16:24 - 16:36

Offered oral - European research infrastructures for poverty related diseases (EURIPRED)

Colworth Prize Lecture: Exploiting new biological targets from a whole-cell phenotypic screening campaign for TB drug discovery

18:10 - 19:00

Colworth Prize Lecture: Exploiting new biological targets from a whole-cell phenotypic screening campaign for TB drug discovery

Poster viewing, drinks & exhibition

19:00 - 21:00

Poster viewing, drinks & exhibition

iGEM poster exhibition

19:15 - 20:15

iGEM poster exhibition

Meet the Speakers

19:30 - 20:30

Meet the Speakers

Science Showoff

20:15 - 22:00

Science Showoff

Thursday 24 March, Morning

Exhibition, morning coffee, tea and pastries, and Close

07:00 - 09:20

Exhibition, morning coffee, tea and pastries, and Close

Novel tools for manipulation of genes and genomes

Genetic manipulation technologies are essential for advances in many areas of biology, from research into fundamental cellular mechanisms to the applied fields of industrial biotechnology and synthetic biology. This session will feature a number of the inventors and pioneers of technologies that have become indispensable for microbiological research and development.

ORGANISERS

Rocky Cranenburgh and Ryan Seipke

Chair : Rocky Cranenburgh

Nucleic acid delivery systems for RNA therapy and gene editing

09:30 - 10:00

Nucleic acid delivery systems for RNA therapy and gene editing

Reading, writing and editing a genome: An emerging frontier in synthetic biology

10:00 - 10:30

Reading, writing and editing a genome: An emerging frontier in synthetic biology

Refreshments and exhibition

10:30 - 11:00

Refreshments and exhibition

Chair : Dave Grainger

Application of genome editing technology in livestock

11:00 - 11:30

Application of genome editing technology in livestock

The use of phage integrases for genome engineering and metabolic pathway assembly

11:30 - 12:00

The use of phage integrases for genome engineering and metabolic pathway assembly

The hostile cell: Intrinsic antiviral immunity – part 2

The innate immune system represents the first line of defence against infection. It consists of a number of constitutively expressed and inducible factors that suppress or prevent virus infection. Some of these are well-characterised, others are still poorly understood. This symposium will highlight the roles of these anti-viral factors in the immune responses of both vertebrate and non-vertebrate species, and discuss the mechanisms by which they create an environment hostile to virus replication. Virus countermeasures to these processes will also be described. The symposium will take place concurrently with the restriction factor workshop, allowing a forum for the exchange of ideas between disparate groups of virologists.

ORGANISERS

Andrew MacDonald and James Stewart

Chair : Andrew MacDonald and David Evans

HIV restriction – striking early

09:30 - 10:00

HIV restriction – striking early

Offered paper - E6 mediated serine phosphorylation of STAT3 is critical for the human papillomavirus lifecycle

10:00 - 10:15

Offered paper - E6 mediated serine phosphorylation of STAT3 is critical for the human papillomavirus lifecycle

The role played by autophagy during viral infection

10:15 - 10:45

The role played by autophagy during viral infection

Refreshments and exhibition

10:45 - 11:15

Refreshments and exhibition

Chair : Andrew MacDonald and David Evans

Viruses transfer the antiviral second messenger cgamp between cells

11:15 - 11:45

Viruses transfer the antiviral second messenger cgamp between cells

The global transcriptional landscape: Small changes, big effects

The role of global regulatory systems in controlling the transcriptional landscape in bacteria has been a cornerstone of modern molecular microbiology. Much of this work has focussed on how regulators such as HNS, two component systems and quorum sensing systems allow bacteria to control expression in response to changes in their environment. Recent methodological advances have opened exciting new avenues in our approach to studying factors that affect the global transcriptional landscape in bacteria. In this symposium we will focus on the interplay between acquisition of genetic material and changes in the global transcriptional profile in bacteria, and how seemingly stochastic processes such as chromosomal position or methylation patterns have a profound effect on the global transcriptional profile and bacterial phenotypes.

ORGANISERS

Lori Snyder, Mark Webber and Alan McNally

Chair : Lori Snyder

Global reprogramming of the Yersinia pseudotuberculosis transcriptional landscape in response to temperature and host signals

09:40 - 10:10

Global reprogramming of the Yersinia pseudotuberculosis transcriptional landscape in response to temperature and host signals

A structural basis for the silencing of foreign DNA by bacteria

10:10 - 10:40

A structural basis for the silencing of foreign DNA by bacteria

Refreshments and exhibition

10:40 - 11:10

Refreshments and exhibition

Chair : Dave Grainger

Offered paper - The global regulatory role of the RNA-binding protein CsrA in Escherichia coli

11:10 - 11:25

Offered paper - The global regulatory role of the RNA-binding protein CsrA in Escherichia coli

Random switching and global expression changes in the pneumococcus

11:25 - 11:55

Random switching and global expression changes in the pneumococcus

Insights from within: Current understanding of microbial interactions with insects

Understanding of critical interactions of insects with microbes has made great progress in recent years, fuelled by methodological advances in (ecological) genomics and analytical techniques. This symposium highlights current advances in insect microbiology at different scales, from molecular insights into insect-microbe dependencies to recognition and application of microbial intervention mechanisms that affect insect behaviour and transmission of pathogens and the dynamics of insect microbiome assembly.

ORGANISERS

Geertje van Keulen, Ryan Seipke, Thorsten Allers and Miranda Whitten

Chair : Miranda Whitten

The role bacterial endosymbionts play in male killing by ladybirds

09:45 - 10:15

The role bacterial endosymbionts play in male killing by ladybirds

Offered paper - Investigating effects of co-infection on endosymbiont function in aphids

10:15 - 10:30

Offered paper - Investigating effects of co-infection on endosymbiont function in aphids

Refreshments and exhibition

10:30 - 11:00

Refreshments and exhibition

Using inherited bacteria as a way to stop mosquitoes from transmitting dengue: The Eliminate Dengue program

11:00 - 11:30

Using inherited bacteria as a way to stop mosquitoes from transmitting dengue: The Eliminate Dengue program

Who’s in there: Gut microbes, sexual behaviour and host fitness in fruitflies

11:30 - 12:00

Who’s in there: Gut microbes, sexual behaviour and host fitness in fruitflies

Lunch, exhibition & poster viewing

12:00 - 13:00

Lunch, exhibition & poster viewing

Thursday 24 March, Afternoon

Insights from within: Current understanding of microbial interactions with insects

Understanding of critical interactions of insects with microbes has made great progress in recent years, fuelled by methodological advances in (ecological) genomics and analytical techniques. This symposium highlights current advances in insect microbiology at different scales, from molecular insights into insect-microbe dependencies to recognition and application of microbial intervention mechanisms that affect insect behaviour and transmission of pathogens and the dynamics of insect microbiome assembly.

ORGANISERS

Geertje van Keulen, Ryan Seipke, Thorsten Allers and Miranda Whitten

Chair : Geertje van Keulen

The greater picture: Evolutionary implications of antimicrobial defenses in beewolves

13:00 - 13:30

The greater picture: Evolutionary implications of antimicrobial defenses in beewolves

Fat flies: How the gut microbiota shapes host energy metabolism

13:30 - 14:00

Fat flies: How the gut microbiota shapes host energy metabolism

Microbiome assembly in leaf-cutter ants

14:00 - 14:30

Microbiome assembly in leaf-cutter ants

Refreshments and exhibition

14:30 - 15:00

Refreshments and exhibition

Chair : Geertje van Keulen

Wolbachia-mediated protection of insect hosts against pathogens

15:00 - 15:30

Wolbachia-mediated protection of insect hosts against pathogens

Offered paper - Drosophila melanogaster gut microbiota: emergent and dependent properties

15:30 - 15:45

Offered paper - Drosophila melanogaster gut microbiota: emergent and dependent properties

Offered oral - Getting around: the evolutionary ecology of host shifts by heritable microbes

15:45 - 16:00

Offered oral - Getting around: the evolutionary ecology of host shifts by heritable microbes

Novel tools for manipulation of genes and genomes

Genetic manipulation technologies are essential for advances in many areas of biology, from research into fundamental cellular mechanisms to the applied fields of industrial biotechnology and synthetic biology. This session will feature a number of the inventors and pioneers of technologies that have become indispensable for microbiological research and development.

ORGANISERS

Rocky Cranenburgh and Ryan Seipke

Chair : Ryan Seipke

ClosTron for genome editing in Clostridium

13:00 - 13:30

ClosTron for genome editing in Clostridium

Structural insight into Cre/loxP recombinase for the engineering of a new specific anti-HIV recombinase

13:30 - 14:00

Structural insight into Cre/loxP recombinase for the engineering of a new specific anti-HIV recombinase

Offered paper - Making mycobacterial steroids for industry

14:00 - 14:15

Offered paper - Making mycobacterial steroids for industry

Offered paper - Large serine integrases for synthetic biology

14:15 - 14:30

Offered paper - Large serine integrases for synthetic biology

Refreshments and exhibition

14:30 - 15:00

Refreshments and exhibition

Chair : Ryan Seipke

Xer-cise & X-mark: Plasmid and chromosome engineering using Xer recombinases

15:00 - 15:30

Xer-cise & X-mark: Plasmid and chromosome engineering using Xer recombinases

Radical recoding of microbial genomes

15:30 - 16:00

Radical recoding of microbial genomes

The global transcriptional landscape: Small changes, big effects

The role of global regulatory systems in controlling the transcriptional landscape in bacteria has been a cornerstone of modern molecular microbiology. Much of this work has focussed on how regulators such as HNS, two component systems and quorum sensing systems allow bacteria to control expression in response to changes in their environment. Recent methodological advances have opened exciting new avenues in our approach to studying factors that affect the global transcriptional landscape in bacteria. In this symposium we will focus on the interplay between acquisition of genetic material and changes in the global transcriptional profile in bacteria, and how seemingly stochastic processes such as chromosomal position or methylation patterns have a profound effect on the global transcriptional profile and bacterial phenotypes.

ORGANISERS

Lori Snyder, Mark Webber and Alan McNally

Chair : Mark Webber

Genetic disorders in bacteria

13:00 - 13:30

Genetic disorders in bacteria

Offered paper - Arginine is a critical substrate for the pathogenesis of P. aeruginosa in burn wound infections

13:30 - 13:45

Offered paper - Arginine is a critical substrate for the pathogenesis of P. aeruginosa in burn wound infections

Offered paper - Climbing Mount Improbable: Laboratory-based evolution of acid resistance in E. coli leads to a common transcriptional and phenotypic landscape via two distinct genomic routes

13:45 - 14:00

Offered paper - Climbing Mount Improbable: Laboratory-based evolution of acid resistance in E. coli leads to a common transcriptional and phenotypic landscape via two distinct genomic routes

Refreshments and exhibition

14:00 - 14:30

Refreshments and exhibition

Chair : Alan McNally

Transfer of noncoding DNA drives regulatory rewiring in bacteria

14:30 - 15:00

Transfer of noncoding DNA drives regulatory rewiring in bacteria

Using experimental evolution, genome resequencing and transcriptomics to understand mechanisms of co-evolution between P. aeruginosa and plasmids

15:00 - 15:30

Using experimental evolution, genome resequencing and transcriptomics to understand mechanisms of co-evolution between P. aeruginosa and plasmids

Unravelling regulation networks using mathematical modelling

15:30 - 16:00

Unravelling regulation networks using mathematical modelling

The hostile cell: Intrinsic antiviral immunity – part 2

The innate immune system represents the first line of defence against infection. It consists of a number of constitutively expressed and inducible factors that suppress or prevent virus infection. Some of these are well-characterised, others are still poorly understood. This symposium will highlight the roles of these anti-viral factors in the immune responses of both vertebrate and non-vertebrate species, and discuss the mechanisms by which they create an environment hostile to virus replication. Virus countermeasures to these processes will also be described. The symposium will take place concurrently with the restriction factor workshop, allowing a forum for the exchange of ideas between disparate groups of virologists.

ORGANISERS

Andrew MacDonald and James Stewart

HIV-1 restriction by SAMHD1

13:00 - 13:30

HIV-1 restriction by SAMHD1

Offered paper - The role of long-range chromatin reorganisation by Epstein-Barr virus in lymphoma development

13:30 - 13:45

Offered paper - The role of long-range chromatin reorganisation by Epstein-Barr virus in lymphoma development

Offered paper - Investigating the role of NS5A domain 3 in protecting hepatitis C virus proteins from degradation

13:45 - 14:00

Offered paper - Investigating the role of NS5A domain 3 in protecting hepatitis C virus proteins from degradation

The proteome under viral attack

14:00 - 14:30

The proteome under viral attack

Sunday 20 March, Afternoon

Pre-Conference networking workshop

18:00 - 20:00

Pre-Conference networking workshop

Monday 21 March, Morning

Open address & Hot Topic Lecture: Zika virus, from obscurity to threat

09:15 - 09:50

Open address & Hot Topic Lecture: Zika virus, from obscurity to threat

The Society and society: citizen science and antimicrobial resistance

10:00 - 10:30

The Society and society: citizen science and antimicrobial resistance

An evolutionary overview of transporters

10:00 - 10:30

An evolutionary overview of transporters

Zinc acquisition by human fungal pathogens

10:00 - 10:30

Zinc acquisition by human fungal pathogens

Acetyl phosphate-mediated protein acetylation

10:00 - 10:30

Acetyl phosphate-mediated protein acetylation

Welcome (SG, MIG) and dedication of the symposium to the memory of Richard Elliott

10:00 - 10:15

Welcome (SG, MIG) and dedication of the symposium to the memory of Richard Elliott

Ebola: response, sequencing, vaccines and survivors

10:15 - 10:45

Ebola: response, sequencing, vaccines and survivors

UK public investments addressing the AMR challenge

10:30 - 11:00

UK public investments addressing the AMR challenge

Primary active transporters

10:30 - 11:00

Primary active transporters

Cambialistic superoxide dismutases allow S. aureus to circumvent nutritional immunity

10:30 - 11:00

Cambialistic superoxide dismutases allow S. aureus to circumvent nutritional immunity

Acetylation-dependent signalling in bacterial chemotaxis

10:30 - 11:00

Acetylation-dependent signalling in bacterial chemotaxis

Loud and quiet – how human macrophages respond to Ebolavirus infection

10:45 - 11:15

Loud and quiet – how human macrophages respond to Ebolavirus infection

The economics causes of and solutions to AMR

11:00 - 11:30

The economics causes of and solutions to AMR

Secondary active transporters

11:00 - 11:30

Secondary active transporters

Offered paper - Human pathogenic fungi: adaptation to zinc nutritional immunity

11:00 - 11:15

Offered paper - Human pathogenic fungi: adaptation to zinc nutritional immunity

The role of post-translational modification in the PII signal transduction proteins

11:00 - 11:30

The role of post-translational modification in the PII signal transduction proteins

Offered paper - Exploiting nutritional immunity for antimicrobial drug discovery

11:15 - 11:30

Offered paper - Exploiting nutritional immunity for antimicrobial drug discovery

Refreshments and exhibition

11:15 - 11:45

Refreshments and exhibition

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Hantaviruses and their targets, and their targets' targets, and their targets' targets' targets

11:45 - 12:15

Hantaviruses and their targets, and their targets' targets, and their targets' targets' targets

The Small World Initiative: current and future vision

12:00 - 12:30

The Small World Initiative: current and future vision

Structure and mechanism of bacterial ABC transporters

12:00 - 12:30

Structure and mechanism of bacterial ABC transporters

Nutritional immunity: Metals at the host–pathogen interface

12:00 - 12:30

Nutritional immunity: Metals at the host–pathogen interface

Interplay between proteolysis and phosphorylation

12:00 - 12:30

Interplay between proteolysis and phosphorylation

Offered paper - Modelling the evolutionary trajectories of an expanding Morbillivirus genus

12:15 - 12:30

Offered paper - Modelling the evolutionary trajectories of an expanding Morbillivirus genus

International perspective on the Small World Initiative

12:30 - 13:00

International perspective on the Small World Initiative

Bacterial ECF transporters

12:30 - 13:00

Bacterial ECF transporters

Guts, germs and steel: Microbes and metal in the inflamed gut

12:30 - 13:00

Guts, germs and steel: Microbes and metal in the inflamed gut

Activation of pore-forming toxins

12:30 - 13:00

Activation of pore-forming toxins

Offered paper - Intra-patient Ebola virus genome variation correlates with outcome of infection

12:30 - 12:45

Offered paper - Intra-patient Ebola virus genome variation correlates with outcome of infection

Offered paper - Mutational analysis of conserved motifs of the Rift Valley fever virus nucleoprotein indicates novel functional residues

12:45 - 13:00

Offered paper - Mutational analysis of conserved motifs of the Rift Valley fever virus nucleoprotein indicates novel functional residues

Monday 21 March, Afternoon

Crowdsourcing new antibiotics: Novel Approaches Poster Exhibition

13:00 - 14:30

Crowdsourcing new antibiotics: Novel Approaches Poster Exhibition

Lunch, exhibition & poster viewing

13:00 - 14:30

Lunch, exhibition & poster viewing

Battling against nutritional immunity: Bacterial systems for avoiding zinc and copper stress

13:00 - 13:30

Battling against nutritional immunity: Bacterial systems for avoiding zinc and copper stress

Live at Lunch: Early Career Microbiologists' Forum launch event

13:30 - 14:15

Live at Lunch: Early Career Microbiologists' Forum launch event

Why is soil such a good hunting ground for antibiotics?

14:30 - 15:00

Why is soil such a good hunting ground for antibiotics?

Bacterial TRAP transporters

14:30 - 15:00

Bacterial TRAP transporters

Non-proteinaceous virulence factors of Francisella tularensis

14:30 - 15:00

Non-proteinaceous virulence factors of Francisella tularensis

Phosphorylation networks: Extensive communication between the sensor kinases controlling virulence in Pseudomonas aeruginosa

14:30 - 15:00

Phosphorylation networks: Extensive communication between the sensor kinases controlling virulence in Pseudomonas aeruginosa

Evolution in action: Climate change, biodiversity dynamics and emerging infectious disease

14:30 - 15:00

Evolution in action: Climate change, biodiversity dynamics and emerging infectious disease

Ebola virus innate immune evasion functions as antiviral targets

14:30 - 15:00

Ebola virus innate immune evasion functions as antiviral targets

Isolation and growth of uncultured microbes using iChips

15:00 - 15:30

Isolation and growth of uncultured microbes using iChips

Function and diversity in bacterial sugar transporters

15:00 - 15:30

Function and diversity in bacterial sugar transporters

Peptidoglycan synthesis in Chlamydia: Balancing immune evasion with requirements for cell division

15:00 - 15:30

Peptidoglycan synthesis in Chlamydia: Balancing immune evasion with requirements for cell division

Offered paper - ADP-ribosylating sirtuins in the microbial redox defence

15:00 - 15:15

Offered paper - ADP-ribosylating sirtuins in the microbial redox defence

Impact of environmental changes on ticks and tick-borne diseases

15:00 - 15:30

Impact of environmental changes on ticks and tick-borne diseases

Ebola virus entry and release: role of the viral glycoprotein

15:00 - 15:30

Ebola virus entry and release: role of the viral glycoprotein

Post-translational regulation of Type VI secretion in Serratia marcescens

15:15 - 15:45

Post-translational regulation of Type VI secretion in Serratia marcescens

Refreshments and exhibition

15:30 - 16:00

Refreshments and exhibition

Refreshments and exhibition

15:30 - 16:15

Refreshments and exhibition

Autophagy and intracellular bacteria

15:30 - 16:00

Autophagy and intracellular bacteria

Offered paper - Host inflammatory response to mosquito bites defined severity of mosquito-transmitted virus infection

15:30 - 15:45

Offered paper - Host inflammatory response to mosquito bites defined severity of mosquito-transmitted virus infection

Broadly-neutralising antibodies to dengue virus

15:30 - 16:00

Broadly-neutralising antibodies to dengue virus

Offered paper - Functional analysis of the Legionella pneumophila effector LtpM reveals a novel cytotoxic glycosyltransferase domain

15:45 - 16:00

Offered paper - Functional analysis of the Legionella pneumophila effector LtpM reveals a novel cytotoxic glycosyltransferase domain

Offered paper - Development of a rapid neutralisation assay for Bluetongue virus

15:45 - 16:00

Offered paper - Development of a rapid neutralisation assay for Bluetongue virus

Experiences implementing the Small World Initiative: an undergraduate perspective

16:00 - 16:30

Experiences implementing the Small World Initiative: an undergraduate perspective

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Offered paper - Structural and functional analyses of the outer membrane transport of aromatic hydrocarbons by the biodegrader Pseudomonas putida F1

16:15 - 16:30

Offered paper - Structural and functional analyses of the outer membrane transport of aromatic hydrocarbons by the biodegrader Pseudomonas putida F1

Experiences of implementing the Small World Initiative: A school partnership perspective

16:30 - 17:00

Experiences of implementing the Small World Initiative: A school partnership perspective

Offered paper - ABC-transporters and histidine kinases communicate to regulate antimicrobial peptide resistance in Gram-positive bacteria

16:30 - 16:45

Offered paper - ABC-transporters and histidine kinases communicate to regulate antimicrobial peptide resistance in Gram-positive bacteria

Using genome-wide studies to understand susceptibility to tuberculosis

16:30 - 17:00

Using genome-wide studies to understand susceptibility to tuberculosis

Pupylation-dependent and -independent proteasomal degradation in mycobacteria

16:30 - 17:00

Pupylation-dependent and -independent proteasomal degradation in mycobacteria

Binomics of temperate and tropical culicoides: Knowledge gaps and consequences for transmission of culicoides-borne viruses

16:30 - 17:00

Binomics of temperate and tropical culicoides: Knowledge gaps and consequences for transmission of culicoides-borne viruses

Host responses to Lassa fever

16:30 - 17:00

Host responses to Lassa fever

Offered paper - Structural basis for nutrient acquisition by dominant members of the human gut microbiota

16:45 - 17:00

Offered paper - Structural basis for nutrient acquisition by dominant members of the human gut microbiota

Using Citizen Science in the search for new antibiotics

17:00 - 17:30

Using Citizen Science in the search for new antibiotics

Structural basis of proton coupled transport in the PTR/POT family of membrane proteins

17:00 - 17:30

Structural basis of proton coupled transport in the PTR/POT family of membrane proteins

Molecular mechanisms of immune evasion: From complement to toxins

17:00 - 17:30

Molecular mechanisms of immune evasion: From complement to toxins

Offered paper - Biochemical characterisation of the Aedes aegypti SUMOylation pathway

17:00 - 17:15

Offered paper - Biochemical characterisation of the Aedes aegypti SUMOylation pathway

Future impact of climate change on infectious diseases of animals

17:00 - 17:30

Future impact of climate change on infectious diseases of animals

Flavivirus drug discovery

17:00 - 17:30

Flavivirus drug discovery

Functions of polyubiquitin chains in DNA damage bypass in budding yeast

17:15 - 17:45

Functions of polyubiquitin chains in DNA damage bypass in budding yeast

Networking

17:30 - 18:00

Networking

Efflux of metabolites in bacteria and its exploitation in biotechnology

17:30 - 18:00

Efflux of metabolites in bacteria and its exploitation in biotechnology

Host–parasite interactions under systemic conditions

17:30 - 18:00

Host–parasite interactions under systemic conditions

Viral haemorrhagic fevers other than Ebola virus

17:30 - 18:00

Viral haemorrhagic fevers other than Ebola virus

Peter Wildy Prize Lecture: Influenza – a world of discoveries, outbreaks and controversy

18:10 - 19:00

Peter Wildy Prize Lecture: Influenza – a world of discoveries, outbreaks and controversy

Crowdsourcing new antibiotics: Novel Approaches Poster Exhibition

19:00 - 21:00

Crowdsourcing new antibiotics: Novel Approaches Poster Exhibition

Poster viewing, drinks & exhibition

19:00 - 21:00

Poster viewing, drinks & exhibition

Meet the Speakers

19:30 - 20:30

Meet the Speakers

Society Band Night: The Radicles

20:15 - 22:00

Society Band Night: The Radicles

Tuesday 22 March, Morning

Microbiology Society Prize Medal Lecture: Decrypting microbe–host signals in the intestinal crypt: from homeostasis to pathology

09:00 - 09:50

Microbiology Society Prize Medal Lecture: Decrypting microbe–host signals in the intestinal crypt: from homeostasis to pathology

Identifying sugar transporters in filamentous fungi for engineering biofuel-producing yeast

10:00 - 10:30

Identifying sugar transporters in filamentous fungi for engineering biofuel-producing yeast

Now you see me, now you don't: Innate immune recognition of endoplasmic reticulum stress during infection with Brucella abortus

10:00 - 10:30

Now you see me, now you don't: Innate immune recognition of endoplasmic reticulum stress during infection with Brucella abortus

Exploiting yeast intra-species diversity to unravel complex phenotypes

10:00 - 10:30

Exploiting yeast intra-species diversity to unravel complex phenotypes

Tuberculosis and One Health: comparative analysis of human and bovine tubercle bacilli

10:00 - 10:30

Tuberculosis and One Health: comparative analysis of human and bovine tubercle bacilli

Protein O-glycosylation in Actinobacteria: What's it for?

10:00 - 10:30

Protein O-glycosylation in Actinobacteria: What's it for?

Protection from the "Red Queen": Co-evolution and conflict among hosts, parasites, and defensive microbes

10:00 - 10:30

Protection from the "Red Queen": Co-evolution and conflict among hosts, parasites, and defensive microbes

The role of PYHIN proteins in innate immunity

10:00 - 10:30

The role of PYHIN proteins in innate immunity

Hijacked then lost in translation: The plight of the recombinant host cell in membrane protein structural biology projects

10:30 - 11:00

Hijacked then lost in translation: The plight of the recombinant host cell in membrane protein structural biology projects

Manipulation of the immune system through engagement of lectin receptors by bacterial pathogens

10:30 - 11:00

Manipulation of the immune system through engagement of lectin receptors by bacterial pathogens

Kluyveromyces marxianus – an emerging yeast for cell factory applications

10:30 - 11:00

Kluyveromyces marxianus – an emerging yeast for cell factory applications

Leprosy – zoonosis and anthroponosis

10:30 - 11:00

Leprosy – zoonosis and anthroponosis

Characterising protein glycosylation in microbial pathogens

10:30 - 11:00

Characterising protein glycosylation in microbial pathogens

Co-evolution of mycobacteria with their hosts

10:30 - 11:00

Co-evolution of mycobacteria with their hosts

Using genetic approaches to identify factors involved in cell-intrinsic immunity

10:30 - 11:00

Using genetic approaches to identify factors involved in cell-intrinsic immunity

Offered paper - Engineering the bacterial flagellum: conversion into a high efficiency protein secretion machine

11:00 - 11:15

Offered paper - Engineering the bacterial flagellum: conversion into a high efficiency protein secretion machine

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

Mycobacterium avium, subspecies paratuberculosis and Johne’s disease

11:00 - 11:30

Mycobacterium avium, subspecies paratuberculosis and Johne’s disease

Know your enemy: Fungal cell wall glycans that drive immune recognition mechanisms

11:00 - 11:30

Know your enemy: Fungal cell wall glycans that drive immune recognition mechanisms

Offered paper - Genotypic and phenotypic diversity arising during the clonal expansion of the current MDR monophasic Salmonella typhimurium epidemic in the UK

11:00 - 11:15

Offered paper - Genotypic and phenotypic diversity arising during the clonal expansion of the current MDR monophasic Salmonella typhimurium epidemic in the UK

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

Offered paper - Exploring the potential TRAP and ABC solute uptake transporters from the phototroph Rhodopseudomonas palustris for use in biotechnology

11:15 - 11:30

Offered paper - Exploring the potential TRAP and ABC solute uptake transporters from the phototroph Rhodopseudomonas palustris for use in biotechnology

Offered paper - Public goods cooperation in P. aeruginosa

11:15 - 11:30

Offered paper - Public goods cooperation in P. aeruginosa

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

"Class"-ified information: Type four pili and meningoccocal immune evasion

11:30 - 12:00

"Class"-ified information: Type four pili and meningoccocal immune evasion

Offered paper - Mining marine cellular communication networks for translational societal benefit

11:30 - 11:45

Offered paper - Mining marine cellular communication networks for translational societal benefit

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Antiviral function of Mx proteins

11:30 - 12:00

Antiviral function of Mx proteins

Offered paper - The bacteriocin arsenal of Pseudomonas

11:45 - 12:00

Offered paper - The bacteriocin arsenal of Pseudomonas

An example from industry

12:00 - 13:00

An example from industry

Microbial evasion or immune tolerance? Pneumococcal interactions with host immunity during carriage and disease

12:00 - 12:30

Microbial evasion or immune tolerance? Pneumococcal interactions with host immunity during carriage and disease

Zygosaccharomyces bailii: Reorientating a spoilage yeast for biotechnology

12:00 - 12:30

Zygosaccharomyces bailii: Reorientating a spoilage yeast for biotechnology

Daring to be different – heterogeneity among identical twins

12:00 - 12:30

Daring to be different – heterogeneity among identical twins

Phosphoarginine serves as a degradation tag of the ClpC:ClpP protease

12:00 - 12:30

Phosphoarginine serves as a degradation tag of the ClpC:ClpP protease

Polychromatic 'greenbeard' genes protect against defection strategies in a social amoeba

12:00 - 12:30

Polychromatic 'greenbeard' genes protect against defection strategies in a social amoeba

Offered paper - Bacterial flagellin opens the door for virus entry

12:00 - 12:15

Offered paper - Bacterial flagellin opens the door for virus entry

Offered paper - Species difference in ANP32A underlies influenza A virus polymerase host restriction

12:15 - 12:30

Offered paper - Species difference in ANP32A underlies influenza A virus polymerase host restriction

Legionella modulators of membrane dynamics and cell migration

12:30 - 13:00

Legionella modulators of membrane dynamics and cell migration

Production of recombinant proteins and high-value chemicals in Chlamydomonas reinhardtii

12:30 - 13:00

Production of recombinant proteins and high-value chemicals in Chlamydomonas reinhardtii

Offered paper - The Buruli ulcer exotoxin, mycolactone, inhibits Sec61-dependent translocation of secreted proteins

12:30 - 12:45

Offered paper - The Buruli ulcer exotoxin, mycolactone, inhibits Sec61-dependent translocation of secreted proteins

A second line of defence: Exploring the functionality and hidden roles of gliotoxin bisthiomethylation in Aspergillus fumigateus

12:30 - 13:00

A second line of defence: Exploring the functionality and hidden roles of gliotoxin bisthiomethylation in Aspergillus fumigateus

Genome evolution in the Chlamydiae – ubiquitous intracellular symbionts and pathogens

12:30 - 13:00

Genome evolution in the Chlamydiae – ubiquitous intracellular symbionts and pathogens

Induction and suppression of the interferon response by RNA viruses

12:30 - 13:00

Induction and suppression of the interferon response by RNA viruses

Offered paper - Interactions between M. avium with avian and human macrophage

12:45 - 13:00

Offered paper - Interactions between M. avium with avian and human macrophage

Tuesday 22 March, Afternoon

Lunch, exhibition & poster viewing

13:00 - 14:30

Lunch, exhibition & poster viewing

Cyanobacterial resistance to phage infection: Implications for genome evolution and host–phage coexistence

13:00 - 13:30

Cyanobacterial resistance to phage infection: Implications for genome evolution and host–phage coexistence

Live at Lunch: Big Data or Bust

13:15 - 14:15

Live at Lunch: Big Data or Bust

Live at Lunch: An Audience with... Professor Philippe Sansonetti

13:30 - 14:15

Live at Lunch: An Audience with... Professor Philippe Sansonetti

Update on avian influenza and MERS-CoV

14:00 - 14:30

Update on avian influenza and MERS-CoV

The application of rapid molecular respiratory point of care tests in relation to clinical and infection control paediatric practice

14:30 - 15:00

The application of rapid molecular respiratory point of care tests in relation to clinical and infection control paediatric practice

Understanding Campylobacter jejuni-mediated diseases pathogenesis: an update and future challenges

14:30 - 15:00

Understanding Campylobacter jejuni-mediated diseases pathogenesis: an update and future challenges

Brewing up biodiversity for biotechnology – flavour variation in British ale yeasts

14:30 - 15:00

Brewing up biodiversity for biotechnology – flavour variation in British ale yeasts

Challenges and progress in human TB vaccine development

14:30 - 15:00

Challenges and progress in human TB vaccine development

Proteostasis – balancing the protein economy in Saccharomyces

14:30 - 15:00

Proteostasis – balancing the protein economy in Saccharomyces

Carefree Coccidia? Evolution of a hit and run parasite…

14:30 - 15:00

Carefree Coccidia? Evolution of a hit and run parasite…

Virology meets proteomics: Understanding cellular defense mechanisms against herpesvirus infections

14:30 - 15:00

Virology meets proteomics: Understanding cellular defense mechanisms against herpesvirus infections

Commercial company presentations

15:00 - 15:30

Commercial company presentations

Role of cell death signalling pathways in antibacterial immune defense

15:00 - 15:30

Role of cell death signalling pathways in antibacterial immune defense

Ecological role of yeast flavours

15:00 - 15:30

Ecological role of yeast flavours

Offered paper - Hypoxic signalling modulates neutrophil nitric oxide in a zebrafish–Mycobacteria model

15:00 - 15:15

Offered paper - Hypoxic signalling modulates neutrophil nitric oxide in a zebrafish–Mycobacteria model

Offered paper - Understanding the role of acetyl-lysine post-translational modifications in Campylobacter jejuni

15:00 - 15:15

Offered paper - Understanding the role of acetyl-lysine post-translational modifications in Campylobacter jejuni

The molecular architecture of a parasite cell surface

15:00 - 15:30

The molecular architecture of a parasite cell surface

Offered paper - Regulation of HSV-1 infection by the non-homologous end joining machinery

15:00 - 15:15

Offered paper - Regulation of HSV-1 infection by the non-homologous end joining machinery

Offered paper - Peptidoglycan recycling in Mycobacteria

15:15 - 15:30

Offered paper - Peptidoglycan recycling in Mycobacteria

The redoxome: from oxidative thiol modification to N-chlorination

15:15 - 15:45

The redoxome: from oxidative thiol modification to N-chlorination

Offered paper - Atypical macropinocytosis of Measles virus particles in lymphocytes

15:15 - 15:30

Offered paper - Atypical macropinocytosis of Measles virus particles in lymphocytes

Refreshments and exhibition

15:30 - 15:45

Refreshments and exhibition

Using Citrobacter rodentium to model enteric bacterial infections and host responses

15:30 - 16:00

Using Citrobacter rodentium to model enteric bacterial infections and host responses

Offered paper - Genetic dissection of lactose assimilation in Kluyveromyces marxianus

15:30 - 15:45

Offered paper - Genetic dissection of lactose assimilation in Kluyveromyces marxianus

Lysosomal storage disorders cause susceptibility to tuberculosis by compromising macrophage migration

15:30 - 16:00

Lysosomal storage disorders cause susceptibility to tuberculosis by compromising macrophage migration

AID and gene conversions on both sides of the host–parasite arms race

15:30 - 16:00

AID and gene conversions on both sides of the host–parasite arms race

Tethering virions – an ancient strategy to prevent viral spread

15:30 - 16:00

Tethering virions – an ancient strategy to prevent viral spread

Monitoring and treating hepatitis B carriers now and in the future

15:45 - 16:15

Monitoring and treating hepatitis B carriers now and in the future

Offered paper - New yeast hybrids: Generation and analysis

15:45 - 16:00

Offered paper - New yeast hybrids: Generation and analysis

Refreshments and exhibition

15:45 - 16:30

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Chair's report, Treasurer's report, research report, training and website update

16:15 - 17:00

Chair's report, Treasurer's report, research report, training and website update

Intracellular survival strategy of Burkholderia cepacia complex isolates

16:30 - 17:00

Intracellular survival strategy of Burkholderia cepacia complex isolates

Beneficial aspects of S. uvarum, S. kudriavzevii and Saccharomyces hybrids in the aroma synthesis during alcoholic fermentation

16:30 - 17:00

Beneficial aspects of S. uvarum, S. kudriavzevii and Saccharomyces hybrids in the aroma synthesis during alcoholic fermentation

The evolution of MTBC and the novel STB

16:30 - 17:00

The evolution of MTBC and the novel STB

Glyco- and quantitative-proteomics in Trypanosoma brucei

16:30 - 17:00

Glyco- and quantitative-proteomics in Trypanosoma brucei

Malaria genomics: a constantly evolving population of parasites

16:30 - 17:00

Malaria genomics: a constantly evolving population of parasites

Offered paper - Direct cell-to-cell spread favoured by wild-type HCMV confers resistance to intrinsic, innate and adaptive immune defences

16:30 - 16:45

Offered paper - Direct cell-to-cell spread favoured by wild-type HCMV confers resistance to intrinsic, innate and adaptive immune defences

Offered paper - Applying advances in light microscopy to the high-resolution tracking of chikungunya virus (CHIKV) non-structural protein 3 (nsP3) in human cells

16:45 - 17:00

Offered paper - Applying advances in light microscopy to the high-resolution tracking of chikungunya virus (CHIKV) non-structural protein 3 (nsP3) in human cells

Offered paper - Targeting of the host sphingosine-1-phosphate (S1P) axis by intracellular bacterial pathogens: Characterization of bacterial-encoded S1P lyases required for virulence and intracellular survival

17:00 - 17:15

Offered paper - Targeting of the host sphingosine-1-phosphate (S1P) axis by intracellular bacterial pathogens: Characterization of bacterial-encoded S1P lyases required for virulence and intracellular survival

Lactic acid bacteria in cheese for heart health

17:00 - 17:30

Lactic acid bacteria in cheese for heart health

Using whole genome sequencing to uncover the biology of NTM infection

17:00 - 17:30

Using whole genome sequencing to uncover the biology of NTM infection

Offered paper - The Streptomyces coelicolor glycoproteome includes enzymes involved in cell wall biogenesis

17:00 - 17:15

Offered paper - The Streptomyces coelicolor glycoproteome includes enzymes involved in cell wall biogenesis

Discovery of novel CRISPR-Cas systems by mining genomic and metagenomic databases

17:00 - 17:30

Discovery of novel CRISPR-Cas systems by mining genomic and metagenomic databases

Defense and counter-defense in antiviral RNA silencing pathways of insects

17:00 - 17:30

Defense and counter-defense in antiviral RNA silencing pathways of insects

Offered paper - Staphylococcal enterotoxin-like toxin X (SEIX) binds to neutrophils in a sialic acid dependent manner and inhibits neutrophil function

17:15 - 17:30

Offered paper - Staphylococcal enterotoxin-like toxin X (SEIX) binds to neutrophils in a sialic acid dependent manner and inhibits neutrophil function

Quantitative proteomics at a global scale – methods and applications in bacteria

17:15 - 17:45

Quantitative proteomics at a global scale – methods and applications in bacteria

Yersinia toxin injection

17:30 - 18:00

Yersinia toxin injection

Harnessing raw milk microbes to make cheeses of place: A new frontier for farmhouse cheese

17:30 - 18:00

Harnessing raw milk microbes to make cheeses of place: A new frontier for farmhouse cheese

Pain control by Mycobacterium ulcerans secreted mycolactone

17:30 - 18:00

Pain control by Mycobacterium ulcerans secreted mycolactone

Offered paper - The structure of phage–bacteria networks from a long-term co-evolution study of arms race and fluctuating selection dynamics

17:30 - 17:45

Offered paper - The structure of phage–bacteria networks from a long-term co-evolution study of arms race and fluctuating selection dynamics

Offered paper - MxA-transgenic mice cannot efficiently control influenza A viruses carrying nucleoproteins with human signature

17:30 - 17:45

Offered paper - MxA-transgenic mice cannot efficiently control influenza A viruses carrying nucleoproteins with human signature

Fleming Prize Lecture: The unexpected complexity of bacterial genomes

18:10 - 19:00

Fleming Prize Lecture: The unexpected complexity of bacterial genomes

Poster viewing, drinks & exhibition

19:00 - 21:00

Poster viewing, drinks & exhibition

Live Debate: Human Face of Ebola and Ebola Trials

19:15 - 20:15

Live Debate: Human Face of Ebola and Ebola Trials

Wednesday 23 March, Morning

Marjory Stephenson Prize Lecture: Petri plates to Petri nets: the path to systems microbiology

09:00 - 09:50

Marjory Stephenson Prize Lecture: Petri plates to Petri nets: the path to systems microbiology

Listeria monocytogenes: a unique model in infection biology

10:00 - 10:30

Listeria monocytogenes: a unique model in infection biology

Surviving protein quality control failures: From yeast to mammals

10:00 - 10:30

Surviving protein quality control failures: From yeast to mammals

Offered paper - The role of pseudotypes in influenza pandemic preparedness: an undergraduate-led serology and social media exercise

10:00 - 10:12

Offered paper - The role of pseudotypes in influenza pandemic preparedness: an undergraduate-led serology and social media exercise

Finding a new niche: mining for antibiotics in the nest of leafcutter ants

10:00 - 10:30

Finding a new niche: mining for antibiotics in the nest of leafcutter ants

From gene to pathway to genome engineering

10:00 - 10:30

From gene to pathway to genome engineering

Offered paper - A systematic screen of the entire human cytomegalovirus genome for novel NK cell immunomodulators

10:00 - 10:12

Offered paper - A systematic screen of the entire human cytomegalovirus genome for novel NK cell immunomodulators

Offered paper - Identification of novel cis- and trans-activities of FMDV 3Dpol necessary for the formation of viral RNA replication complexes

10:00 - 10:12

Offered paper - Identification of novel cis- and trans-activities of FMDV 3Dpol necessary for the formation of viral RNA replication complexes

Offered paper - Examining the interplay between the human innate immune system and the non-structural protein (NSs) of emerging tick-borne phleboviruses

10:00 - 10:12

Offered paper - Examining the interplay between the human innate immune system and the non-structural protein (NSs) of emerging tick-borne phleboviruses

Offered paper - Use of an Ebola transcription- and replication-competent virus-like particle (trVLP) system to screen for antiviral interferon-stimulated genes

10:00 - 10:12

Offered paper - Use of an Ebola transcription- and replication-competent virus-like particle (trVLP) system to screen for antiviral interferon-stimulated genes

Offered paper - Generation of a genetically stable and antigenically matched H3N2 3C.2a live-attenuated influenza virus vaccine candidate

10:12 - 10:24

Offered paper - Generation of a genetically stable and antigenically matched H3N2 3C.2a live-attenuated influenza virus vaccine candidate

Offered paper - Mechanisms of immune modulation by vaccinia virus protein C16

10:12 - 10:24

Offered paper - Mechanisms of immune modulation by vaccinia virus protein C16

Offered paper - IBV accessory protein 3a, dsRNA and innate immune evasion

10:12 - 10:24

Offered paper - IBV accessory protein 3a, dsRNA and innate immune evasion

Offered paper - TRIM22 restricts influenza A virus as part of an intrinsic antiviral defence

10:12 - 10:24

Offered paper - TRIM22 restricts influenza A virus as part of an intrinsic antiviral defence

Offered paper - Production of lentiviral particles containing Ebola virus RNA as reference materials for nucleic acid technology-based assays

10:12 - 10:24

Offered paper - Production of lentiviral particles containing Ebola virus RNA as reference materials for nucleic acid technology-based assays

Offered paper - The role of protease in studies making use of viral pseudotype particles

10:24 - 10:36

Offered paper - The role of protease in studies making use of viral pseudotype particles

Offered paper - Characterisation of epitope-specific humoral responses to human cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in solid organ transplant recipient candidates

10:24 - 10:36

Offered paper - Characterisation of epitope-specific humoral responses to human cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in solid organ transplant recipient candidates

Offered paper - HCV genotype 3 modulation of host cell metabolism pathways and implication in disease progression

10:24 - 10:36

Offered paper - HCV genotype 3 modulation of host cell metabolism pathways and implication in disease progression

Offered paper - The interferon-stimulated gene Ly6E restricts influenza A replication

10:24 - 10:36

Offered paper - The interferon-stimulated gene Ly6E restricts influenza A replication

Offered paper - Reference materials for Ebolavirus diagnosis and immune respone analysis

10:24 - 10:36

Offered paper - Reference materials for Ebolavirus diagnosis and immune respone analysis

Offered paper - Differential expression of a phase variable type I restriction modification system impacts the virulence of Streptococcus pneumoniae

10:30 - 10:45

Offered paper - Differential expression of a phase variable type I restriction modification system impacts the virulence of Streptococcus pneumoniae

Deciphering the roles regulatory RNAs play in the lifestyles of Bacillus subtilis

10:30 - 11:00

Deciphering the roles regulatory RNAs play in the lifestyles of Bacillus subtilis

Offered paper - Microbial life and the death of glaciers: How does microbial ecosystem engineering accelerate glacier melting?

10:30 - 10:45

Offered paper - Microbial life and the death of glaciers: How does microbial ecosystem engineering accelerate glacier melting?

Innovative routes to monoterpene hydrocarbons and their derivatives

10:30 - 11:00

Innovative routes to monoterpene hydrocarbons and their derivatives

Offered paper - Parainfluenza virus: Genetic diversity, virulence and antiviral susceptibility

10:36 - 10:48

Offered paper - Parainfluenza virus: Genetic diversity, virulence and antiviral susceptibility

Offered paper - Identification of five NK cell evasion funcations in a single HCMV gene family

10:36 - 10:48

Offered paper - Identification of five NK cell evasion funcations in a single HCMV gene family

Offered paper - The influence of sequence and RNA structure on recombination in Enteroviruses

10:36 - 10:48

Offered paper - The influence of sequence and RNA structure on recombination in Enteroviruses

Offered paper - IFITM3 restricts virus-induced pathogenesis by regulating myeloid cell production of interleukin-6

10:36 - 10:48

Offered paper - IFITM3 restricts virus-induced pathogenesis by regulating myeloid cell production of interleukin-6

Offered paper - The nucleoprotein of Ebola-Makona interacts with HSP70 to promote protein stability

10:36 - 10:48

Offered paper - The nucleoprotein of Ebola-Makona interacts with HSP70 to promote protein stability

Offered paper - Polymeric artificial cellular environments interfere with the expression of virulence factors in Vibrio chloerae compromising its pathogenesis

10:45 - 11:00

Offered paper - Polymeric artificial cellular environments interfere with the expression of virulence factors in Vibrio chloerae compromising its pathogenesis

Offered paper - Multiple drug resistance identified from a soil microbiome using functional metagenomics

10:45 - 11:00

Offered paper - Multiple drug resistance identified from a soil microbiome using functional metagenomics

Offered paper - Increased detection of Seoul hantavirus in the United Kingdom

10:48 - 11:00

Offered paper - Increased detection of Seoul hantavirus in the United Kingdom

Offered paper - Characterisation of a non-lytic release mechanism of BK polyomavirus from infected cells

10:48 - 11:00

Offered paper - Characterisation of a non-lytic release mechanism of BK polyomavirus from infected cells

Offered paper - Infectious bronchitis virus and the AKT signalling pathway

10:48 - 11:00

Offered paper - Infectious bronchitis virus and the AKT signalling pathway

Offered paper - Avian IFITMs: restricting avian viral infection

10:48 - 11:00

Offered paper - Avian IFITMs: restricting avian viral infection

Refreshments and exhibition

10:48 - 11:18

Refreshments and exhibition

Offered paper - Periodontal pathogen sialidases at the oral host–pathogen interface

11:00 - 11:15

Offered paper - Periodontal pathogen sialidases at the oral host–pathogen interface

Genome regulation and cellular ageing in fission yeast

11:00 - 11:30

Genome regulation and cellular ageing in fission yeast

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

Offered paper - Adaptation to environmental change comes with a cost of reduced bacterial community ecosystem functioning

11:00 - 11:15

Offered paper - Adaptation to environmental change comes with a cost of reduced bacterial community ecosystem functioning

Refreshments and exhibition

11:00 - 11:30

Refreshments and exhibition

Offered paper - Sequencing human cytomegalovirus genomes directly from clinical material

11:00 - 11:12

Offered paper - Sequencing human cytomegalovirus genomes directly from clinical material

Offered paper - Phylogenetic analysis and evolutionary history of louping ill virus, a neglected pathogen of sheep & grouse in Britain

11:00 - 11:12

Offered paper - Phylogenetic analysis and evolutionary history of louping ill virus, a neglected pathogen of sheep & grouse in Britain

Offered paper - Neutralising potency of the innate pattern recognition receptors L-ficolin and H-ficolin against hepatitis C virus and Ebola virus infection

11:00 - 11:12

Offered paper - Neutralising potency of the innate pattern recognition receptors L-ficolin and H-ficolin against hepatitis C virus and Ebola virus infection

Offered paper

11:12 - 11:24

Offered paper

Offered paper - Mutational analysis and evolutionary history of louping ill virus, a neglected pathogen of sheep and grouse in Britain

11:12 - 11:24

Offered paper - Mutational analysis and evolutionary history of louping ill virus, a neglected pathogen of sheep and grouse in Britain

Offered paper - Characterising retroviral restriction by TRIM proteins

11:12 - 11:24

Offered paper - Characterising retroviral restriction by TRIM proteins

Offered paper - LPS accelerates uptake of bacterial outer membrane vesicles into host cells

11:15 - 11:30

Offered paper - LPS accelerates uptake of bacterial outer membrane vesicles into host cells

Offered paper - Benthic nitrate reduction is mediated by NAP nitrate reductase along the salinity gradient of an estuarine and coastal bay ecosystem

11:15 - 11:30

Offered paper - Benthic nitrate reduction is mediated by NAP nitrate reductase along the salinity gradient of an estuarine and coastal bay ecosystem

Offered paper - Elucidating cellular expression changes induced by infection with the Ebola virus Makona strain

11:18 - 11:30

Offered paper - Elucidating cellular expression changes induced by infection with the Ebola virus Makona strain

Offered paper - Hepatitis B: a DNA virus that assembles using a mechanism from an RNA virus

11:24 - 11:36

Offered paper - Hepatitis B: a DNA virus that assembles using a mechanism from an RNA virus

Refreshments and exhibition

11:24 - 11:54

Refreshments and exhibition

Refreshments and exhibition

11:24 - 11:54

Refreshments and exhibition

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Offered paper - Isolation of patients with influenza: experience of Newcastle upon Tyne Hospitals NHS Foundation Trust 2014/2015

11:30 - 11:42

Offered paper - Isolation of patients with influenza: experience of Newcastle upon Tyne Hospitals NHS Foundation Trust 2014/2015

Refreshments and exhibition

11:30 - 12:00

Refreshments and exhibition

Offered paper - Florine and norine: powerful tools for in silico genome mining leading to discovery of novel nonribosomal peptides

11:30 - 11:45

Offered paper - Florine and norine: powerful tools for in silico genome mining leading to discovery of novel nonribosomal peptides

Offered paper - Tracking naturally acquired immunity to Ebola virus Ziare (EBOV) infection in survivors of the 2014–15 West Africa outbreak

11:30 - 11:42

Offered paper - Tracking naturally acquired immunity to Ebola virus Ziare (EBOV) infection in survivors of the 2014–15 West Africa outbreak

Refreshments and exhibition

11:36 - 12:06

Refreshments and exhibition

Offered paper - Genotypic and phenotypic determination of drug resistance in herpes simplex virus type 1 and 2 infections in the UK

11:42 - 11:54

Offered paper - Genotypic and phenotypic determination of drug resistance in herpes simplex virus type 1 and 2 infections in the UK

Offered paper - Lujo virus and LCMV nucleoproteins enhance translation of viral-like mRNA through translation factor recruitment suggesting a novel method for mRNA circularisation

11:42 - 11:54

Offered paper - Lujo virus and LCMV nucleoproteins enhance translation of viral-like mRNA through translation factor recruitment suggesting a novel method for mRNA circularisation

Offered paper - Discovering novel lantibiotics through bacterial genome mining and proteomics

11:45 - 12:00

Offered paper - Discovering novel lantibiotics through bacterial genome mining and proteomics

Offered paper - A prospective study of Epstein-Barr virus and host immune response gene expression in sequential blood samples collected from bone marrow transplant recipients

11:54 - 12:06

Offered paper - A prospective study of Epstein-Barr virus and host immune response gene expression in sequential blood samples collected from bone marrow transplant recipients

Offered paper - Next generation sequencing reveals new Southern African Territories genotypes bringing us closer to understanding the history of foot-and-mouth disease virus in Africa

11:54 - 12:06

Offered paper - Next generation sequencing reveals new Southern African Territories genotypes bringing us closer to understanding the history of foot-and-mouth disease virus in Africa

Offered paper - Functional characterisation of TMEM156; one of the most highly induced interferon stimulated genes in primary porcine cells

11:54 - 12:06

Offered paper - Functional characterisation of TMEM156; one of the most highly induced interferon stimulated genes in primary porcine cells

Offered paper - Stalling to a halt – transcriptome analysis of Puumala virus infected cells

11:54 - 12:06

Offered paper - Stalling to a halt – transcriptome analysis of Puumala virus infected cells

Offered paper - Use of genomics to analyse the geographical and historical diversity of a Pseudomonas aeruginosa transmissible strain

12:00 - 12:15

Offered paper - Use of genomics to analyse the geographical and historical diversity of a Pseudomonas aeruginosa transmissible strain

Insights into the origin of virulence from model organisms

12:00 - 12:30

Insights into the origin of virulence from model organisms

Offered paper - Factors governing in planta growth of Escherichia coli O157:H7

12:00 - 12:15

Offered paper - Factors governing in planta growth of Escherichia coli O157:H7

Engineering yeast: Synthetic modularity at the gene, circuit, pathway and genome level

12:00 - 12:30

Engineering yeast: Synthetic modularity at the gene, circuit, pathway and genome level

Offered paper - Neonatal HSV disease in the UK and RoI: burden of disease and role of risk factors

12:06 - 12:18

Offered paper - Neonatal HSV disease in the UK and RoI: burden of disease and role of risk factors

Offered paper - Herpes simplex virus-1 proteins UL7 and UL51: cellular localisation and role during virion assembly

12:06 - 12:18

Offered paper - Herpes simplex virus-1 proteins UL7 and UL51: cellular localisation and role during virion assembly

Offered paper - Stabilising attenuating mutations in poliovaccines against loss through recombination

12:06 - 12:18

Offered paper - Stabilising attenuating mutations in poliovaccines against loss through recombination

Offered paper - Interplay between hepatitis C virus and the circadian clock

12:06 - 12:18

Offered paper - Interplay between hepatitis C virus and the circadian clock

Offered paper - Exploiting the reverse genetics system for severe fever with thrombocytopenia syndrome virus to study Phlebovirus tropism

12:06 - 12:18

Offered paper - Exploiting the reverse genetics system for severe fever with thrombocytopenia syndrome virus to study Phlebovirus tropism

Offered paper - A microbiota approach to an interdigital skin infection

12:15 - 12:30

Offered paper - A microbiota approach to an interdigital skin infection

Offered paper - Isosaccharininc acids from anaerobic, alkaline cellulose degradation products as an organic carbon source within the disposal concept for intermediate level radioactive wastes

12:15 - 12:30

Offered paper - Isosaccharininc acids from anaerobic, alkaline cellulose degradation products as an organic carbon source within the disposal concept for intermediate level radioactive wastes

Offered paper - Establishing a framework for pre-emptive drug resistance genotyping: next generation sequencing following primary HCMV infection after high-risk, seromismatched transplantation

12:18 - 12:30

Offered paper - Establishing a framework for pre-emptive drug resistance genotyping: next generation sequencing following primary HCMV infection after high-risk, seromismatched transplantation

Offered paper - Systematic mapping of poxvirus subviral structure using quantitative proteomics and super-resolution microscopy

12:18 - 12:30

Offered paper - Systematic mapping of poxvirus subviral structure using quantitative proteomics and super-resolution microscopy

Offered paper - Is that a sphingosine in your pocket or are you just happy to see me? The role of the pocket factor in Enterovirus uncoating and capsid stability

12:18 - 12:30

Offered paper - Is that a sphingosine in your pocket or are you just happy to see me? The role of the pocket factor in Enterovirus uncoating and capsid stability

Offered paper - Viral targeting reveals the positive role of ubiquitin specific peptidase 7 (USP7) in the interferon response

12:18 - 12:30

Offered paper - Viral targeting reveals the positive role of ubiquitin specific peptidase 7 (USP7) in the interferon response

Offered paper - Use of Ebola pseudoparticles to interrogate the impact of Ebola virus glycoprotein evolution during the West African outbreak

12:18 - 12:30

Offered paper - Use of Ebola pseudoparticles to interrogate the impact of Ebola virus glycoprotein evolution during the West African outbreak

Offered paper - Inhibition of Helicobacter pylori by sulfonamides

12:30 - 12:45

Offered paper - Inhibition of Helicobacter pylori by sulfonamides

Infecting amoebae with mycobacteria to study conserved mechanisms of innate immunity

12:30 - 13:00

Infecting amoebae with mycobacteria to study conserved mechanisms of innate immunity

Offered paper - Whole genome sequencing of HIV-1 – a multifunctional tool

12:30 - 12:42

Offered paper - Whole genome sequencing of HIV-1 – a multifunctional tool

Offered paper - Syntrophic paraffin biodegradation under methanogenic conditions

12:30 - 12:45

Offered paper - Syntrophic paraffin biodegradation under methanogenic conditions

Diversification of natural and non-natural products using engineered biosynthetic pathways and enzymes

12:30 - 13:00

Diversification of natural and non-natural products using engineered biosynthetic pathways and enzymes

Offered paper - The role of retrograde transport in vaccinia virus replication

12:30 - 12:42

Offered paper - The role of retrograde transport in vaccinia virus replication

Offered paper - Follicular dendritic cell: a key player in the pathogenesis of foot-and-mouth disease virus

12:30 - 12:42

Offered paper - Follicular dendritic cell: a key player in the pathogenesis of foot-and-mouth disease virus

Offered paper - Inhibition of retroviral infection by SAMHD1 through dNTP degradation requires stable tetramer formation

12:30 - 12:42

Offered paper - Inhibition of retroviral infection by SAMHD1 through dNTP degradation requires stable tetramer formation

Offered paper - Differential gene expression analysis of acute Ebola virus patients with fatal or non-fatal infections

12:30 - 12:42

Offered paper - Differential gene expression analysis of acute Ebola virus patients with fatal or non-fatal infections

Offered paper - Norovirus evolution: understanding and characterising the emergence of novel strains in the population

12:42 - 12:54

Offered paper - Norovirus evolution: understanding and characterising the emergence of novel strains in the population

Offered paper - Understanding the mechanisms of HSV-1 egress and release from cells

12:42 - 12:54

Offered paper - Understanding the mechanisms of HSV-1 egress and release from cells

Offered paper - Investigating the hepatitis C virus replication complex using super-resolution microscopy

12:42 - 12:54

Offered paper - Investigating the hepatitis C virus replication complex using super-resolution microscopy

Offered paper - Innate immunity to arboviruses at cutaneous inoculation sites

12:42 - 12:54

Offered paper - Innate immunity to arboviruses at cutaneous inoculation sites

Offered paper - Production of an antigen reference material for Ebola virus diagnostics

12:42 - 12:54

Offered paper - Production of an antigen reference material for Ebola virus diagnostics

Offered paper - The impact of the microbiota on Clostridium difficile colonisation and disease severity

12:45 - 13:00

Offered paper - The impact of the microbiota on Clostridium difficile colonisation and disease severity

Offered paper - IMNGS: A comprehensive open resource of processed 16S rRNA microbial profiles for ecology and diversity studies

12:45 - 13:00

Offered paper - IMNGS: A comprehensive open resource of processed 16S rRNA microbial profiles for ecology and diversity studies

Offered paper - HSV1 lacking VP22 replicates and spreads in primary human fibroblasts without producing cytopathic effect

12:54 - 13:00

Offered paper - HSV1 lacking VP22 replicates and spreads in primary human fibroblasts without producing cytopathic effect

Wednesday 23 March, Afternoon

Offered paper - HSV1 lacking VP22 replicates and spreads in primary human fibroblasts without producing cytopathic effect

13:00 - 13:06

Offered paper - HSV1 lacking VP22 replicates and spreads in primary human fibroblasts without producing cytopathic effect

iGEM poster exhibition

13:00 - 14:30

iGEM poster exhibition

Live at Lunch: International Committee on Taxonomy of Viruses

13:00 - 14:30

Live at Lunch: International Committee on Taxonomy of Viruses

Lunch, exhibition & poster viewing

13:00 - 14:30

Lunch, exhibition & poster viewing

Offered paper - Modelling of iron metabolism within the metabolic network of yeast

13:00 - 13:15

Offered paper - Modelling of iron metabolism within the metabolic network of yeast

Offered paper - Regulation of macropinocytosis in Dictyostelium

13:15 - 13:30

Offered paper - Regulation of macropinocytosis in Dictyostelium

From amoeba to bedside: Epilepsy research in the social amoeba Dictyostelium

14:30 - 15:00

From amoeba to bedside: Epilepsy research in the social amoeba Dictyostelium

Human animal infections and risk surveillance (HAIRS) and emerging infection risks to human health

14:30 - 15:00

Human animal infections and risk surveillance (HAIRS) and emerging infection risks to human health

Genomics of the distinctive gut community of honey bees

14:30 - 15:00

Genomics of the distinctive gut community of honey bees

Using baker's yeast for production of sustainable ingredients in health, wellness and nutrition

14:30 - 15:00

Using baker's yeast for production of sustainable ingredients in health, wellness and nutrition

Protein transport by the bacterial Tat pathway

14:30 - 15:00

Protein transport by the bacterial Tat pathway

Microbial genomics and beyond

14:30 - 15:00

Microbial genomics and beyond

Offered paper - The expression of the human cytomegalovirus US28 gene is necessary for the establishment of latency in early myeloid cells

14:30 - 14:42

Offered paper - The expression of the human cytomegalovirus US28 gene is necessary for the establishment of latency in early myeloid cells

Offered paper - Avian influenza: can antigenic drift lead to an augmented zoonotic potential?

14:30 - 14:42

Offered paper - Avian influenza: can antigenic drift lead to an augmented zoonotic potential?

Offered paper - Bluetongue virus expresses a small protein from a second open reading frame in segment 10

14:30 - 14:42

Offered paper - Bluetongue virus expresses a small protein from a second open reading frame in segment 10

Offered oral - Novel restriction factor RNA-associated early-stage anti-viral factor (REAF) inhibits human and simian immunodeficiency viruses

14:30 - 14:42

Offered oral - Novel restriction factor RNA-associated early-stage anti-viral factor (REAF) inhibits human and simian immunodeficiency viruses

Offered paper - In vivo association of HPV16 E2 with Rad50-interacting protein 1 (Rint1) and its role in viral genome replication

14:42 - 14:54

Offered paper - In vivo association of HPV16 E2 with Rad50-interacting protein 1 (Rint1) and its role in viral genome replication

Offered paper - Developing a PP7-based system to capture proteins involved in viral RNA recognition by RLRs

14:42 - 14:54

Offered paper - Developing a PP7-based system to capture proteins involved in viral RNA recognition by RLRs

Offered paper - Analysis of mutations in domain I of the hepatitis C virus non-structural NS5A protein

14:42 - 14:54

Offered paper - Analysis of mutations in domain I of the hepatitis C virus non-structural NS5A protein

Offered oral - Uncoating of HIV-1 capsid is triggered after the first stand transfer of reverse transcription

14:42 - 14:54

Offered oral - Uncoating of HIV-1 capsid is triggered after the first stand transfer of reverse transcription

Offered paper - The human cytomegalovirus IE1 protein rewires STAT3 to STAT1 signalling tempering viral replication

14:54 - 15:06

Offered paper - The human cytomegalovirus IE1 protein rewires STAT3 to STAT1 signalling tempering viral replication

Offered paper - The role of influenza A virus ribonucleoprotein structure in interferon induction

14:54 - 15:06

Offered paper - The role of influenza A virus ribonucleoprotein structure in interferon induction

Offered paper - Bluetongue virus infection of bovine monocytes is altered in the presence of Culicoides sonorensis salivary proteins

14:54 - 15:06

Offered paper - Bluetongue virus infection of bovine monocytes is altered in the presence of Culicoides sonorensis salivary proteins

Offered oral - A novel lentiviral vector model to investigate the mechanism of insertional mutagenesis by aberrant splicing

14:54 - 15:06

Offered oral - A novel lentiviral vector model to investigate the mechanism of insertional mutagenesis by aberrant splicing

Gene expression in a remnant chloroplast: The plasmodium apicoplast

15:00 - 15:30

Gene expression in a remnant chloroplast: The plasmodium apicoplast

The management of patients with herpes simplex encephalitis – is there a case for steroids?

15:00 - 15:30

The management of patients with herpes simplex encephalitis – is there a case for steroids?

The DrosophilaSpiroplasma interaction as a model to dissect the molecular mechanisms underlying insect endosymbiosis

15:00 - 15:30

The DrosophilaSpiroplasma interaction as a model to dissect the molecular mechanisms underlying insect endosymbiosis

Exploiting microbial diversity for the redesign of bacterial organelles

15:00 - 15:30

Exploiting microbial diversity for the redesign of bacterial organelles

Offered paper - Metal storage in bacterial and archaeal iron megastores: half ferritin, half virus

15:00 - 15:15

Offered paper - Metal storage in bacterial and archaeal iron megastores: half ferritin, half virus

Offered paper - Prevalence and molecular types of Clostridium difficile isolates from faecal specimens of patients in a tertiary care centre

15:00 - 15:15

Offered paper - Prevalence and molecular types of Clostridium difficile isolates from faecal specimens of patients in a tertiary care centre

Offered paper - Use of chemical biology to identify cellular protein kinases involved in histone phosphorylation during human cytomegalovirus replication

15:06 - 15:18

Offered paper - Use of chemical biology to identify cellular protein kinases involved in histone phosphorylation during human cytomegalovirus replication

Offered paper - Identification of sequence polymorphisms in segment 3 of H9N2 avian influenza viruses that affect PA-X activity

15:06 - 15:18

Offered paper - Identification of sequence polymorphisms in segment 3 of H9N2 avian influenza viruses that affect PA-X activity

Offered paper - Characterisation of over 50 novel, infectious, chimeric hepatitis C virus clones incorporating genotype 1, 2 and 3 patient-derived glycoproteins

15:06 - 15:18

Offered paper - Characterisation of over 50 novel, infectious, chimeric hepatitis C virus clones incorporating genotype 1, 2 and 3 patient-derived glycoproteins

Offered oral - A novel cis-acting element affecting HIV replication

15:06 - 15:18

Offered oral - A novel cis-acting element affecting HIV replication

Offered paper - Starvation survival of Bacillus subtilis without sporulation

15:15 - 15:30

Offered paper - Starvation survival of Bacillus subtilis without sporulation

Offered paper - Emergence of host-adapted Salmonella enteritidis through rapid evolution in an immunocompromised host

15:15 - 15:30

Offered paper - Emergence of host-adapted Salmonella enteritidis through rapid evolution in an immunocompromised host

Offered paper - Human cytomegalovirus latency-associated protein LUNA regulates latent viral gene expression by disrupting cellular PML bodies

15:18 - 15:30

Offered paper - Human cytomegalovirus latency-associated protein LUNA regulates latent viral gene expression by disrupting cellular PML bodies

Offered paper - The influenza A virus PB1-F2 protein enhances virus transmission in chickens

15:18 - 15:30

Offered paper - The influenza A virus PB1-F2 protein enhances virus transmission in chickens

Offered paper - Development of rationally attenuated live vaccines for effective control of infectious bronchitis

15:18 - 15:30

Offered paper - Development of rationally attenuated live vaccines for effective control of infectious bronchitis

Offered oral - A role for genomic RNA in regulating the maturation of the HIV-1 virion core

15:18 - 15:30

Offered oral - A role for genomic RNA in regulating the maturation of the HIV-1 virion core

Circadian clock research in the pico-eukaryote Ostreococcus tauri: A bacterial-sized cell with a yeast-sized genome

15:30 - 16:00

Circadian clock research in the pico-eukaryote Ostreococcus tauri: A bacterial-sized cell with a yeast-sized genome

Refreshments and exhibition

15:30 - 16:00

Refreshments and exhibition

Development of RNAi delivery tools using gut symbionts of blood-and sap-feeding insects

15:30 - 16:00

Development of RNAi delivery tools using gut symbionts of blood-and sap-feeding insects

Refreshments and exhibition

15:30 - 16:00

Refreshments and exhibition

Offered paper - Structure of the crystalline native Clostridium difficile S-layer

15:30 - 15:45

Offered paper - Structure of the crystalline native Clostridium difficile S-layer

Offered paper - Bacillus subtilis with a linear chromosome

15:30 - 15:45

Offered paper - Bacillus subtilis with a linear chromosome

Offered paper - Nuclear pore complex remodelling in Kaposi's sarcoma-associated herpesvirus lytic infection

15:30 - 15:42

Offered paper - Nuclear pore complex remodelling in Kaposi's sarcoma-associated herpesvirus lytic infection

Offered paper - Why are potassium channels required for the multiplication of bunyaviruses?

15:30 - 15:42

Offered paper - Why are potassium channels required for the multiplication of bunyaviruses?

Offered paper - Detection of undefined RNA secondary structure within the non-structural region of the FMDV genome

15:30 - 15:42

Offered paper - Detection of undefined RNA secondary structure within the non-structural region of the FMDV genome

Refreshments and exhibition

15:30 - 16:00

Refreshments and exhibition

Offered paper - CTCF regulates differentiation-dependent human papillomavirus (HPV) gene expression

15:42 - 15:54

Offered paper - CTCF regulates differentiation-dependent human papillomavirus (HPV) gene expression

Offered paper - The potential for novel combination therapies targeting the M2 ion channel of pandemic influenza viruses

15:42 - 15:54

Offered paper - The potential for novel combination therapies targeting the M2 ion channel of pandemic influenza viruses

Offered paper - The fourth non-structural protein of African horse sickness virus

15:42 - 15:54

Offered paper - The fourth non-structural protein of African horse sickness virus

Offered paper - What are the benefits of aging for bacteria and what is the evidence?

15:45 - 16:00

Offered paper - What are the benefits of aging for bacteria and what is the evidence?

Offered paper - How variable is variability: how different are the phase variable genes of Campylobacter strains?

15:45 - 16:00

Offered paper - How variable is variability: how different are the phase variable genes of Campylobacter strains?

Refreshments and exhibition

15:54 - 16:24

Refreshments and exhibition

Refreshments and exhibition

15:54 - 16:24

Refreshments and exhibition

Refreshments and exhibition

15:54 - 16:24

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Cats, rats and bats: Rabies clinical service case histories and management issues

16:00 - 16:30

Cats, rats and bats: Rabies clinical service case histories and management issues

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Offered paper - Promoting microbiology education through the iGEM synthetic biology competition

16:00 - 16:15

Offered paper - Promoting microbiology education through the iGEM synthetic biology competition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Refreshments and exhibition

16:00 - 16:30

Refreshments and exhibition

Offered oral - Characterisation of the expression of novel endogenous retroviruses and immune interactions in a macaque model

16:00 - 16:12

Offered oral - Characterisation of the expression of novel endogenous retroviruses and immune interactions in a macaque model

Offered oral - Dendritic cell bio-marker of protection following vaccination with live attenuated SIV

16:12 - 16:24

Offered oral - Dendritic cell bio-marker of protection following vaccination with live attenuated SIV

Offered paper - GlasGlow: Engineering glow in the dark biology

16:15 - 16:30

Offered paper - GlasGlow: Engineering glow in the dark biology

Offered paper - Spatial analysis of nascent protein synthesis and association with PML bodies during HSV infection revealed by click chemistry

16:24 - 16:36

Offered paper - Spatial analysis of nascent protein synthesis and association with PML bodies during HSV infection revealed by click chemistry

Offered paper - In vitro and in vivo growth alter the population dynamic and properties of a Jeryl Lynn mumps vaccine

16:24 - 16:36

Offered paper - In vitro and in vivo growth alter the population dynamic and properties of a Jeryl Lynn mumps vaccine

Offered paper - Isolation and analysis of recombinants from mixed virus infections using next generation sequencing (NGS) and bioinformatics

16:24 - 16:36

Offered paper - Isolation and analysis of recombinants from mixed virus infections using next generation sequencing (NGS) and bioinformatics

Offered oral - European research infrastructures for poverty related diseases (EURIPRED)

16:24 - 16:36

Offered oral - European research infrastructures for poverty related diseases (EURIPRED)

Divergence, adaptation and loss of genome maintenance pathways in trypanosomatids

16:30 - 17:00

Divergence, adaptation and loss of genome maintenance pathways in trypanosomatids

Molecular dissection of phytoplasma modulation of plant hosts and insect vectors

16:30 - 17:00

Molecular dissection of phytoplasma modulation of plant hosts and insect vectors

Offered paper - AlcoPatch: Synthetic biology tools as lifestyle accessories

16:30 - 16:45

Offered paper - AlcoPatch: Synthetic biology tools as lifestyle accessories

Offered paper - Plasmid-induced filamentation in Salmonella used in bacteria mediated cancer research

16:30 - 16:45

Offered paper - Plasmid-induced filamentation in Salmonella used in bacteria mediated cancer research

Offered paper - Gene mobility promotes the persistence of a bacterial social trait

16:30 - 16:45

Offered paper - Gene mobility promotes the persistence of a bacterial social trait

Offered paper - Low oxygen regulates hepatitis B virus transcription

16:36 - 16:48

Offered paper - Low oxygen regulates hepatitis B virus transcription

Offered paper - Subversion of autophagy by influenza A virus M2 protein

16:36 - 16:48

Offered paper - Subversion of autophagy by influenza A virus M2 protein

Offered paper - Characterisation of genes involved in the propagation failure of bluetongue virus serotype 26 (BTV-26) in Culicoides sonorensis cell line (KC) and adult Culicoides sonorensis midges

16:36 - 16:48

Offered paper - Characterisation of genes involved in the propagation failure of bluetongue virus serotype 26 (BTV-26) in Culicoides sonorensis cell line (KC) and adult Culicoides sonorensis midges

Engineering yeast to produce plant flavours

16:45 - 17:15

Engineering yeast to produce plant flavours

Offered paper - Functional analysis of an unusual type IV pilus in the Gram-positive Streptococcus sanguinis

16:45 - 17:00

Offered paper - Functional analysis of an unusual type IV pilus in the Gram-positive Streptococcus sanguinis

Offered paper - Source-sink plasmid transfer dynamics maintain gene mobility and facilitate interspecific gene transfer in soil bacterial communities

16:45 - 17:00

Offered paper - Source-sink plasmid transfer dynamics maintain gene mobility and facilitate interspecific gene transfer in soil bacterial communities

Offered paper - The relationship between Merkel cell polyomavirus small T (ST) antigen and cell adhesion molecules – implication for metastatis

16:48 - 17:00

Offered paper - The relationship between Merkel cell polyomavirus small T (ST) antigen and cell adhesion molecules – implication for metastatis

Offered paper - Morphogenesis of respiratory syncytial virus in human primary nasal ciliated epithelial cells

16:48 - 17:00

Offered paper - Morphogenesis of respiratory syncytial virus in human primary nasal ciliated epithelial cells

Offered paper - New insights into the honey bee pathogen, deformed wing virus

16:48 - 17:00

Offered paper - New insights into the honey bee pathogen, deformed wing virus

Genome surveillance in neurospora

17:00 - 17:30

Genome surveillance in neurospora

Regulation and biosynthesis of natural products produced by insect-associated Actinomycetes

17:00 - 17:30

Regulation and biosynthesis of natural products produced by insect-associated Actinomycetes

Offered paper - Promoting stable polyphosphate accumulation in E. coli using recombinant bacterial microcompartment-directed polyphosphate kinase

17:00 - 17:15

Offered paper - Promoting stable polyphosphate accumulation in E. coli using recombinant bacterial microcompartment-directed polyphosphate kinase

Offered paper - Enterococcus faecium genome dynamics during long-term patient gut colonisation

17:00 - 17:15

Offered paper - Enterococcus faecium genome dynamics during long-term patient gut colonisation

Offered paper - Next generation sequencing reveals novel cellular targets for Merkel cell polyomavirus miRNA

17:00 - 17:12

Offered paper - Next generation sequencing reveals novel cellular targets for Merkel cell polyomavirus miRNA

Offered paper - A Staphylococcus aureus secreted protein enhances influenza A virus replication in vitro

17:00 - 17:12

Offered paper - A Staphylococcus aureus secreted protein enhances influenza A virus replication in vitro

Offered paper - Cell cycle regulation through translational control of RGC-32 in EBV immortalised B cells

17:12 - 17:24

Offered paper - Cell cycle regulation through translational control of RGC-32 in EBV immortalised B cells

Offered paper - BPIFA1/SPLUNC1 restricts influenza A virus infection in the host by influencing the adaptive immune response

17:12 - 17:24

Offered paper - BPIFA1/SPLUNC1 restricts influenza A virus infection in the host by influencing the adaptive immune response

Offered paper - Defining the function of multiple copies of 3B in foot-and-mouth disease virus RNA replication

17:12 - 17:24

Offered paper - Defining the function of multiple copies of 3B in foot-and-mouth disease virus RNA replication

Microbial metabolic engineering to deliver better products for a better planet

17:15 - 17:45

Microbial metabolic engineering to deliver better products for a better planet

Offered paper - Investigating YecA, a potential component of the Sec machinery of Escherichia coli

17:15 - 17:30

Offered paper - Investigating YecA, a potential component of the Sec machinery of Escherichia coli

Offered paper - A longitudinal study of elderly patients identifies dynamic bacterial and host responses to long-term Escherichia coli colonisation of the bladder

17:15 - 17:30

Offered paper - A longitudinal study of elderly patients identifies dynamic bacterial and host responses to long-term Escherichia coli colonisation of the bladder

Offered paper - Characterisation of the antiviral activity of a chloride ion channel inhibitor on human cytomegalovirus

17:24 - 17:36

Offered paper - Characterisation of the antiviral activity of a chloride ion channel inhibitor on human cytomegalovirus

Offered paper - Identification of the genetic signatures in the haemagglutinin (HA) protein that control the stability of live attenuated influenza vaccines

17:24 - 17:36

Offered paper - Identification of the genetic signatures in the haemagglutinin (HA) protein that control the stability of live attenuated influenza vaccines

Offered paper - Serial infection of porcine rotavirus through cell lines deficient for innate antiviral mechanisms

17:24 - 17:36

Offered paper - Serial infection of porcine rotavirus through cell lines deficient for innate antiviral mechanisms

Offered paper - Genomic analyses of bee-associated Wolbachia reveal a recent biotin operon transfer and enable the timing of Wolbachia diversification

17:30 - 17:45

Offered paper - Genomic analyses of bee-associated Wolbachia reveal a recent biotin operon transfer and enable the timing of Wolbachia diversification

Offered paper - Localising autotransporter EspC during secretion to identify potential targets for novel antimicrobials

17:30 - 17:45

Offered paper - Localising autotransporter EspC during secretion to identify potential targets for novel antimicrobials

Offered paper - Sequencing a piece of history: Complete genome sequence of the first Escherichia coli isolate

17:30 - 17:45

Offered paper - Sequencing a piece of history: Complete genome sequence of the first Escherichia coli isolate

Offered paper - Novel non-immune suppresive analogues of cyclosporine A promote a post-DNA replication defect in human cytomegalovirus replication

17:36 - 17:48

Offered paper - Novel non-immune suppresive analogues of cyclosporine A promote a post-DNA replication defect in human cytomegalovirus replication

Offered paper - The contribution of specific haemagglutinin mutations to equine influenza vaccine breakdown

17:36 - 17:48

Offered paper - The contribution of specific haemagglutinin mutations to equine influenza vaccine breakdown

Offered paper - Translation of Tulane virus, a novel surrogate for human norovirus

17:36 - 17:48

Offered paper - Translation of Tulane virus, a novel surrogate for human norovirus

Offered paper - New insights into interactions between entomopathogenic fungi and insect hosts

17:45 - 18:00

Offered paper - New insights into interactions between entomopathogenic fungi and insect hosts

Offered paper - Dissection of the molecular determinants and pathways involved in Hepatitis B virus (HBV) entry into hepatocytes

17:48 - 18:00

Offered paper - Dissection of the molecular determinants and pathways involved in Hepatitis B virus (HBV) entry into hepatocytes

Offered paper - 'Trans'-lating the untranslated region: Complementation studies of the FMDV 5' UTR

17:48 - 18:00

Offered paper - 'Trans'-lating the untranslated region: Complementation studies of the FMDV 5' UTR

Colworth Prize Lecture: Exploiting new biological targets from a whole-cell phenotypic screening campaign for TB drug discovery

18:10 - 19:00

Colworth Prize Lecture: Exploiting new biological targets from a whole-cell phenotypic screening campaign for TB drug discovery

Poster viewing, drinks & exhibition

19:00 - 21:00

Poster viewing, drinks & exhibition

iGEM poster exhibition

19:15 - 20:15

iGEM poster exhibition

Meet the Speakers

19:30 - 20:30

Meet the Speakers

Science Showoff

20:15 - 22:00

Science Showoff

Thursday 24 March, Morning

Exhibition, morning coffee, tea and pastries, and Close

07:00 - 09:20

Exhibition, morning coffee, tea and pastries, and Close

Nucleic acid delivery systems for RNA therapy and gene editing

09:30 - 10:00

Nucleic acid delivery systems for RNA therapy and gene editing

HIV restriction – striking early

09:30 - 10:00

HIV restriction – striking early

Global reprogramming of the Yersinia pseudotuberculosis transcriptional landscape in response to temperature and host signals

09:40 - 10:10

Global reprogramming of the Yersinia pseudotuberculosis transcriptional landscape in response to temperature and host signals

The role bacterial endosymbionts play in male killing by ladybirds

09:45 - 10:15

The role bacterial endosymbionts play in male killing by ladybirds

Reading, writing and editing a genome: An emerging frontier in synthetic biology

10:00 - 10:30

Reading, writing and editing a genome: An emerging frontier in synthetic biology

Offered paper - E6 mediated serine phosphorylation of STAT3 is critical for the human papillomavirus lifecycle

10:00 - 10:15

Offered paper - E6 mediated serine phosphorylation of STAT3 is critical for the human papillomavirus lifecycle

A structural basis for the silencing of foreign DNA by bacteria

10:10 - 10:40

A structural basis for the silencing of foreign DNA by bacteria

Offered paper - Investigating effects of co-infection on endosymbiont function in aphids

10:15 - 10:30

Offered paper - Investigating effects of co-infection on endosymbiont function in aphids

The role played by autophagy during viral infection

10:15 - 10:45

The role played by autophagy during viral infection

Refreshments and exhibition

10:30 - 11:00

Refreshments and exhibition

Refreshments and exhibition

10:30 - 11:00

Refreshments and exhibition

Refreshments and exhibition

10:40 - 11:10

Refreshments and exhibition

Refreshments and exhibition

10:45 - 11:15

Refreshments and exhibition

Using inherited bacteria as a way to stop mosquitoes from transmitting dengue: The Eliminate Dengue program

11:00 - 11:30

Using inherited bacteria as a way to stop mosquitoes from transmitting dengue: The Eliminate Dengue program

Application of genome editing technology in livestock

11:00 - 11:30

Application of genome editing technology in livestock

Offered paper - The global regulatory role of the RNA-binding protein CsrA in Escherichia coli

11:10 - 11:25

Offered paper - The global regulatory role of the RNA-binding protein CsrA in Escherichia coli

Viruses transfer the antiviral second messenger cgamp between cells

11:15 - 11:45

Viruses transfer the antiviral second messenger cgamp between cells

Random switching and global expression changes in the pneumococcus

11:25 - 11:55

Random switching and global expression changes in the pneumococcus

Who’s in there: Gut microbes, sexual behaviour and host fitness in fruitflies

11:30 - 12:00

Who’s in there: Gut microbes, sexual behaviour and host fitness in fruitflies

The use of phage integrases for genome engineering and metabolic pathway assembly

11:30 - 12:00

The use of phage integrases for genome engineering and metabolic pathway assembly

Lunch, exhibition & poster viewing

12:00 - 13:00

Lunch, exhibition & poster viewing

Thursday 24 March, Afternoon

The greater picture: Evolutionary implications of antimicrobial defenses in beewolves

13:00 - 13:30

The greater picture: Evolutionary implications of antimicrobial defenses in beewolves

ClosTron for genome editing in Clostridium

13:00 - 13:30

ClosTron for genome editing in Clostridium

Genetic disorders in bacteria

13:00 - 13:30

Genetic disorders in bacteria

HIV-1 restriction by SAMHD1

13:00 - 13:30

HIV-1 restriction by SAMHD1

Fat flies: How the gut microbiota shapes host energy metabolism

13:30 - 14:00

Fat flies: How the gut microbiota shapes host energy metabolism

Structural insight into Cre/loxP recombinase for the engineering of a new specific anti-HIV recombinase

13:30 - 14:00

Structural insight into Cre/loxP recombinase for the engineering of a new specific anti-HIV recombinase

Offered paper - Arginine is a critical substrate for the pathogenesis of P. aeruginosa in burn wound infections

13:30 - 13:45

Offered paper - Arginine is a critical substrate for the pathogenesis of P. aeruginosa in burn wound infections

Offered paper - The role of long-range chromatin reorganisation by Epstein-Barr virus in lymphoma development

13:30 - 13:45

Offered paper - The role of long-range chromatin reorganisation by Epstein-Barr virus in lymphoma development

Offered paper - Climbing Mount Improbable: Laboratory-based evolution of acid resistance in E. coli leads to a common transcriptional and phenotypic landscape via two distinct genomic routes

13:45 - 14:00

Offered paper - Climbing Mount Improbable: Laboratory-based evolution of acid resistance in E. coli leads to a common transcriptional and phenotypic landscape via two distinct genomic routes

Offered paper - Investigating the role of NS5A domain 3 in protecting hepatitis C virus proteins from degradation

13:45 - 14:00

Offered paper - Investigating the role of NS5A domain 3 in protecting hepatitis C virus proteins from degradation

Microbiome assembly in leaf-cutter ants

14:00 - 14:30

Microbiome assembly in leaf-cutter ants

Offered paper - Making mycobacterial steroids for industry

14:00 - 14:15

Offered paper - Making mycobacterial steroids for industry

Refreshments and exhibition

14:00 - 14:30

Refreshments and exhibition

The proteome under viral attack

14:00 - 14:30

The proteome under viral attack

Offered paper - Large serine integrases for synthetic biology

14:15 - 14:30

Offered paper - Large serine integrases for synthetic biology

Refreshments and exhibition

14:30 - 15:00

Refreshments and exhibition

Refreshments and exhibition

14:30 - 15:00

Refreshments and exhibition

Transfer of noncoding DNA drives regulatory rewiring in bacteria

14:30 - 15:00

Transfer of noncoding DNA drives regulatory rewiring in bacteria

Wolbachia-mediated protection of insect hosts against pathogens

15:00 - 15:30

Wolbachia-mediated protection of insect hosts against pathogens

Xer-cise & X-mark: Plasmid and chromosome engineering using Xer recombinases

15:00 - 15:30

Xer-cise & X-mark: Plasmid and chromosome engineering using Xer recombinases

Using experimental evolution, genome resequencing and transcriptomics to understand mechanisms of co-evolution between P. aeruginosa and plasmids

15:00 - 15:30

Using experimental evolution, genome resequencing and transcriptomics to understand mechanisms of co-evolution between P. aeruginosa and plasmids

Offered paper - Drosophila melanogaster gut microbiota: emergent and dependent properties

15:30 - 15:45

Offered paper - Drosophila melanogaster gut microbiota: emergent and dependent properties

Radical recoding of microbial genomes

15:30 - 16:00

Radical recoding of microbial genomes

Unravelling regulation networks using mathematical modelling

15:30 - 16:00

Unravelling regulation networks using mathematical modelling

Offered oral - Getting around: the evolutionary ecology of host shifts by heritable microbes

15:45 - 16:00

Offered oral - Getting around: the evolutionary ecology of host shifts by heritable microbes
  • Abstracts

    Abstract submission is now closed.

    All submitted oral abstracts are available in the online Programme.

    Posters

    All posters can be displayed throughout the Conference.

    The poster abstracts book can be downloaded below:

    Poster abstract book (PDF)

    Viewing times

    Monday 21 March
    19:00–21:00

    • Membrane transporters
    • Nutritional immunity: Metals at the host–pathogen interface

    Tuesday 22 March
    19:00–21:00

    • Microbial evasion of host defences
    • Post-translational modifications of proteins
    • Mining microbial diversity for pleasure and profit
    • Mycobacteria
    • The 'Red Queen' and the genome: conflict in shaping microbial evolution

    Wednesday 22 March
    19:00–21:00

    • Virus workshop: Positive strand RNA viruses
    • Virus workshop: DNA viruses
    • Virus workshop: CVN
    • The model microbe – how far can it go?
    • Environmental and applied microbiology forum
    • Virus workshop: Restriction factors
    • Prokaryotic infection forum
    • Virus workshop: Positive strand RNA viruses, ds RNA viruses including plant viruses
    • Prokaryotic cell biology forum
    • Prokaryotic genetics forum
    • Insights from within: Current advances in understanding microbial interactions with insects
    • Virus workshop: Retroviruses
    • Global transcriptional landscape: Small changes, big effects
    • Novel tools for manipulation of genes and genomes
    • Virus workshop: Viral haemorrhagic fevers

    In order to ensure your poster presentation is displayed correctly, you are asked to comply with the following:

    • Size of display: standard A0 size 841mm(w) x 1189mm(h) - your poster should not exceed these measurements.
    • Posters must be portrait orientation.
    • Posters will be displayed on poster boards measuring 1m(w) x 2m(h), one to a side.
    • Posters can ONLY be fixed by velcro (provided at conference).
    • Your viewing time and details on setting up and taking down will be advised prior to the conference.
    • Details on your poster number and location will be available onsite.
    • You are required to be available by your poster, during the designated time, to discuss the work presented.
    • Kindly note that the Society cannot forward any posters not collected after the conference.
    • Please ensure you remove your poster by the designated time. Posters that are not removed by this time may be disposed of by the venue.

    We have created a guide on how to give a poster presentation, which can be downloaded below:

    How to... give a poster presentation (PDF)

    Oral presentations

    In order to ensure your presentation runs smoothly, you are asked to comply with the following:

    • PowerPoint presentations - PC version - are brought to the conference on a USB memory stick.
    • PowerPoint presentations - Mac version - can only be accepted if you bring your own laptop and connecting cables.
    • Your presentation is given to the venue a/v support staff in the Speaker Preview Room at least 2 hours in advance of your presentation to ensure compatibility with the equipment available.

    We have created a guide on how to give an oral presentation, which can be downloaded below:

    How to... give an oral presentation (PDF)

    A companion video on top tips for presentation is also available:

  • Registration

    Online registration for the Annual Conference is now closed. Registrations will now only be accepted onsite.

    What's included in your registration fee?
    • Admission to all scientific sessions
    • Admission to lunch time and evening engagement and networking events
    • Full access to the trade exhibition
    • Entrance to the social programme
    • Lunch Monday to Thursday
    • Tea and coffee breaks Monday to Thursday
    • Vouchers for two free drinks during the poster viewing sessions on Monday, Tuesday and Wednesday evening
    • A delegate bag and conference material
    • A conference programme book
    • Access to an online abstracts book
    • Certificate of participation
    • CPD Points
    Conference Grants

    Applications for funding to attend the Annual Conference 2016 have now closed. Applicants will be notified of the outcome by 10 February 2016.

    The Society offers funds via the Conference Grant schemes to support the attendance of members at all stages of their careers:

    See the relevant pages for further details including application forms and full terms and conditions.

    Eligible Full members requiring funding can apply via the Travel Grant scheme. Members may apply to the 1 March 2016 closing date for the Annual Conference alone.

    For all Conference Grants enquiries, please contact grants@microbiologysociety.org

    Registration rates

    Registration Categories

    (all rates are per day)

    Early Bird
    Registration Fees

    Available until

    23:59, Monday 22 February 2016

    Full Price
    Registration Fees

    Available until

    23:59, Monday 14 March 2016

    Late
    Registration Fees

    Onsite only, available from

    Sunday 20 March 2016

     

    Per day
    Per day
    Per day

    Affiliate

    £140

    £150

    £160

    Full Concessionary Member

    £50

    £60

    £70

    Full Member

    £70

    £80

    £90

    Honorary Member

    £0

    £0

    £0

    International Associate Member resident in all other countries (excluding UK and Ireland)

    £140

    £150

    £160

    International Associate Member resident in lower-middle income economies***

    £50

    £60

    £70

    International Associate Member resident in low income economies***

    £0

    £0

    £0

    Postgraduate Student Member

    £50

    £60

    £70

    Undergraduate Student Member

    £0

    £0

    £0

    Non-Member

    £150

    £160

    £170

    CVN Member (Attendance Tuesday PM and All Day Wednesday)

    £120

    £130

    £140

    CBMNet Member (Attendance All Day Monday and Tuesday AM)

    £120

    £130

    £140

    *** See: List of Lower-Middle-Income and Low-Income Economies

    Onsite Registration

    The Registration Desk will be located in the foyer at the ACC Liverpool and open as follows:

    • Sunday 20 March: 16:00 – 20:30
    • Monday 21 March: 07:00 – 21.00
    • Tuesday 22 March: 07:00 – 21.00
    • Wednesday 23 March: 07:00 – 21.00
    • Thursday 24 March: 07:30 – 15:00
    Registration confirmation

    Upon registration you should receive an automated confirmation email. Please contact conferences@microbiologysociety.org if after 24 hours this has not been received.

    Visa applications

    If you need a letter of invitation for a visa application, we will be happy to supply this after we have received full payment. To find out if you need a visa to visit the UK, please visit the UK visa and immigration website.

    It is the policy of the Microbiology Society not to supply an invitation letter to any delegate without payment and we will not reply to any request from an unregistered delegate. When the delegate has paid, the Conference Office will email back a confirmation/receipt letter and, upon request, a letter of invitation, which may be used to obtain the necessary visa.

    Please note that all conference delegates are responsible for their own travel and visa arrangements; the Microbiology Society will not take any responsibility for travel or visa problems.

    Payment information

    All registration fees must be paid in full BEFORE arrival at the conference. Any outstanding registration fees must be paid before admittance will be granted to the conference.

    Cancellations

    Refunds are not provided, however substitutions of attendees can be made at any time by contacting conferences@microbiologysociety.org.

  • Speakers

    Invited speakers

    Every year we invite international speakers to represent all areas of microbiology. Each person below is highly recognised in their field.

    • Josephine Abi-Ghanem (University of Bordeaux, France)
    • Roberto Amato (Wellcome Trust, Sanger Institute, UK)
    • Daniel Anderson (Massachusetts Institute of Technology, USA)
    • Ingo Autenrieth (University of Tübingen, Germany)
    • Jürg Bähler (University College London, UK)
    • Mona Bajaj-Elliot (University College London, UK)
    • Christopher Basler (Icahn School of Medicine at Mount Sinai, USA)
    • Matthew Baylis (Institute of Infection and Global Health, University of Liverpool, UK)
    • Dörte Becher (University of Greifswald, Germany)
    • Jules Beekwilder (Wageningen University, Netherlands)
    • Kirsten Benjamin (Amyris Incorporated, USA)
    • Anne Bertolotti (University of Cambridge, UK)
    • Robert Beynon (University of Liverpool, UK)
    • Paul Bienasz (The Rockefeller University, USA)
    • Roslyn Bill (Aston University, UK)
    • Kate Bishop (The Francis Crick Institute, UK)
    • Damer Blake (Royal Veterinary College, UK)
    • Koos Boomsma (University of Copenhagen, Denmark)
    • Catharine Bosio (Rocky Mountain Laboratories, USA)
    • Andrew Bowie (Trinity College Dublin, Ireland)
    • Paola Branduardi (University of Milan, Italy)
    • Nichole Broderick (University of Connecticut, USA)
    • Priscille Brodin (Inserm, France)
    • Igor Brodsky (University of Pennsylvania, USA)
    • Daniel Brooks (University of Nebraska, USA)
    • Roland Brosch (Institut Pasteur, France)
    • Nigel Brown (University of Edinburgh, UK)
    • Arturo Casadeval (John Hopkins, USA)
    • Jennifer Cavet (University of Manchester, UK)
    • Tracey Chapman (University of East Anglia, UK)
    • Sara Cherry (University of Pennsylvania, USA)
    • James Chong (University of York, UK)
    • Tim Claussen (Research Institute of Molecular Pathology, Austria)
    • Stewart Cole (EPFL, Switzerland)
    • Pascale Cossart (Institut Pasteur, France)
    • Sarah Coulthurst (University of Dundee, UK)
    • Rocky Cranenburgh (Prokarium, UK)
    • Ileana Cristea (Princeton University, USA)
    • Sue Crosthwaite (University of Manchester, UK)
    • Allister Crow (University of Cambridge, UK)
    • Jean-Marc Daran (Delft University of Technology, Netherlands)
    • Anne Dell (Imperial College London, UK)
    • Emma Denham (University of Warwick, UK)
    • Petra Dersch (Helmholtz Centre for Infection Research, Germany)
    • Angela Douglas (Cornell University, USA)
    • David Drew (University of Stockholm, Sweden)
    • Michael Eisenbach (Weizmann Institute of Science, Israel)
    • Tom Ellis (Imperial College London, UK)
    • Tobias Engl (Johannes Gutenberg University, Germany)
    • Rachel Exley (University of Oxford, UK)
    • Mike Ferguson (University of Dundee, UK)
    • Andres Floto (University of Cambridge, UK)
    • Gad Frankel (Imperial College London, UK)
    • Catarina Gadelha (University of Nottingham, UK)
    • Lucy Gilbert (The James Hutton Institute, UK)
    • Louise Glass (University of California, Berkeley, USA)
    • Matthew Goddard (University of Lincoln, UK)
    • Stephen Gordon (University College Dublin, Ireland)
    • Caroline Goujon (University of Montpellier, France)
    • Neil Gow (University of Aberdeen, UK)
    • Dave Grainger (University of Birmingham, UK)
    • Jørgen Hansen (Evolva, Denmark)
    • Iain Haysom (Bath Spa University, UK)
    • Peter Henderson (University of Leeds, UK)
    • Heiko Herwald (Lund University, Sweden)
    • Roger Hewson (Public Health England, UK)
    • Hubert Hilbi (University of Zurich, Switzerland)
    • Saskia Hogenhout (John Innes Centre, UK)
    • Matthias Horn (University of Vienna, Austria)
    • Paul Hoskisson (University of Strathclyde, UK)
    • Alan Huett (University of Nottingham, UK)
    • Matthew Hutchings (University of East Anglia, UK)
    • Sara Jabbari (University of Birmingham, UK)
    • Dirk jan Slotboom (University of Groningen, Netherlands)
    • Francis Jiggins (University of Cambridge, UK)
    • Kayla King (University of  Oxford, UK)
    • Jonas Klingström (Karolinska Institute, Sweden)
    • Eugene Koonin (NIH, USA)
    • Lars Leichert (Ruhr University Bochum, Germany)
    • Bruno Lemaitre (Global Health Institute, Switzerland)
    • Debbie Lindell (Technion University, Israel)
    • Kaspar Locher (ETH Zurich, Switzerland)
    • Craig MacLean (University of Oxford, UK)
    • Tamsin Majerus (University of Nottingham, UK)
    • Mike Malim (King's College London, UK)
    • Luisa Martinez-Pomares (University of Nottingham, UK)
    • Anthony Maurelli (University of Florida, USA)
    • Richard McCulloch (University of Glasgow, UK)
    • Anthony McDonnell (AMR Review, UK)
    • Helen McShane (University of Oxford, UK)
    • Mike Merrick (John Innes Centre, UK)
    • Jason Micklefield (University of Manchester, UK)
    • Mary Miller (Baton Rouge Community College, USA)
    • Nigel Minton (University of Nottingham, UK)
    • Nancy Moran (University of Texas, USA)
    • John Morrissey (University College Cork, Ireland)
    • Elke Mühlberger (Boston University, USA)
    • William Navarre (University of Toronto, Canada)
    • Sergey Nejentsev (University of Cambridge, UK)
    • Elke Nevoigt (Jacobs University, Germany)
    • Simon Newstead (University of Oxford, UK)
    • Ellen Nisbet (University of Cambridge, UK)
    • Julie Norville (Harvard Medical School, USA)
    • Marco Oggioni (University of Leicester, UK)
    • Scott O'Neill (Monash University, Australia)
    • Nina Papavasiliou (The Rockefeller University, USA)
    • Ian Paulsen (Macquarie University, Australia)
    • Bronwen Percival (Neal's Yard Dairy, UK)
    • Andreas Pichlmair (Max-Planck Institute of Biochemistry, Germany)
    • Stefan Pöhlmann (German Primate Center, Germany)
    • Bert Poolman (University of Groningen, Netherlands)
    • Stephen Porter (University of Exeter, UK)
    • Tal Pupko (Tel-Aviv University, Israel)
    • Beth Purse (Centre for Ecology and Hydrology, UK)
    • Amparo Querol (Institute of Agrochemistry and Food Technology, Spain)
    • Manuela Raffatellu (University of California, Irvine, USA)
    • Lalita Ramakrishnan (University of Cambridge, UK)
    • Jan Rehwinkle (University of Oxford, UK)
    • Adam Roberts (University College London, UK)
    • Ian Roberts (Institute of Food Research, UK)
    • Colin Robinson (University of Kent, UK)
    • Eric Rubin (Harvard T.H. Chan School of Public Health, USA)
    • Maria Salvato (University of Maryland School of Medicine, USA)
    • Karin Sauer (Binghamton University, USA)
    • Gavin Screaton (Imperial College London, UK)
    • Nigel Scrutton (University of Manchester, UK)
    • Ryan Seipke (University of Leeds, UK)
    • Oonagh Shannon (Lund University, Sweden)
    • Carmel Shortiss (University College Cork, Ireland)
    • Gerd Siebold (Ulm University, Germany)
    • Maggie Smith (University of York, UK)
    • Thierry Soldati (University of Geneva, Switzerland)
    • Catherine Stanton (Teagasc, Ireland)
    • Karen Stevenson (Moredun Research Institute, UK)
    • Ipek Tasan (University of Illinois, USA)
    • Gavin Thomas (University of York, UK)
    • Chris Thompson (University of Manchester, UK)
    • Ana Maria Tomás (Institute of Molecular and Cell Biology, Portugal)
    • Renee M. Tsolis (University of California, USA)
    • Miguel Valvano (Queen's University Belfast, UK)
    • Gerben van Ooijen (University of Edinburgh, UK)
    • Ronald Van Rij (Radboud University Medical Center, Netherlands)
    • Jos van Strijp (University Medical Center Utrecht, Netherlands)
    • Kevin Waldron (Newcastle University, UK)
    • Martin Warren (University of Kent, UK)
    • Friedemann Weber (Institute of Virology, Germany)
    • Eilike Weber-Ban (ETH Zurich, Switzerland)
    • George Weinstock (The Jackson University, UK)
    • Bruce Whitelaw (The Roslin Institute, UK)
    • Miranda Whitten (Swansea University, UK)
    • Tom Wileman (University of East Anglia, UK)
    • Robin Williams (Royal Holloway, UK)
    • Duncan Wilson (University of Aberdeen, UK)
    • Alan Wolfe (Loyola University, USA)
    • Ronald Wong (Institute of Molecular Biology, Germany)
    • Pei Yong-Shi (University of Texas, USA)
  • Venue and Accommodation

    Accommodation

    All accommodation can be booked online through Reservation Highway, who have secured a range of options to suit all budgets throughout Liverpool at discounted rates.

    Annual Conference 2016 Hotel List

    Annual Conference 2016 Reservation Highway Accommodation Booking Form

    Accommodation in a guesthouse is also available. For further information and booking, please contact Reservation Highway.

    Phone: +44 (0)1423 525577
    Email: admin@reservation-highway.co.uk

    Venue

    The conference will be held at the ACC Liverpool:

    Arena and Convention Centre Liverpool
    Kings Dock
    Liverpool Waterfront
    L3 4FP

    General enquiries: +44(0)151 475 8888
    Email: info@accliverpool.com

    Venue map

    Venue map

    Directions

    Please see the detailed map and directions on the ACC Liverpool website.

    By car

    If you are travelling using a sat nav, please use postcode L3 4FP. If your device doesn't recognise ACC Liverpool, you can try the following:

    • Use the postcode L3 4BX with the following coordinates LAT:53.396007 LONG:-2.99118).
    • Enter the city as 'Liverpool' and the road name as 'Queen's Wharf'.

    From the Wirral, Wales and the M53, leave the M53 motorway at junction 3 (Birkenhead) and follow the A552 for the Birkenhead (Queensway) Tunnel and Liverpool City Centre.

    From the south, leave the M6 at junction 21A and take the M62 to Liverpool. At the end of the M62, follow signs for Liverpool City Centre along Edge Lane, and then follow signs for the Waterfront.

    From the north, leave the M6 at junction 26 and follow signs for M58 Liverpool. Follow to the end of the M58 and then take signs for A59 Liverpool. Continue to follow signs for Liverpool City Centre until picking up signs for the Waterfront.

    The Liverpool Waterfront Car Park is signposted as 'Waterfront' on the city-wide 'available spaces' signage.

    By air

    Liverpool John Lennon Airport is the nearest international airport to the ACC Liverpool. The express bus service Route 500 runs between the airport and Liverpool City Centre, taking approximately 25 minutes and stopping within a five-minute walk of Liverpool ACC. For a timetable and route map please visit the Arriva Bus website. Please see the Liverpool Airport website for further details.

    National Express coaches run from Manchester Airport to Liverpool Coach Station and takes 50 minutes. Please see the National Express website for information about coach times and fares. Please see the Manchester Airport website for further information and a journey planner.

    By rail

    ACC Liverpool is a 20-minute walk from Liverpool Lime Street. You can also transfer at Lime Street onto the underground Wirral Line trains to James Street station (10-minute walk) or catch the CityLink bus (every 12 minutes) directly to ACC Liverpool. If travelling from outside Merseyside, you can catch an underground train to James Street station from Lime Street station, inclusive of the cost of your ticket.

    Information about train times and fares are available from the National Rail enquries website.

    Virgin Trains

    Virgin Trains offer discounted group travel for groups of between three and nine passengers travelling together. This currently stand at a 20% discount off Advance tickets booked through their website – for more information, visit the group tickets page of their website.

    By bus

    Most Liverpool city centre-bound buses will call at either Queen Square bus station (a 15-minute walk) or Liverpool ONE Bus Station, which is only a five-minute walk to ACC Liverpool.

    The CityLink bus links Queen Square Bus Station, James Street rail station, Lime Street station and Liverpool ONE Bus Station to ACC Liverpool. The CityLink bus service operates every 12 minutes as a circular service around the city centre.

    For up-to-date information on all bus, train and ferry services, call Traveline Merseyside on 0151 236 7676, open 8am to 8pm every day of the week, or visit the Merseytravel website.

    Coach

    For information about travel by coach please visit the National Express website.

    Car parking

    Please see the ACC Liverpool website for details on local car parks.

  • General information

    If this is your first conference, we have created a guide to help you get the most out of your attendance. This can be downloaded below:

    How to... get the most out of your first conference (PDF)

    Registration

    Registration opens at 07:00 each day and will be located by the main entrance at the ACC Liverpool. If you have any questions or need support, please visit the Conferences team here.

    Badges

    Badges are issued by the Microbiology Society and are only to be used by the named person for the days indicated. For security purposes, badges must be worn at all times during the Conference.

    Certificates of attendance

    A certificate of attendance can be requested at the Registration Desk or requested by email from conferences@microbiologysociety.org

    Continuing Professional Development (CPD)

    The Conference has been accredited by the Royal Society of Biology (114 credits), the Royal College of Pathologists (30 credits) and the Institute of Biomedical Science (38 credits). Ask at the Professional Development information desk for further information, or contact profdev@microbiologysociety.org. Those wishing to claim CPD credits should sign a daily register held at the Professional Development information desk, which is located next to registration.

    Mobile phones

    Please ensure your mobile phone is switched to silent mode or off during the scientific sessions.

    Programme changes

    While every effort has been made to ensure the programme is accurate, changes are unavoidable and we will ensure updates are provided throughout the Conference online.

    Posters

    Posters will be presented in Hall 2 and presenters will be by their posters on the day of their related session. An abstracts book can be located on our website and links to abstracts for oral presentations are now in our online programme.

    Passport to Prizes

    For a chance to win with our Passport to Prizes competition, you need to complete the quiz sheet in your delegate's bag. The prize draw will take place on Wednesday evening at the Microbiology Society stand and your entries must be in by lunchtime on Wednesday to be counted.

    Photography and filming at the Conference

    The Society will be carrying out filming and photography throughout the Conference. The images and videos will be used to promote the Conference and the activities of the Society. They may be used online, in Society publications, or for other PR and marketing purposes.

    If you do not wish to appear in photographs or films, please make this known to a member of the team.

    Recording

    Only recording set up with prior permission is authorised.

    Dietary requirements

    All disclosed dietary requirements made at the point of registration have been shared with the catering team at the ACC in advance. However, please ensure you ask for advice if required and the team will do their best to accommodate your needs.

    Twitter

    Delegates, exhibitors and speakers tweeting from the Conference are invited to include the hashtag #Microbio16 in their tweets. A Twitter feed will be displayed in the exhibition area. You can follow the Society on Twitter @MicrobioSoc.

    Wi-Fi

    The Wi-Fi has kindly been sponsored by Elsevier. To log on, go to your internet settings and select the network option Free_Wi-Fi. This will take you to the ACC Liverpool landing page, where you can click the 'free access' button.

  • Exhibition
    Confirmed exhibitors
    Exhibitor New England BioLabs

    Exhibitor Garland Science
    Exhibitor Taylor & Francis

    Exhibitor Nature Publishing Group
    Exhibitor Vitech Science Ltd Exhibitor Sheffield Hallam University Exhibitor Cambio Ltd
    Exhibitor Merck Millipore Exhibitor Applikon Biotechnology Exhibitor eLife
    Exhibitor Constant Systems Exhibitor University of Dundee Jalview Exhibitor MP Biomedicals
    Exhibitor Microbes NG Exhibitor Clontech Exhibitor PHE
    Exhibitor Biolegio Exhibitor Bioline Exhibitor Li-Cor
    Exhibitor Marketing Edinburgh Exhibitor Stratech Exhibitor Eppendorf

     

    Exhibitor floor plan

    Download floor plan

    Download exhibitor list

    Exhibitor and Promotion Guide

    The exhibition and sponsorship opportunities at the Annual Conference have now ended. To enquire about exhibition bookings for next year's event, please contact conferences@microbiologysociety.org

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